Zobrazeno 1 - 10
of 650
pro vyhledávání: '"M, Snell"'
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103356- (2024)
Summary: The snapshot nature of single-cell transcriptomics presents a challenge for studying the dynamics of gene expression. Metabolic labeling, where nascent RNA is labeled with 4-thiouridine (4sU), captures temporal information at the single-cell
Externí odkaz:
https://doaj.org/article/dc5893fd65394c9fbb1cbf68a3f339f6
Autor:
Jeffrey M. Rybak, Jinhong Xie, Adela Martin-Vicente, Xabier Guruceaga, Harrison I. Thorn, Ashley V. Nywening, Wenbo Ge, Ana C. O. Souza, Amol C. Shetty, Carrie McCracken, Vincent M. Bruno, Josie E. Parker, Steven L. Kelly, Hannah M. Snell, Christina A. Cuomo, P. David Rogers, Jarrod R. Fortwendel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Triazole antifungals function as ergosterol biosynthesis inhibitors and are frontline therapy for invasive fungal infections, such as invasive aspergillosis. The primary mechanism of action of triazoles is through the specific inhibition of
Externí odkaz:
https://doaj.org/article/f05294528fb640d8a22b184dae7ef4b2
Autor:
Aryamav Pattnaik, Adeeba H. Dhalech, Stephanie A. Condotta, Caleb Corn, Martin J. Richer, Laura M. Snell, Christopher M. Robinson
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundBiological sex plays an integral role in the immune response to various pathogens. The underlying basis for these sex differences is still not well defined. Here, we show that Coxsackievirus B3 (CVB3) induces a viral-specific CD4+ T cell re
Externí odkaz:
https://doaj.org/article/e66c6ee82112422b86e1833c06e90ad2
Autor:
Mengdi Guo, Diala Abd-Rabbo, Bruna C. Bertol, Madeleine Carew, Sabelo Lukhele, Laura M. Snell, Wenxi Xu, Giselle M. Boukhaled, Heidi Elsaesser, Marie Jo Halaby, Naoto Hirano, Tracy L. McGaha, David G. Brooks
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113047- (2023)
Summary: CD4 T cells are central effectors of anti-cancer immunity and immunotherapy, yet the regulation of CD4 tumor-specific T (TTS) cells is unclear. We demonstrate that CD4 TTS cells are quickly primed and begin to divide following tumor initiati
Externí odkaz:
https://doaj.org/article/e4149f45150d4ef1af757d28b5084332
Autor:
Keith D. M. Snell
Pioneering and interdisciplinary in nature, this bibliography constitutes a comprehensive list of regional fiction for every county of Ireland, Scotland, Wales and England over the past two centuries. In addition, other regions of a usually topograph
Autor:
Charlotte Douglas, Valdone Maciulyte, Jasmin Zohren, Daniel M. Snell, Shantha K. Mahadevaiah, Obah A. Ojarikre, Peter J. I. Ellis, James M. A. Turner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
In areas such as animal research and agriculture a single sex is often required in abundance, leading to wasted resources and ethical considerations. Here the authors develop a CRISPR/Cas9 mediated synthetic lethal system that enables the production
Externí odkaz:
https://doaj.org/article/212d0ada3e1b4efc91787d0acfd6cf85
Autor:
K. D. M. Snell
What role did the parish play in people's lives in England and Wales between 1700 and the mid-twentieth century? By comparison with globalisation and its dislocating effects, the book stresses how important parochial belonging once was. Professor Sne
Autor:
Laura M. Snell, Ivan Osokine, Douglas H. Yamada, Justin Rafael De la Fuente, Heidi J. Elsaesser, David G. Brooks
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3286-3296 (2016)
Viral persistence specifically inhibits CD4 Th1 responses and promotes Tfh immunity, but the mechanisms that suppress Th1 cells and the disease consequences of their loss are unclear. Here, we demonstrate that the loss of CD4 Th1 cells specifically l
Externí odkaz:
https://doaj.org/article/38afc539859f41e0a03d88bba858a20b
Autor:
Mengdi Guo, Diala Abd-Rabbo, Bruna Bertol, Madeleine Carew, Sabelo Lukhele, Laura M Snell, Wenxi Xu, Giselle M Boukhaled, Heidi Elsaesser, Marie jo Halaby, Naoto Hirano, Tracy L McGaha, David G Brooks
Publikováno v:
bioRxiv
CD4 T cells are important effectors of anti-tumor immunity, yet the regulation of CD4 tumor-specific T (TTS) cells during cancer development is still unclear. We demonstrate that CD4 TTScells are initially primed in the tumor draining lymph node and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc68d8039b703b05f19324e33bbb107
https://europepmc.org/articles/PMC10153152/
https://europepmc.org/articles/PMC10153152/
Autor:
K. D. M. Snell
Publikováno v:
Family & Community History. 25:3-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::935f199d76cab2fbdc3db67c6195605d
https://doi.org/10.1080/14631180.2022.2095734
https://doi.org/10.1080/14631180.2022.2095734