Zobrazeno 1 - 10
of 1 246
pro vyhledávání: '"M, Valverde"'
Autor:
M. Pilar Valdecantos, Laura Ruiz, Cintia Folgueira, Patricia Rada, Beatriz Gomez-Santos, Maite Solas, Ana B. Hitos, Joss Field, Vera Francisco, Carmen Escalona-Garrido, Sebastián Zagmutt, María Calderon-Dominguez, Paula Mera, Irma Garcia-Martinez, Elsa Maymó-Masip, Diana Grajales, Rosa Alen, Alfonso Mora, Neira Sáinz, Irene Vides-Urrestarazu, Nuria Vilarrasa, José M. Arbones-Mainar, Carlos Zaragoza, María J. Moreno-Aliaga, Patricia Aspichueta, Sonia Fernández-Veledo, Joan Vendrell, Dolors Serra, Laura Herrero, Renate Schreiber, Rudolf Zechner, Guadalupe Sabio, David Hornigold, Cristina M. Rondinone, Lutz Jermutus, Joseph Grimsby, Ángela M. Valverde
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Bariatric surgery is effective for the treatment and remission of obesity and type 2 diabetes, but pharmacological approaches which exert similar metabolic adaptations are needed to avoid post-surgical complications. Here we show how G49, an
Externí odkaz:
https://doaj.org/article/6e46df4151b04affa21678e1243d004d
Autor:
Patricia Rada, Elena Carceller-López, Ana B. Hitos, Beatriz Gómez-Santos, Constanza Fernández-Hernández, Esther Rey, Julia Pose-Utrilla, Carmelo García-Monzón, Águeda González-Rodríguez, Guadalupe Sabio, Antonia García, Patricia Aspichueta, Teresa Iglesias, Ángela M. Valverde
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102045- (2024)
Objectives: Protein kinase D (PKD) family is emerging as relevant regulator of metabolic homeostasis. However, the precise role of PKD2 in modulating hepatic insulin signaling has not been fully elucidated and it is the aim of this study. Methods: PK
Externí odkaz:
https://doaj.org/article/abf0bce88beb4a23b4cb4540fea29630
Autor:
María C. Ruiz-Aracil, Fabián Guillén, Salvador Castillo, Domingo Martínez-Romero, Juan M. Valverde
Publikováno v:
Agriculture, Vol 14, Iss 11, p 2040 (2024)
Tomatoes have a short shelf life, and refrigeration is commonly used to extend tomato quality. However, suboptimal temperatures can lead to chilling injury (CI), reducing their marketability. In this study, the combined application of 10 mM γ-aminob
Externí odkaz:
https://doaj.org/article/bca21e3447ed485d94a94bf2fd295a44
Autor:
Patricia Marañón, Esther Rey, Stephania C. Isaza, Hanghang Wu, Patricia Rada, Carmen Choya-Foces, Antonio Martínez-Ruiz, María Ángeles Martín, Sonia Ramos, Carmelo García-Monzón, Francisco Javier Cubero, Ángela M. Valverde, Águeda González-Rodríguez
Publikováno v:
Redox Biology, Vol 71, Iss , Pp 103088- (2024)
Acetaminophen (APAP)-induced liver injury is one of the most prevalent causes of acute liver failure (ALF). We assessed the role of the bone morphogenetic protein (BMP) type I receptors ALK2 and ALK3 in APAP-induced hepatotoxicity. The molecular mech
Externí odkaz:
https://doaj.org/article/dfecb0de4ea14159adf701f783671f60
Publikováno v:
European Psychiatry, Vol 67, Pp S533-S533 (2024)
Introduction Depressive disorders represent the main cause of disability in the world, due to its prevalence, its impact on the patient’s quality of life and its role as one of the main risk factors for suicide. Current antidepressant treatments ca
Externí odkaz:
https://doaj.org/article/ea045fe655c4431fa6b11a117d2f3d44
