Zobrazeno 1 - 10
of 460
pro vyhledávání: '"M, Sturek"'
Autor:
Barbara J. Mann, Preeti Chhabra, Mingyang Ma, Savannah G. Brovero, Riley T. Hannan, Jeffrey M. Sturek, Marieke K. Jones, Joel Linden, Kenneth L. Brayman
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e19226- (2023)
A life-threatening manifestation of Covid-19 infection is a cytokine storm that requires hospitalization and supplemental oxygen. Various strategies to reduce inflammatory cytokines have had some success in limiting cytokine storm and improving survi
Externí odkaz:
https://doaj.org/article/cb65da4a2fdd4466b16b1daa0681bba3
Autor:
Mayuresh M. Abhyankar, Barbara J. Mann, Jeffrey M. Sturek, Savannah Brovero, G. Brett Moreau, Anjali Sengar, Crystal M. Richardson, Sayeh Agah, Anna Pomés, Peter M. Kasson, Mark A. Tomai, Christopher B. Fox, William A. Petri
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations pr
Externí odkaz:
https://doaj.org/article/da4da1c7c88a4956b31769225afbc2c2
Autor:
Andrea R. Daamen, Prathyusha Bachali, Catherine A. Bonham, Lindsay Somerville, Jeffrey M. Sturek, Amrie C. Grammer, Alexandra Kadl, Peter E. Lipsky
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
COVID-19 manifests a spectrum of respiratory symptoms, with the more severe often requiring hospitalization. To identify markers for disease progression, we analyzed longitudinal gene expression data from patients with confirmed SARS-CoV-2 infection
Externí odkaz:
https://doaj.org/article/ae274b8bfc5f481298507a3548f53215
Autor:
Jeffrey M. Sturek, Tania A. Thomas, James D. Gorham, Chelsea A. Sheppard, Allison H. Raymond, Kristen Petros De Guex, William B. Harrington, Andrew J. Barros, Gregory R. Madden, Yosra M. Alkabab, David Y. Lu, Qin Liu, Melinda D. Poulter, Amy J. Mathers, Archana Thakur, Dana L. Schalk, Ewa M. Kubicka, Lawrence G. Lum, Scott K. Heysell
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an unprecedented event requiring frequent adaptation to changing clinical circumstances. Convalescent immune plasma (CIP) is a promising trea
Externí odkaz:
https://doaj.org/article/9c79a21b9c364848a5066e1655b6206b
Autor:
Alexandra N. Donlan, Tara E. Sutherland, Chelsea Marie, Saskia Preissner, Benjamin T. Bradley, Rebecca M. Carpenter, Jeffrey M. Sturek, Jennie Z. Ma, G. Brett Moreau, Jeffrey R. Donowitz, Gregory A. Buck, Myrna G. Serrano, Stacey L. Burgess, Mayuresh M. Abhyankar, Cameron Mura, Philip E. Bourne, Robert Preissner, Mary K. Young, Genevieve R. Lyons, Johanna J. Loomba, Sarah J. Ratcliffe, Melinda D. Poulter, Amy J. Mathers, Anthony J. Day, Barbara J. Mann, Judith E. Allen, William A. Petri Jr.
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection. Understanding the mechanisms by which the immune system contributes to COVID-19 severity may open new avenues to treatment. Here, we report that elevated IL-13
Externí odkaz:
https://doaj.org/article/a6c6e0e467c54cfc87c0eba3f4b21036
Autor:
Bibo Zhu, Xiaoqin Wei, Harish Narasimhan, Wei Qian, Ruixuan Zhang, In Su Cheon, Yue Wu, Chaofan Li, Russell G. Jones, Mark H. Kaplan, Robert A. Vassallo, Thomas J. Braciale, Lindsay Somerville, Jerry R. Colca, Akhilesh Pandey, Patrick E. H. Jackson, Barbara J. Mann, Connie M. Krawczyk, Jeffrey M. Sturek, Jie Sun
Publikováno v:
Science Immunology. 8
The relationship between diabetes and coronavirus disease 2019 (COVID-19) is bidirectional: Although individuals with diabetes and high blood glucose (hyperglycemia) are predisposed to severe COVID-19, severe acute respiratory syndrome coronavirus 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800b834d23f8113579787e11ecef687d
https://doi.org/10.1126/sciimmunol.adf0348
https://doi.org/10.1126/sciimmunol.adf0348
Publikováno v:
Annals of the American Thoracic Society. 19:1946-1948
Light’s criteria is the standard for determining the etiology of pleural effusions. Test characteristics of Light’s criteria varies in different populations, and Light’s criteria may misclassify effusions in patients with impaired immunity such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c79ab7fecbf8ac95876740b1e6da0d
https://doi.org/10.1513/annalsats.202204-331rl
https://doi.org/10.1513/annalsats.202204-331rl
Autor:
