Výsledky vyhledávání

Robust Immune Response Induced by Schistosoma mansoni TSP-2 Antigen Coupled to Bacterial Outer Membrane Vesicles

Autor: Mariana I. Khouri, Violeta Pancakova, Dunia Rodriguez, Jessica Lobo-Silva, Richard Malley, Martha M. Tanizaki, Rocilda P.F. Schenkman, Eliana L. Faquim-Mauro, Amanda P Freitas, Leonardo P. Farias, Diana Boraschi, Mayra M.F. Barbosa, Monalisa M Trentini, Giovana Cappio Barazzone, Viviane Maimoni Gonçalves, Luciana C. C. Leite, Alex I. Kanno

Publikováno v: International Journal of Nanomedicine. 16:7153-7168

Mayra M F Barbosa,1,2 Alex I Kanno,1 Giovana C Barazzone,1 Dunia Rodriguez,1 Violeta Pancakova,1,3 Monalisa Trentini,1 Eliana L Faquim-Mauro,4 Amanda P Freitas,4 Mariana I Khouri,5 Jessica Lobo-Silva,5 Viviane M Goncalves,1 Rocilda P F Schenkman,1 Ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c1157a3e59793110c7006e40f008787
https://doi.org/10.2147/ijn.s315786

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Akademický článek

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Robust Immune Response Induced by

Autor: Mayra M F, Barbosa, Alex I, Kanno, Giovana C, Barazzone, Dunia, Rodriguez, Violeta, Pancakova, Monalisa, Trentini, Eliana L, Faquim-Mauro, Amanda P, Freitas, Mariana I, Khouri, Jessica, Lobo-Silva, Viviane M, Goncalves, Rocilda P F, Schenkman, Martha M, Tanizaki, Diana, Boraschi, Richard, Malley, Leonardo P, Farias, Luciana C C, Leite

Publikováno v: International Journal of Nanomedicine

Purpose The use of adjuvants can significantly strengthen a vaccine’s efficacy. We sought to explore the immunization efficacy of bacterial outer membrane vesicles (OMVs) displaying the Schistosoma mansoni antigen, SmTSP-2, through a biotin-rhizavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14b7d0a04f69b755e9716a5d56182037
https://pubmed.ncbi.nlm.nih.gov/34712047

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Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

Autor: Giovana Cappio Barazzone, Martha M. Tanizaki, Luciana C. C. Leite, T.R. Converso, Viviane Maimoni Gonçalves, Miriam A. Silva

Publikováno v: Clinical and Vaccine Immunology. 24

Current pneumococcal vaccines are composed of bacterial polysaccharides as antigens, plain or conjugated to carrier proteins. While efficacious against vaccine serotypes, epidemiologic data show an increasing incidence of infections caused by nonvacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d77ceb160110c668bbe6fca91c23894
https://doi.org/10.1128/cvi.00118-17

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Experimental design and metabolic flux analysis tools to optimize industrially relevant Haemophilus influenzae type b growth medium

Autor: Carla Andreia Freixo Portela, Martha M. Tanizaki, Mateus Ribeiro da Silva, Paola Rizzo de Paiva, Silvia Maria Ferreira Albani, Teresa Cristina Zangirolami

Publikováno v: Biotechnology progress. 33(6)

Haemophilus influenzae type b (Hib), a Gram-negative capsulated bacterium, is a causative agent of meningitis worldwide. The capsular polysaccharide, a high molecular mass polymer consisting of the repeated units of the polyribosyl-ribitol-phosphate,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5683ee44cedc55d00f662493c658ef3e
https://pubmed.ncbi.nlm.nih.gov/28840658

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On-line prediction of the feeding phase in high-cell density cultivation of rE. coli using constructive neural networks

Autor: Martha M. Tanizaki, Antonio Carlos Luperni Horta, Viviane Maimoni Gonçalves, Teresa Cristina Zangirolami, Roberto C. Giordano, João Roberto Bertini, Maria do Carmo Nicoletti

Publikováno v: Computer Methods and Programs in Biomedicine. 111:228-248

Streptococcus pneumoniae (pneumococcus) is a bacterium responsible for a wide spectrum of illnesses. The surface of the bacterium consists of three distinctive membranes: plasmatic, cellular and the polysaccharide (PS) capsule. PS capsules may mediat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8941820e98904981f3bb6dc85179b2a
https://doi.org/10.1016/j.cmpb.2013.03.005

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Development of production and purification processes of recombinant fragment of pneumococcal surface protein A in Escherichia coli using different carbon sources and chromatography sequences

Autor: Joaquin Cabrera-Crespo, Viviane Maimoni Gonçalves, Martha M. Tanizaki, Rimenys Junior Carvalho

Publikováno v: Applied Microbiology and Biotechnology. 94:683-694

Pneumococcal surface protein A (PspA) is essential for Streptococcus pneumoniae virulence and its use either as a novel pneumococcal vaccine or as carrier in a conjugate vaccine would improve the protection and the coverage of the vaccine. Within thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2d29c3bb953bf10f2e635913092578
https://doi.org/10.1007/s00253-011-3649-9

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Production and purification of recombinant fragment of pneumococcal surface protein A (PspA) in Escherichia coli

Autor: Adilson José da Silva, Cintia Regina Sargo, Luciana C. C. Leite, Antonio Carlos Luperni Horta, Viviane Maimoni Gonçalves, Teresa Cristina Zangirolami, Cibelly Goulart, Rimenys Jr. Carvalho, Stefanie Kraschowetz, Giovana Cappio Barazzone, Joaquin Cabrera-Crespo, Martha M. Tanizaki

Publikováno v: Procedia in Vaccinology. 4:27-35

New conjugated vaccines against Streptococcus pneumoniae are being developed using pneumococcal surface proteins as carriers. The pneumococcal surface protein A (PspA) was selected as carrier because it is indispensable for virulence of S. pneumoniae

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea188d037586d65f07240e139c14eea

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Purification of capsular polysaccharide produced by Haemophilus influenzae type b through a simple, efficient and suitable method for scale-up

Autor: Silvia Maria Ferreira Albani, Mickie Takagi, Teresa Cristina Zangirolami, Joaquin Cabrera-Crespo, Rodrigo Barbosa Lima, Martha M. Tanizaki

Publikováno v: Journal of Industrial Microbiology & Biotechnology. 35:1217-1222

Haemophilus influenzae type b, an encapsulated bacterium, causes meningitis in infants worldwide. The capsular polysaccharide conjugated to a carrier protein is effective in the prevention of such infections. The traditional purification process of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b8b4f59f432e307b474cee75e62faf8
https://doi.org/10.1007/s10295-008-0428-4

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Protection induced by pneumococcal surface protein A (PspA) is enhanced by conjugation to a Streptococcus pneumoniae capsular polysaccharide

Autor: Michelle Darrieux, Martha M. Tanizaki, Joaquim Cabrera-Crespo, Viviane Maimoni Gonçalves, Mickie Takagi, M. E. Sbrogio-Almeida, Fátima C.L. Csordas, Luciana C. C. Leite, Catia T. Perciani

Publikováno v: Vaccine. 26:2925-2929

The currently available anti-pneumococcal vaccines are based on capsular polysaccharide (PS), plain or conjugated to a carrier protein. Conjugated vaccines are expensive products, especially in the case of pneumococcus, in which reasonable coverage r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebab7e0090c7a2b0a0e270d234dcce2
https://doi.org/10.1016/j.vaccine.2008.03.038

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