Zobrazeno 1 - 10
of 526
pro vyhledávání: '"M, Vergnes"'
Autor:
Louis L. Radulovic, Mark G. Vartanian, Jack J. Kinsora, Edward H. Bertram, Charles Taylor, Kevin A. Serpa, M. Vergnes
Publikováno v:
Epilepsy Research. 68:189-205
Pregabalin (Lyrica) is a novel amino acid compound that binds with high affinity to the alpha2-delta (alpha2-delta) auxiliary protein of voltage-gated calcium channels. In vivo, it potently prevents seizures, pain-related behaviors and has anxiolytic
Generalized non convulsive epilepsy (GNCE), also called absence or petit mal epilepsy, is a disease appearing during childhood. EEG, clinical, pharmacological and genetic characteristics differ from those of convulsive or focal epilepsies. No underly
Autor:
Frances M. Leslie, Olivier Civelli, Steven H.S. Lin, Craig W. Berridge, Amy C. Arai, John R. Huguenard, M. Vergnes, Rodrigo A. España
Publikováno v:
Neuroscience. 114:229-238
Prolactin releasing peptide (PrRP) is a recently identified neuropeptide that stimulates prolactin release from pituitary cells. The presence of its receptor outside the hypothalamic-pituitary axis suggests that it may have other functions. We presen
Publikováno v:
Neuroscience
Neuroscience, Elsevier-International Brain Research Organization, 2001, 105 (1), pp.181-201
Neuroscience, Elsevier-International Brain Research Organization, 2001, 105 (1), pp.181-201
International audience; In humans with absence epilepsy, spike-and-wave discharges develop in the thalamocortical system during quiet immobile wakefulness or drowsiness. The present study examined the initial stage of the spontaneous development of s
Autor:
Thierry Grisar, Christian Marescaux, Arlette Minet, Bernard Lakaye, M. Vergnes, B. de Borman, Lut Arckens
Publikováno v:
Experimental Neurology. 162:112-120
Differential mRNA display was carried out to find genes that are differentially regulated in the brain of a rat strain with absence epilepsy, the genetic absence epilepsy rats from Strasbourg (GAERS). Among the 32 differentially displayed cDNA fragme
Publikováno v:
Experimental Neurology. 161:714-723
Thalamocortical spike-and-wave discharges characterize the nonconvulsive absence seizures that occur spontaneously in genetic absence epilepsy rats from Strasbourg (GAERS), a selected strain of Wistar rats. GABA is crucial in the generation of absenc
Publikováno v:
Brain Research. 841:62-69
Patients with absence epilepsy frequently develop convulsions later in life. We were therefore interested whether tissue from rats with a genetic absence epilepsy is more prone to seizure generation than normal animals. We compared the epileptiform a
Publikováno v:
Neuroscience. 93:1173-1177
The susceptibility to develop cortically induced focal and generalized seizures was examined in Genetic Absence Epilepsy Rats from Strasbourg (GAERS), an inbred strain of Wistar rats with absence epilepsy. A GABA-withdrawal syndrome induced after sup
Publikováno v:
Experimental Neurology. 157:106-119
In a strain of Wistar rats selected in our laboratory, audiogenic seizures (AS), characterized by a wild running phase followed by a tonic seizure, can be elicited by exposure to sound. In these animals repeated daily stimulations induce permanent ch
Autor:
Willy Zorzi, Thierry Grisar, M. Vergnes, Christian Marescaux, B. de Borman, Arlette Minet, Bernard Lakaye
Publikováno v:
NeuroReport. 10:569-574
Low voltage-activated calcium channels are thought to play a key role in the generation of spike and waves discharges characteristic of absence epilepsy. Therefore, the expression level of mRNA encoding calcium channel alpha1E and alpha1G subunits wa