Zobrazeno 1 - 10
of 1 035
pro vyhledávání: '"M, Sherwood"'
Autor:
Nathan P. Ward, Sang Jun Yoon, Tyce Flynn, Amanda M. Sherwood, Maddison A. Olley, Juliana Madej, Gina M. DeNicola
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cysteine metabolism occurs across cellular compartments to support diverse biological functions and prevent the induction of ferroptosis. Though the disruption of cytosolic cysteine metabolism is implicated in this form of cell death, it is
Externí odkaz:
https://doaj.org/article/3f823335e6504dec9918dcb917a1e452
Autor:
Jason Wallach, Andrew B. Cao, Maggie M. Calkins, Andrew J. Heim, Janelle K. Lanham, Emma M. Bonniwell, Joseph J. Hennessey, Hailey A. Bock, Emilie I. Anderson, Alexander M. Sherwood, Hamilton Morris, Robbin de Klein, Adam K. Klein, Bruna Cuccurazzu, James Gamrat, Tilka Fannana, Randy Zauhar, Adam L. Halberstadt, John D. McCorvy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5-HT2A-Gq/11 and β-arrestin2 transducers, making their respectiv
Externí odkaz:
https://doaj.org/article/30bf5d9d5f33452682a561177a856eb2
Publikováno v:
ACS Omega, Vol 7, Iss 6, Pp 5429-5436 (2022)
Externí odkaz:
https://doaj.org/article/d22db13ce643462d9119d37ae3664e9f
Autor:
Paul S. Cassidy, Ruth A. Kelly, Ester Reina-Torres, Joseph M. Sherwood, Marian M. Humphries, Anna-Sophia Kiang, G. Jane Farrar, Colm O’Brien, Matthew Campbell, W. Daniel Stamer, Darryl R. Overby, Pete Humphries, Jeffrey O’Callaghan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 86-94 (2021)
Systemic or localized application of glucocorticoids (GCs) can lead to iatrogenic ocular hypertension, which is a leading cause of secondary open-angle glaucoma and visual impairment. Previous work has shown that dexamethasone increases zonula occlud
Externí odkaz:
https://doaj.org/article/d2e3a1e4567a46bd80bb688a8be4ad9b
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 32067-32075 (2020)
Externí odkaz:
https://doaj.org/article/0f8c554083fd4d65843970a27b753c02
Autor:
Nathaniel D. Chu, Haixin Sarah Bi, Ryan O. Emerson, Anna M. Sherwood, Michael E. Birnbaum, Harlan S. Robins, Eric J. Alm
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells
Externí odkaz:
https://doaj.org/article/ce0c5f9640c74c6d895963351a66b37d
Autor:
Steven W Cotten, Frederick G Strathmann, Frederick S Barrett, Laura Labay, James Mullally, Alexander M Sherwood, Frank Wiegand
Publikováno v:
Clinical Chemistry. 69:319-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5013d578c65d39d422c19fb3918a9888
https://doi.org/10.1093/clinchem/hvad016
https://doi.org/10.1093/clinchem/hvad016
Autor:
Elizabeth M. Boazak, Rebecca King, Jiaxing Wang, Cassandra M. Chu, Aaron M. Toporek, Joseph M. Sherwood, Darryl R. Overby, Eldon E. Geisert, C. Ross Ethier
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The biomechanical properties of the cornea and sclera are important in the onset and progression of multiple ocular pathologies and vary substantially between individuals, yet the source of this variation remains unknown. Here we identify genes putat
Externí odkaz:
https://doaj.org/article/bb3af9c3e014470e9df9a0ee7ec893e7
Autor:
Wei Zhu, Fei Hou, Jingwang Fang, Mohammad Reza Bahrani Fard, Yani Liu, Shouyan Ren, Shen Wu, Yunkun Qi, Shangru Sui, A. Thomas Read, Joseph M. Sherwood, Wei Zou, Hongxia Yu, Jingxue Zhang, Darryl R. Overby, Ningli Wang, C. Ross Ethier, KeWei Wang
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102042- (2021)
Summary: Controlling intraocular pressure (IOP) remains the mainstay of glaucoma therapy. The trabecular meshwork (TM), the key tissue responsible for aqueous humor (AH) outflow and IOP maintenance, is very sensitive to mechanical forces. However, it
Externí odkaz:
https://doaj.org/article/c3fe1e00e07f42fbb931ae6b20207de7
Autor:
Roberta E. Emetu PhD, MPH, MLS, William L. Yarber HSD, Catherine M. Sherwood-Laughlin HSD, MPH, MA, Alexis S. Brandt MPH
Publikováno v:
American Journal of Men's Health, Vol 14 (2020)
Young men who have sex with men (YMSM) have the highest burden of sexually transmitted infections (STIs), including HIV. Childhood sexual abuse (CSA) is a risk factor for high-risk sexual behavior and STI acquisition. Studies that have explored sexua
Externí odkaz:
https://doaj.org/article/3db29423cec04d968f75a67361047d07