Zobrazeno 1 - 10
of 594
pro vyhledávání: '"M, Stemmer"'
Autor:
Pankaj Bhatia, Shomaila Mehmood, Nicole Doyon-Reale, Rita Rosati, Paul M. Stemmer, Samson Jamesdaniel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
IntroductionExposure to heavy metal lead can cause serious health effects such as developmental neurotoxicity in infants, cognitive impairment in children, and cardiovascular and nephrotoxic effects in adults. Hearing loss is one of the toxic effects
Externí odkaz:
https://doaj.org/article/65562c36017b4f90840d21ab505ca44c
Autor:
Ofer Rotem, Karyn Revital Geiger, Ekaterina Hanovich, Mor Moskovitz, Noga Kurman, Daniel Reinhorn, Idit Peretz, Rinat Yerushalmi, Salomon M. Stemmer
Publikováno v:
Oncology Reviews, Vol 18 (2024)
As clinical trials in oncology require substantial efforts, maximizing the insights gained from them by conducting subgroup analyses is often attempted. The goal of these analyses is to identify subgroups of patients who are likely to benefit, as wel
Externí odkaz:
https://doaj.org/article/18f293ed166a48a39dded36cb9ce5bf3
Autor:
Shlomit S. Shachar, Michelle Leviov, Rinat Yerushalmi, Karen Drumea, Margarita Tokar, Lior Soussan-Gutman, Avital Bareket-Samish, Amir Sonnenblick, Noa Ben-Baruch, Ella Evron, Einav Nili Gal-Yam, Shani Paluch-Shimon, Gil Bar-Sela, Hadar Goldvaser, Salomon M. Stemmer
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-7 (2023)
Abstract Data on using the 21-gene Recurrence Score (RS) testing on second breast cancer (BC; second primary or local recurrence) are lacking. This cohort study examined patients with first and second BC, who underwent 21-gene testing both times. It
Externí odkaz:
https://doaj.org/article/3bcf6bdee0c84eafb59930d692223e0a
Publikováno v:
Case Reports in Obstetrics and Gynecology, Vol 2024 (2024)
Desmoid fibromatosis (DF) is a rare and locally aggressive neoplasm. We present a case of a 28-year-old previously healthy multigravida who noticed a lump in her abdomen near the umbilicus two months before becoming pregnant. It underwent rapid growt
Externí odkaz:
https://doaj.org/article/b0dd58177f2042658910c2af4c9579a8
Autor:
Ofer Rotem, Idit Peretz, Michelle Leviov, Iryna Kuchuk, Amit Itay, Margarita Tokar, Shani Paluch-Shimon, Ofra Maimon, Rinat Yerushalmi, Karen Drumea, Ella Evron, Amir Sonnenblick, Einav Gal-Yam, Hadar Goldvaser, Yosef Samih, Rotem Merose, Avital Bareket-Samish, Lior Soussan-Gutman, Salomon M. Stemmer
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Data on adjuvant chemotherapy (CT) benefit in ER + HER2‒ early-stage breast cancer (EBC) patients with Recurrence Score (RS) 26-30 are limited. This real-world study evaluated the relationships between the RS, adjuvant treatments, and outc
Externí odkaz:
https://doaj.org/article/ee418dc5761c458bb5099fc02f2cafa0
Autor:
James J. Harding, Sarina A. Piha-Paul, Ronak H. Shah, Jessica J. Murphy, James M. Cleary, Geoffrey I. Shapiro, David I. Quinn, Irene Braña, Victor Moreno, Mitesh Borad, Sherene Loi, Iben Spanggaard, Haeseong Park, James M. Ford, Mónica Arnedos, Salomon M. Stemmer, Christelle de la Fouchardiere, Christos Fountzilas, Jie Zhang, Daniel DiPrimeo, Casey Savin, S. Duygu Selcuklu, Michael F. Berger, Lisa D. Eli, Funda Meric-Bernstam, Komal Jhaveri, David B. Solit, Ghassan K. Abou-Alfa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
In biliary tract cancer HER2 alterations correlate with poor prognosis. Here, the authors present the results of a phase II clinical trial reporting the efficacy and safety of the tyrosine kinase inhibitor neratinib in patients with HER2-mutation pos
Externí odkaz:
https://doaj.org/article/6b0c6dc798b14d37bd9664bd41aec7e1
Autor:
Shira Perez, Anat Lavi-Itzkovitz, Moriah Gidoni, Tom Domovitz, Roba Dabour, Ishant Khurana, Ateret Davidovich, Ana Tobar, Alejandro Livoff, Evgeny Solomonov, Yaakov Maman, Assam El-Osta, Yishan Tsai, Ming-Lung Yu, Salomon M. Stemmer, Izhak Haviv, Gur Yaari, Meital Gal-Tanamy
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 63-81 (2023)
Background & Aims: Hepatocellular carcinoma (HCC) is a model of a diverse spectrum of cancers because it is induced by well-known etiologies, mainly hepatitis C virus (HCV) and hepatitis B virus. Here, we aimed to identify HCV-specific mutational sig
Externí odkaz:
https://doaj.org/article/2504d44cdec5437d864285de9108428c
Intrinsic sexual dimorphism in the placenta determines the differential response to benzene exposure
Autor:
Anthony Maxwell, Nicholas Adzibolosu, Anna Hu, Yuan You, Paul M. Stemmer, Douglas M. Ruden, Michael C. Petriello, Marianna Sadagurski, Lucas K. Debarba, Lisa Koshko, Jayanth Ramadoss, Annie Thy Nguyen, Darby Richards, Aihua Liao, Gil Mor, Jiahui Ding
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106287- (2023)
Summary: Maternal immune activation (MIA) by environmental challenges is linked to severe developmental complications, such as neurocognitive disorders, autism, and even fetal/maternal death. Benzene is a major toxic compound in air pollution that af
Externí odkaz:
https://doaj.org/article/07b2399baee443fd90afa6f11e1f4297
Autor:
Raz Mutai, Tamar Barkan, Assaf Moore, Michal Sarfaty, Tzippy Shochat, Rinat Yerushalmi, Salomon M. Stemmer, Hadar Goldvaser
Publikováno v:
Breast, Vol 60, Iss , Pp 62-69 (2021)
Background: Recent data suggest that human epidermal growth factor receptor 2 (HER2)-low breast cancer may represent a distinct entity. We aimed to compare disease characteristics and outcomes between HER2-low and HER2-0 in estrogen receptor (ER) pos
Externí odkaz:
https://doaj.org/article/c7b76536ee9b482e9a235ad0bc4badd8
Autor:
Chitra Thakur, Yiran Qiu, Qian Zhang, Nicholas J. Carruthers, Miaomiao Yu, Zhuoyue Bi, Yao Fu, Priya Wadgaonkar, Bandar Almutairy, Akimasa Seno, Paul M. Stemmer, Fei Chen
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105057- (2022)
Summary: In this report, we provide evidence showing diminished expression of the mineral dust-induced gene (mdig), a previously identified oncogenic gene, in human triple negative breast cancer (TNBC). Using a mouse model of orthotopic xenograft of
Externí odkaz:
https://doaj.org/article/1c2cbcbf074541f6a44b5dbfde9a3421