Výsledky vyhledávání

Circling behavior exhibited by a transgenic insertional mutant

Autor: A K, Ratty, L W, Fitzgerald, M, Titeler, S D, Glick, J J, Mullins, K W, Gross

Publikováno v: Brain research. Molecular brain research. 8(4)

We report here of an abnormal circling behavior expressed in the TgX15 transgenic mouse line as a result of insertional mutagenesis. Homozygous transgenic mice expressed the phenotype while heterozygous transgenics were normal. We also found that the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444f3ee7ca0aa9171c8a547e76bd7856
https://pubmed.ncbi.nlm.nih.gov/1980140

Zobrazit plný text záznamu

D2 dopamine receptors modulate calcium channel currents and catecholamine secretion in bovine adrenal chromaffin cells

Autor: L, Bigornia, C N, Allen, C R, Jan, R A, Lyon, M, Titeler, A S, Schneider

Publikováno v: The Journal of pharmacology and experimental therapeutics. 252(2)

Although dopamine is known to be present in sympathetic ganglia, its role and mode of action as a peripheral neurotransmitter are still poorly understood. Dopaminergic agonists have been shown to inhibit adrenal catecholamine release and calcium upta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2075acd7ecb8c7c00117258d2466e4fb
https://pubmed.ncbi.nlm.nih.gov/2156054

Zobrazit plný text záznamu

Antiparkinsonian drug doses and neuroleptic receptors

Autor: Philip Seeman, M. Titeler

Publikováno v: Experientia. 34:1490-1492

The clinical potency of 3 drugs, apomorphine, N-propylnorapomorphine, and bromocryptine, have been found to be closely correlated to their potencies in competing for 3H-haloperidol and 3H-spiroperidol both of which label the dopamine receptor. This c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0459423abe4e57dee888c4647065e8
https://doi.org/10.1007/bf01932371

Zobrazit plný text záznamu

Initial detection of [3H]prazosin-labeled alpha 1-receptors in the porcine pituitary neurointermediate lobe

Autor: G, Battaglia, M, Shannon, M, Titeler

Publikováno v: Molecular pharmacology. 24(3)

[3H]Prazosin binding to alpha 1-adrenergic receptors was investigated in homogenates of tissue from the porcine pituitary neurointermediate lobe. Potent alpha 1-adrenergic antagonists such as prazosin, WB-4101, and phentolamine displayed high potency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bf09f9b1049b21602d60dd27af54a01d
https://pubmed.ncbi.nlm.nih.gov/6138705

Zobrazit plný text záznamu

Selective labeling of α-adrenergic receptors in caudate nucleus by [3H]dihydroergocryptine in the presence of spiperone-blocked dopamine receptors

Autor: P. Seeman, M. Titeler

Because it was known that [ 3 H]dihydroergocryptine can label α-adrenergic receptors as well as dopamine receptors, this study was done to establish the conditions under which [ 3 H]dihydroergocryptine would be a reliable ligand for selective labeli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4d5b9e34b96c71c9180245d7c4be97
https://europepmc.org/articles/PMC392529/

Zobrazit plný text záznamu

Selectivity of serotonergic drugs for multiple brain serotonin receptors. Role of [3H]-4-bromo-2,5-dimethoxyphenylisopropylamine ([3H]DOB), a 5-HT2 agonist radioligand

Autor: M, Titeler, R A, Lyon, K H, Davis, R A, Glennon

Publikováno v: Biochemical pharmacology. 36(19)

The affinities of putative serotonin receptor agonists and antagonists for 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT2 receptors were assayed using radioligand binding assays. The 5-HT1 sites were labeled with the agonist radioligands [3H]-8-hydroxy-2-(di-n-pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3da887429dc5c3114c4e82a0882cdac
https://pubmed.ncbi.nlm.nih.gov/3663239

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání