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Expression of tissue factor in canine mammary tumours and correlation with grade, stage and markers of haemostasis and inflammation

Autor: E B, Andreasen, O L, Nielsen, M, Tranholm, T, Knudsen, A T, Kristensen

Publikováno v: Veterinary and comparative oncology. 14(2)

Tissue factor (TF) expression in human cancers has been associated with a procoagulant state and facilitation of metastasis. This study was conducted in order to evaluate if TF was expressed in canine mammary tumours. Forty epithelial mammary tumours

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a0e5441085158268640f77a7f6a38f1e
https://pubmed.ncbi.nlm.nih.gov/24674618

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A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate(®))

Autor: A E, Pastoft, J, Lykkesfeldt, M, Ezban, M, Tranholm, H C, Whinna, B, Lauritzen

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 18(5)

Haemostatic effect of compounds for treating haemophilia can be evaluated in various bleeding models in haemophilic mice. However, the doses of factor VIII (FVIII) for normalizing bleeding used in some of these models are reported to be relatively hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::afa380036d4251bb79046bebccc7e221
https://pubmed.ncbi.nlm.nih.gov/22500820

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Pharmacokinetics and pharmacodynamics of a new recombinant FVIII (N8) in haemophilia A mice

Autor: T, Elm, D M, Karpf, K, Øvlisen, H, Pelzer, M, Ezban, M, Kjalke, M, Tranholm

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 18(1)

N8 is a new recombinant factor VIII (rFVIII) compound produced and formulated without human- or animal-derived protein. The aims of the present studies were to evaluate the pharmacokinetics and pharmacodynamics properties of N8 and to compare with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a9dea00dd70cd60a9e68aef08ec55bf4
https://pubmed.ncbi.nlm.nih.gov/21771205

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