Zobrazeno 1 - 10
of 224
pro vyhledávání: '"M, Unni"'
Autor:
Dylan A. Farnsworth, Yusuke Inoue, Fraser D. Johnson, Georgia de Rappard-Yuswack, Daniel Lu, Rocky Shi, Lok In Josephine Ma, Marissa S. Mattar, Romel Somwar, Marc Ladanyi, Arun M. Unni, William W. Lockwood
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-15 (2022)
Abstract MEK inhibitors (MEKi) have limited efficacy in KRAS mutant lung adenocarcinoma (LUAD) patients, and this is attributed to both intrinsic and adaptive mechanisms of drug resistance. While many studies have focused on the former, there remains
Externí odkaz:
https://doaj.org/article/d1bc38b675aa48b9b89c98c59ec5707a
Autor:
Etienne S. Melese, Elizabeth Franks, Rachel A. Cederberg, Bryant T. Harbourne, Rocky Shi, Brennan J. Wadsworth, Jenna L. Collier, Elizabeth C. Halvorsen, Fraser Johnson, Jennifer Luu, Min Hee Oh, Vivian Lam, Gerald Krystal, Shelley B. Hoover, Mark Raffeld, R. Mark Simpson, Arun M. Unni, Wan L. Lam, Stephen Lam, Ninan Abraham, Kevin L. Bennewith, William W. Lockwood
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Current immunotherapies for lung cancer are only effective in a subset of patients. Identifying tumor-derived factors that facilitate immunosuppression offers the opportunity to develop novel strategies to supplement and improve current therapeutics.
Externí odkaz:
https://doaj.org/article/2c2a00203bef4e89885342925d64134f
Autor:
Shijina Kottarathil, Sreekanth Narayanaru, Sreekuttan M. Unni, Takanori Tamaki, Hidenori Kuroki, Unnikrishnan Nair Saraswathy Hareesh, Gopinathan M. Anilkumar, Takeo Yamaguchi
Publikováno v:
ACS Applied Energy Materials. 5:12571-12582
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a626c39cdf746b0d2eae4cd4fd1eac4
https://doi.org/10.1021/acsaem.2c02133
https://doi.org/10.1021/acsaem.2c02133
Publikováno v:
Renewable Energy Technologies. :375-402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1cf2454a89c3bd45a10127e600e66c
https://doi.org/10.1002/9781119827634.ch11
https://doi.org/10.1002/9781119827634.ch11
Autor:
Katerina Politi, Darren A.E. Cross, Paul D. Smith, Mark A. Lemmon, Sarah B. Goldberg, Franziska Michor, William W. Lockwood, Robert Homer, Arun M. Unni, Susan M. Kaech, Alexandra Kuhlmann, Tyler F. Stewart, Deborah Ayeni, Mmaserame Gaefele, Kumar Dilip Ashtekar, Hina Khan, Kristin S. Price, Dylan Farnsworth, Amy Nagelberg, Iris K. van Alderwerelt van Rosenburgh, Kamrine E. Poels, Maria Emanuela Cuomo, Alexis A. Guernet, Jacqueline H. Starrett
Osimertinib, a mutant-specific third-generation EGFR tyrosine kinase inhibitor, is emerging as the preferred first-line therapy for EGFR-mutant lung cancer, yet resistance inevitably develops in patients. We modeled acquired resistance to osimertinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020e6dd47591fa2fba8059b795f05a5d
https://doi.org/10.1158/0008-5472.c.6511554
https://doi.org/10.1158/0008-5472.c.6511554
Autor:
Katerina Politi, Darren A.E. Cross, Paul D. Smith, Mark A. Lemmon, Sarah B. Goldberg, Franziska Michor, William W. Lockwood, Robert Homer, Arun M. Unni, Susan M. Kaech, Alexandra Kuhlmann, Tyler F. Stewart, Deborah Ayeni, Mmaserame Gaefele, Kumar Dilip Ashtekar, Hina Khan, Kristin S. Price, Dylan Farnsworth, Amy Nagelberg, Iris K. van Alderwerelt van Rosenburgh, Kamrine E. Poels, Maria Emanuela Cuomo, Alexis A. Guernet, Jacqueline H. Starrett
Cell-free DNA Mutation Dataset
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e087b2fda02e3e7f2fdd7bb134ea395
https://doi.org/10.1158/0008-5472.22423677
https://doi.org/10.1158/0008-5472.22423677
Autor:
Katerina Politi, Darren A.E. Cross, Paul D. Smith, Mark A. Lemmon, Sarah B. Goldberg, Franziska Michor, William W. Lockwood, Robert Homer, Arun M. Unni, Susan M. Kaech, Alexandra Kuhlmann, Tyler F. Stewart, Deborah Ayeni, Mmaserame Gaefele, Kumar Dilip Ashtekar, Hina Khan, Kristin S. Price, Dylan Farnsworth, Amy Nagelberg, Iris K. van Alderwerelt van Rosenburgh, Kamrine E. Poels, Maria Emanuela Cuomo, Alexis A. Guernet, Jacqueline H. Starrett
Supplementary Methods, Supplementary Tables S1-5, and Supplementary Figures S1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02dd4a06b12d851a1a5507ab39dac7f9
https://doi.org/10.1158/0008-5472.22423680
https://doi.org/10.1158/0008-5472.22423680
Autor:
Arun M Unni, Bryant Harbourne, Min Hee Oh, Sophia Wild, John R Ferrarone, William W Lockwood, Harold Varmus
Publikováno v:
eLife, Vol 7 (2018)
Synthetic lethality results when mutant KRAS and EGFR proteins are co-expressed in human lung adenocarcinoma (LUAD) cells, revealing the biological basis for mutual exclusivity of KRAS and EGFR mutations. We have now defined the biochemical events re
Externí odkaz:
https://doaj.org/article/c9a152b7e5fb4105b4de838a7f359c26
Autor:
Jean-Philippe Theurillat, Tiziano Bernasocchi, Francesco Bertoni, Arun M. Unni, Mark A. Rubin, Geniver El Tekle, Davide Rossi
Publikováno v:
Trends in Cancer. 7:823-836
Cancer is the dysregulated proliferation of cells caused by acquired mutations in key driver genes. The most frequently mutated driver genes promote tumorigenesis in various organisms, cell types, and genetic backgrounds. However, recent cancer genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3b6655f3e3ed9e2db0a74dfae3c9fa
https://doi.org/10.1016/j.trecan.2021.04.009
https://doi.org/10.1016/j.trecan.2021.04.009
Autor:
Sreekuttan M. Unni, Avanish Shukla, Santoshkumar D. Bhat, Nagaraju Niluroutu, Vishal M. Dhavale
Publikováno v:
International Journal of Hydrogen Energy. 46:20640-20649
A composite membrane comprising sulfonated polyether ether ketone (sPEEK) and polystyrene sulfonic acid functionalized micelle templated MCM-41 (PSSA-f-MCM-41) is realized as a potential alternative to the Nafion membrane for direct methanol fuel cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12887f81fb3af8e54782ac566f24b960
https://doi.org/10.1016/j.ijhydene.2021.03.156
https://doi.org/10.1016/j.ijhydene.2021.03.156