Zobrazeno 1 - 10
of 209
pro vyhledávání: '"M, Selaru"'
Autor:
Huimin Yu, Zixin Zhang, Gangping Li, Yan Feng, Lingling Xian, Fatemeh Bakhsh, Dongqing Xu, Cheng Xu, Tyrus Vong, Bin Wu, Florin M. Selaru, Fengyi Wan, Mark Donowitz, G. William Wong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 4, Pp 1000-1015 (2023)
Background & Aims: The adipokine CTRP3 has anti-inflammatory effects in several nonintestinal disorders. Although serum CTRP3 is reduced in patients with inflammatory bowel disease (IBD), its function in IBD has not been established. Here, we elucida
Externí odkaz:
https://doaj.org/article/387ac2fa670e4b77a63d9130180641ca
Publikováno v:
iScience, Vol 26, Iss 3, Pp 106095- (2023)
Summary: Cholangiocarcinoma (CCA) is a biliary tree malignancy with a dismal prognosis. Tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) has been shown to be involved in drug resistance. To model the interactions between c
Externí odkaz:
https://doaj.org/article/86e6377c74bc44b08f9942d9adede807
Publikováno v:
Medicina, Vol 59, Iss 9, p 1599 (2023)
Extracellular vesicles (EVs) play critical roles in intercellular communication by transporting bioactive cargo to recipient cells. EVs have been implicated in a range of physiological and pathological processes, including tumor progression, metastas
Externí odkaz:
https://doaj.org/article/214f5a8029ee4f0286bbbb806cb43720
Autor:
Evangelos Tsipotis, Ankith Maremanda, Laura Bowles Zeiser, Caoilfhionn Connolly, Sowmya Sharma, Sharon Dudley-Brown, Sarah Frey, Mark Lazarev, Joanna M. Melia, Alyssa M. Parian, Dorry L. Segev, Brindusa Truta, Huimin Yu, William A. Werbel, Florin M. Selaru
Publikováno v:
Medicina, Vol 59, Iss 8, p 1487 (2023)
Background: The emergence of new SARS-CoV-2 variants calls for more data on SARS-CoV-2 mRNA vaccine response. Aims: We aimed to assess the response to a third mRNA vaccine dose against SARS-CoV-2 in inflammatory bowel disease (IBD) patients. Methods:
Externí odkaz:
https://doaj.org/article/846236f07bab4217ac3e6fb73de14198
Autor:
Ling Li, Mohamad I. Itani, Kevan J. Salimian, Yue Li, Olaya Brewer Gutierrez, Haijie Hu, George Fayad, Jean A. Donet, Min Kyung Joo, Laura M. Ensign, Vivek Kumbhari, Florin M. Selaru
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Gastrointestinal (GI) strictures are difficult to treat in a variety of disease processes. Currently, there are no Food and Drug Administration (FDA) approved drugs for fibrosis in the GI tract. One of the limitations to developing anti-fibr
Externí odkaz:
https://doaj.org/article/0036aedcaedd4c609bd0bb02b3498583
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Patients with ulcerative colitis are typically suspected of an inflammatory flare based on suggestive symptoms of inflammation. The aim of this study was to evaluate the impact of inflammation on colonic motility and rectal sensitivity from
Externí odkaz:
https://doaj.org/article/bd1bd660241f45fba680504e583ecb1a
Autor:
Ling Li, Gilad Halpert, Michael G. Lerner, Haijie Hu, Peter Dimitrion, Matthew J. Weiss, Jin He, Benjamin Philosophe, Richard Burkhart, William R. Burns, Russell N. Wesson, Andrew MacGregor Cameron, Christopher L. Wolfgang, Christos Georgiades, Satomi Kawamoto, Nilofer S. Azad, Mark Yarchoan, Stephen J. Meltzer, Kiyoko Oshima, Laura M. Ensign, Joel S. Bader, Florin M. Selaru
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
Hepatocellular carcinoma (HCC) is the sixth most common and the fourth most deadly cancer worldwide. The development cost of new therapeutics is a major limitation in patient outcomes. Importantly, there is a paucity of preclinical HCC models in whic
Externí odkaz:
https://doaj.org/article/f683fedaae0d4fbb8bdd07f74ee54fb0
Autor:
Yuting Huang, Robert L Kruse, Hui Ding, Mohamad I Itani, Jonathan Morrison, Zack Z Wang, Florin M Selaru, Vivek Kumbhari
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249931 (2021)
The biliary system is routinely accessed for clinical purposes via endoscopic retrograde cholangiopancreatography (ERCP). We previously pioneered ERCP-mediated hydrodynamic injection in large animal models as an innovative gene delivery approach for
Externí odkaz:
https://doaj.org/article/2734c5a2179a4748969f80ee7202160d
Autor:
Ling Li, Yicheng Zhang, Yang Zhou, Haijie Hu, Yizong Hu, Christos Georgiades, Hai‐Quan Mao, Florin M. Selaru
Publikováno v:
Hepatology. 76:1660-1672
Hepatocellular carcinoma (HCC) represents the third leading cause of cancer-related mortality in the world. Over the past two decades, there has been minimal improvement in therapies as well as clinical outcomes for patients with Barcelona Clinic Liv
Autor:
Hannah J Vaughan, Camila G Zamboni, Kathryn M Luly, Ling Li, Kathleen L Gabrielson, Laboni F Hassan, Nicholas P Radant, Pranshu Bhardwaj, Florin M Selaru, Martin G Pomper, Jordan J Green
Publikováno v:
International Journal of Nanomedicine.
Hannah J Vaughan,1,2 Camila G Zamboni,1,2 Kathryn M Luly,1,2 Ling Li,3 Kathleen L Gabrielson,4 Laboni F Hassan,1,2 Nicholas P Radant,1,2 Pranshu Bhardwaj,1,2 Florin M Selaru,3 Martin G Pomper,1,5,6 Jordan J Green1,2,6,7 1Department of Biomedical Engi