Thomas S. Valley, Amanda Schutz, Ithan D. Peltan, Kelly C. Vranas, Kusum S. Mathews, Sarah E. Jolley, Jessica A. Palakshappa, Catherine L. Hough, Jay S. Steingrub, Mark A. Tidswell, Lori-Ann Kozikowski, Cynthia Kardos, Lesley DeSouza, Rebecca M. Baron, Mayra Pinilla-Vera, David M. Rubins, Antonio Arciniegas, Richard Riker, Christine Lord, Marie-Carmelle Elie, Daniel Talmor, Nathan Shapiro, Valerie Banner-Goodspeed, Kathryn A. Hibbert, Kelsey Brait, Natalie Pulido, Alan Jones, James Galbraith, Utsav Nandi, Rebekah Peacock, Jenna Davis, Matthew Prekker, Michael Puskarich, Seth Jones, Anne Roerhl, Audrey Hendrickson, Michael Matthay, Kirsten Kangelaris, Kathleen Liu, Kimberly Yee, Hanjing Zhuo, Gregory Hendey, Steven Chang, Nida Qadir, Andrea Tam, Rebecca Beutler, Trisha Agarwal, Joseph Levitt, Jennifer G. Wilson, Angela Rogers, Jonasel Roque, Rosemary Vojnik, Timothy E. Albertson, James A. Chenoweth, Jason Y. Adams, Brian M. Morrissey, Skyler J. Pearson, Eyad Almasri, Alyssa Hughes, Marc Moss, Adit Ginde, Jeffrey McKeehan, Lani Finck, Michelle Howell, Carrie Higgins, Jason Haukoos, Stephanie Gravitz, Carolynn Lyle, Ivor S. Douglas, Terra Hiller, Audrey Goold, James Finigan, Robert Hyzy, Pauline Park, Michael Sjoding, Stephen Kay, Kristine Nelson, Kelli McDonough, Namita Jayaprakash, Emanuel P. Rivers, Jennifer Swiderek, Jasreen Kaur Gill, Jacqueline Day, Robert Sherwin, James Wooden, Thomas Mazzoco, Michelle Ng Gong, Michael Aboodi, Ayesha Asghar, Omowunmi Amosu, Hiwet Tzehaie, Aluko A. Hope, Jen-Ting Chen, Rahul Nair, Brenda Lopez, Obiageli Offor, Jarrod M. Mosier, Cameron D. Hypes, Elizabeth Salvagio, Christian Bime, Elaine Cristan, Lynne D. Richardson, Neha Goel, Patrick Maher, Samuel Acquah, Donald Cardone, Gary Oldenburg, Andrew Dunn, Duncan Hite, Kristin Hudock, Jose Gomez Arroyo, Tammy Roads, Abhijit Duggal, Eduardo Mireles-Cabodevila, Bryce R.H. Robinson, Nicholas J. Johnson, Stephanie Gundel, Laura Evans, D. Shane O'Mahony, Julie A. Wallick, Isabel Pedraza, Akram Khan, Olivia Krol, Milad Karami Jouzestani, Kelly Vranas, Donald M. Yealy, Derek C. Angus, Alexandra Weissman, David T. Huang, Aimee Boeltz-Skrtich, Steven Moore, Derek Isenberg, D. Clark Files, Chadwick Miller, Kevin Gibbs, Lori Flores, Mary LaRose, Lauren Koehler, Leigha Landreth, Peter Morris, Evan Cassity, Jamie Sturgill, Kirby Mayer, Ashley Montgomery-Yates, Marjolein de Wit, Jessica Mason, Andrew Goodwin, Abigail Grady, Patterson Burch, Kyle B. Enfield, Jeffrey M. Sturek, Mary Marshall, Joseph R. Bledsoe, Samuel M. Brown, Colin K. Grissom, Brent Armbruster, Estelle Harris, John Eppensteiner, Bria Johnston Hall, Grace L. Hall, Lauren McGowan, Andrew Bouffler, Erica Walker, Samuel Francis, Tedra Porter, Bennett P. deBoisblanc, Matthew R. Lammi, David R. Janz, Paula Lauto, Connie Romaine, Marie Sandi, Todd W. Rice, Wesley H. Self, Nancy Ringwood, Alexander Nagrebetsky, Laura Fitzgerald, Roy G. Brower, Lora A. Reineck, Neil R. Aggarwal, Karen Bienstock
Publikováno v:
Chest. 161:1485-1489
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ce498b19405c1199f0b011c47227c4
https://doi.org/10.1016/j.chest.2022.01.034
https://doi.org/10.1016/j.chest.2022.01.034
Autor:
Jennifer, Sasson, Alexandra N, Donlan, Jennie Z, Ma, Heather M, Haughey, Rachael, Coleman, Uma, Nayak, Amy J, Mathers, Sylvain, Laverdure, Robin, Dewar, Patrick E H, Jackson, Scott K, Heysell, Jeffrey M, Sturek, William A, Petri
Publikováno v:
Open Forum Infectious Diseases. 9
Background Based on studies implicating the type 2 cytokine interleukin 13 (IL-13) as a potential contributor to critical coronavirus disease 2019 (COVID-19), this trial was designed as an early phase 2 study to assess dupilumab, a monoclonal antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acddeef78c9e0a1f28b5868e0fea7ced
https://doi.org/10.1093/ofid/ofac343
https://doi.org/10.1093/ofid/ofac343
Autor:
Jeffrey M. Sturek, Coleen A. McNamara, Behnam Keshavarz, Judith A. Woodfolk, Thomas A.E. Platts-Mills, Lyndsey M. Muehling, Glenda Canderan, Joesph R Wiencek, Lisa J. Workman, Matthew Straesser, Chintan Ramani, Alexandra Kadl, Jeffrey M. Wilson, Catherine A. Bonham, Fabrizio Drago
Publikováno v:
medRxiv
Background: Detailed understanding of the immune response to severe acute respiratory syndrome coronavirus (SARS-CoV)-2, the cause of coronavirus disease 2019 (COVID-19) has been hampered by a lack of quantitative antibody assays. Objective: The ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051118a5a3bce97f5b193b9b47523f00
https://doi.org/10.1159/000514203
https://doi.org/10.1159/000514203