Publikováno v:
European Psychiatry, Vol 67, Pp S433-S433 (2024)
Introduction Manic episodes have a multifactorial etiology, with frequent association with genetic factors, comorbidities such as systemic diseases or secondary to infectious diseases, and environmental exposure factors. The prevalence of bipolar dis
Externí odkaz:
https://doaj.org/article/bd28db19a0ac463e9fed0f1a44003790
Autor:
Demilade Adedinsewo, MD, Jennifer Dugan, BA, Patrick W. Johnson, MS, Erika J. Douglass, DrPH, Andrea Carolina Morales-Lara, MD, Mark A. Parkulo, MD, Henry H. Ting, MD, Leslie T. Cooper, MD, Luis R. Scott, MD, Arturo M. Valverde, MD, Deepak Padmanabhan, MBBS, Nicholas S. Peters, MD, Patrik Bachtiger, MBBS, Mihir Kelshiker, MBBS, Francisco Fernandez-Aviles, MD, Felipe Atienza, MD, Taya V. Glotzer, MD, Marc K. Lahiri, MD, Paari Dominic, MD, Zachi I. Attia, PhD, Suraj Kapa, MD, Peter A. Noseworthy, MD, Naveen L. Pereira, MD, Jessica Cruz, MBA, Elie F. Berbari, MD, Rickey E. Carter, PhD, Paul A. Friedman, MD
Publikováno v:
Mayo Clinic Proceedings: Digital Health, Vol 1, Iss 4, Pp 455-466 (2023)
Objective: To evaluate the ability of a neural network to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using point-of-care electrocardiography obtained with a portable device. Patient and Methods: We enrolled 2827 p
Externí odkaz:
https://doaj.org/article/70df8238488d417d98aee85d5f6a403d
Autor:
Raquel Fernández-Ginés, José Antonio Encinar, Maribel Escoll, Daniel Carnicero-Senabre, José Jiménez-Villegas, Ángel J. García-Yagüe, Águeda González-Rodríguez, Irma Garcia-Martinez, Ángela M Valverde, Ana I. Rojo, Antonio Cuadrado
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103027- (2024)
Non-alcoholic steatohepatitis (NASH) is a common chronic liver disease that compromises liver function, for which there is not a specifically approved medicine. Recent research has identified transcription factor NRF2 as a potential therapeutic targe
Externí odkaz:
https://doaj.org/article/55f0658f6cd7407d98a9c86477d2e394
Autor:
Patricia Marañón, Stephania C. Isaza, Carlos Ernesto Fernández-García, Esther Rey, Rocío Gallego-Durán, Rocío Montero-Vallejo, Javier Rodríguez de Cía, Javier Ampuero, Ángela M. Valverde, Manuel Romero-Gómez, Carmelo García-Monzón, Águeda González-Rodríguez
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background & Aims Advanced hepatic fibrosis is the main risk factor of liver-related morbidity and mortality in patients with chronic liver disease. In this study, we assessed the potential role of bone morphogenetic protein 8A (BMP8A) as a
Externí odkaz:
https://doaj.org/article/8bdf154a44f54c48aa9adb7e918626e3
Autor:
Laura M. Laiglesia, Xavier Escoté, Neira Sáinz, Elisa Felix-Soriano, Eva Santamaría, María Collantes, Marta Fernández-Galilea, Ignacio Colón-Mesa, Leyre Martínez-Fernández, Tania Quesada-López, Sergio Quesada-Vázquez, Carlos Rodríguez-Ortigosa, José M. Arbones-Mainar, Ángela M. Valverde, J Alfredo Martínez, Jesmond Dalli, Laura Herrero, Silvia Lorente-Cebrián, Francesc Villarroya, María J. Moreno-Aliaga
Publikováno v:
Molecular Metabolism, Vol 74, Iss , Pp 101749- (2023)
Objective: Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (
Externí odkaz:
https://doaj.org/article/22820310ff864737969835f5345a7e5e