Zobrazeno 1 - 10
of 229
pro vyhledávání: '"M, Solon"'
Autor:
Samantha M. Solon-Biet, Ximonie Clark, Kim Bell-Anderson, Patricia M. Rusu, Ruth Perks, Therese Freire, Tamara Pulpitel, Alistair M. Senior, Andrew J. Hoy, Okka Aung, David G. Le Couteur, David Raubenheimer, Adam J. Rose, Arthur D. Conigrave, Stephen J. Simpson
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113536- (2023)
Summary: Fibroblast growth factor 21 (FGF21), an endocrine signal robustly increased by protein restriction independently of an animal’s energy status, exerts profound effects on feeding behavior and metabolism. Here, we demonstrate that considerin
Externí odkaz:
https://doaj.org/article/67b2b68aaa1d44e198ce08c2781e6b02
Autor:
Samantha M. Solon-Biet, Lucy Griffiths, Sophie Fosh, David G. Le Couteur, Stephen J. Simpson, Alistair M. Senior
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background The role of dietary branched chain amino acids (BCAAs) and their effect on metabolic health is complex. How dietary BCAA levels and their interaction with background nutrition affect health is unclear. Here, we used meta-analysis
Externí odkaz:
https://doaj.org/article/9aba48b7982f47f2a756a6c4bd886f16
Autor:
Valentina Rodriguez Paris, Xin Yi Denise Wong, Samantha M Solon-Biet, Melissa C Edwards, Ali Aflatounian, Robert B Gilchrist, Stephen J Simpson, David J Handelsman, Nadeem O Kaakoush, Kirsty A Walters
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial
Externí odkaz:
https://doaj.org/article/b8726557763444eca5d070104fa8422e
Autor:
David Raubenheimer, Alistair M. Senior, Christen Mirth, Zhenwei Cui, Rong Hou, David G. Le Couteur, Samantha M. Solon-Biet, Pierre Léopold, Stephen J. Simpson
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104315- (2022)
Summary: Animals require specific blends of nutrients that vary across the life course and with circumstances, e.g., health and activity levels. Underpinning and complicating these requirements is that individual traits may be optimized on different
Externí odkaz:
https://doaj.org/article/f5fbf4cca80842698fc139a0e17d58a3
Autor:
Xiangnan Xu, Samantha M. Solon-Biet, Alistair Senior, David Raubenheimer, Stephen J. Simpson, Luigi Fontana, Samuel Mueller, Jean Y. H. Yang
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Nutrigenomics aims at understanding the interaction between nutrition and gene information. Due to the complex interactions of nutrients and genes, their relationship exhibits non-linearity. One of the most effective and efficient
Externí odkaz:
https://doaj.org/article/1ff1f12d323c42f694cdcb119c85bb70
Autor:
Valentina Rodriguez Paris, Samantha M. Solon-Biet, Alistair M. Senior, Melissa C. Edwards, Reena Desai, Nicodemus Tedla, Madeleine J. Cox, William L. Ledger, Robert B. Gilchrist, Stephen J. Simpson, David J. Handelsman, Kirsty A. Walters
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Lifestyle interventions are first-line treatment for women with polycystic ovary syndrome (PCOS), but the optimal diet remains undefined. Here the authors identify an optimum dietary macronutrient balance that can rectify PCOS reproductive traits in
Externí odkaz:
https://doaj.org/article/3a5629219905422c9f942f689f72059f
Autor:
Yann W. Yap, Patricia M. Rusu, Andrea Y. Chan, Barbara C. Fam, Andreas Jungmann, Samantha M. Solon-Biet, Christopher K. Barlow, Darren J. Creek, Cheng Huang, Ralf B. Schittenhelm, Bruce Morgan, Dieter Schmoll, Bente Kiens, Matthew D. W. Piper, Mathias Heikenwälder, Stephen J. Simpson, Stefan Bröer, Sofianos Andrikopoulos, Oliver J. Müller, Adam J. Rose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Dietary protein dilution, where protein is reduced and replaced by other nutrient sources without caloric restriction, promotes metabolic health via the hepatokine Fgf21. Here, the authors show that essential amino acids threonine and tryptophan are
Externí odkaz:
https://doaj.org/article/36856bb21e41464a998b62244a235694
Autor:
Amelia K. Fotheringham, Samantha M. Solon-Biet, Helle Bielefeldt-Ohmann, Domenica A. McCarthy, Aisling C. McMahon, Kari Ruohonen, Isaac Li, Mitchell A. Sullivan, Rani O. Whiddett, Danielle J. Borg, Victoria C. Cogger, William O. Ballard, Nigel Turner, Richard G. Melvin, David Raubenheimer, David G. Le Couteur, Stephen J. Simpson, Josephine M. Forbes
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103308- (2021)
Summary: The kidneys balance many byproducts of the metabolism of dietary components. Previous studies examining dietary effects on kidney health are generally of short duration and manipulate a single macronutrient. Here, kidney function and structu
Externí odkaz:
https://doaj.org/article/379150e318a640cc9c9a9ea0ac822fba
Autor:
Devin Wahl, Samantha M. Solon-Biet, Victoria C. Cogger, Luigi Fontana, Stephen J. Simpson, David G. Le Couteur, Rosilene V. Ribeiro
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104481- (2019)
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders, and neurodegenerative disease. There is emerging evidence that interventions that improve metabolic health with aging may also be effective for brain heal
Externí odkaz:
https://doaj.org/article/6bf0f2e42e554968bf2b530decc0a09b
Autor:
Cristal M. Hill, Thomas Laeger, Madeleine Dehner, Diana C. Albarado, Blaise Clarke, Desiree Wanders, Susan J. Burke, J. Jason Collier, Emily Qualls-Creekmore, Samantha M. Solon-Biet, Stephen J. Simpson, Hans-Rudolf Berthoud, Heike Münzberg, Christopher D. Morrison
Publikováno v:
Cell Reports, Vol 27, Iss 10, Pp 2934-2947.e3 (2019)
Summary: Reduced dietary protein intake induces adaptive physiological changes in macronutrient preference, energy expenditure, growth, and glucose homeostasis. We demonstrate that deletion of the FGF21 co-receptor βKlotho (Klb) from the brain produ
Externí odkaz:
https://doaj.org/article/fbc23e92f7fb44a2b7e2fd673a5fd932