Zobrazeno 1 - 10
of 376
pro vyhledávání: '"M, Schutten"'
Autor:
Gail D. Lewis, Guangmin Li, Jun Guo, Shang-Fan Yu, Carter T. Fields, Genee Lee, Donglu Zhang, Peter S. Dragovich, Thomas Pillow, BinQing Wei, Jack Sadowsky, Douglas Leipold, Tim Wilson, Amrita Kamath, Michael Mamounas, M. Violet Lee, Ola Saad, Voleak Choeurng, Alexander Ungewickell, Sharareh Monemi, Lisa Crocker, Kevin Kalinsky, Shanu Modi, Kyung Hae Jung, Erika Hamilton, Patricia LoRusso, Ian Krop, Melissa M. Schutten, Renee Commerford, Mark X. Sliwkowski, Eunpi Cho
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan. To develop a differentiated HER2 ADC, we chose an antibody that does not compete with trastuzumab or pertuzuma
Externí odkaz:
https://doaj.org/article/654b41b090ea4a87be21fb42ec554dae
Autor:
Kahren van Eer, Ihsane Laâbi, Birgit H.B. van Benthem, Renske D.M. Steenbergen, Audrey J. King, D. Adema, R. Buist-Arkema, A. Beerens, D. Luijt, S. Meijer, J. Schirm, M. Peeters, J. Rossen, H. Verbakel, P. van Esch, J. Verweij, A. van der Eijk, R. Huisman, C. Kerkhof, H. Korff, M. Schutten, J. Velzing, F. Verduyn-Lunel, S. Lakbiach, P. van Rosmalen, R. Schuurman, E. Doorn, L. Masthoff, E. Pannekoek, V. Sigurdsson, D. Abma, K. Adams, S. Bruisten, I. Linde, P. Oostvogel, C. Touwen, W. Vermeulen, A. Brink, J. Nelissen, P. Wolffs, N. Duijvendijk, P. Schneeberger, M. Dinnissen van Poppel, W. Melchers, Y. Poort, M.Hooghiemstra Izore, H. Huisman, J. Weel, F. Bosma, F. Geeraedts, I. Polman, P.van Goor Isala, M. Wolfhagen, C. de Mooij, E. van Koolwijk, M. Peters, C. Swanink, R. Tiemessen, T. van Zwet, J. Janssen, M. Pelsers, W. de Waal, G. Aalfs, J. Kiewiet, P. Sanders, H. van Buel- Bruins, C. van Bokhoven-Rombouts, P. Cornelissen, M. Kersten, C. van Ruitenbeek, I. Molenaar, M. Bugter, H. Götz, M. Illidge-Onder de Linden, M. Mattijssen, J. Stam, E. Swaders, F. de Groot, F. Postma, E. Brouwers, A. Niekamp, M. Smit, A. Botraby, D. Bukasa, C. de Haan, P. Hut-van Vliet, T. Taconis, M. de Graas, I. Hondelink, C. Kampman, A. Gelissen-Hansen, I. de Koning, H. van Kruchten, M. van de Pas, H. Fennema, T. Heijman, A. Hogewoning, A. van Leeuwen, M. van Rooijen, F. Neienhuijsen, M. Pelgrim
Publikováno v:
Tumour Virus Research, Vol 13, Iss , Pp 200233- (2022)
Concurrent genital-anal human papillomavirus (HPV) infections may impose an increased anal cancer risk in women with HPV-related genital lesions. High viral load may facilitate genital-anal HPV concurrence. Genital and anal HPV is reduced by a bivale
Externí odkaz:
https://doaj.org/article/546b16f9cbd94c19aa58c2b7f562555e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The Hippo pathway is a critical regulator of cell and organ growth and has emerged as a target for therapeutic intervention in cancers. Its signaling is thought to play an important role in various physiological processes including homeostasis and ti
Externí odkaz:
https://doaj.org/article/467c6ad6489b461b93d41ecfda300183
Autor:
Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta
Figure S1. Validation of anti-GFRA1 antibodies (R&D systems and GNE-8H6) for the use of Immunohistochemistry (IHC) analysis; Figure S2. ELISA analyses to test binding specificity of anti-GFRA1 antibodies to GFRA1 (A) and GFRA2 (B) extra cellular doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100a6557ca8c0f2a229a1ced8e41d71e
https://doi.org/10.1158/1535-7163.22505118
https://doi.org/10.1158/1535-7163.22505118
Nicotine replacement therapy is often used to maintain smoking cessation. However, concerns exist about the safety of long-term nicotine replacement therapy use in ex-smokers and its concurrent use in smokers. In this study, we determined the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d077e894dee27aac70d563d3143563fe
https://doi.org/10.1158/1940-6207.c.6544277
https://doi.org/10.1158/1940-6207.c.6544277
Autor:
Andrew G. Polson, Peter S. Dragovich, Jack D. Sadowsky, Thomas Pillow, Melissa M. Schutten, Rebecca K. Rowntree, Peter Yan, Kyu Hong, Montserrat Carrasco-Triguero, Fiona Zhong, Helen Booler, Douglas Leipold, Geoffrey del Rosario, Bing Zheng, Donna W. Lee, Shang-Fan Yu
We are interested in developing a second generation of antibody–drug conjugates (ADCs) for the treatment of non-Hodgkin lymphoma (NHL) that could provide a longer duration of response and be more effective in indolent NHL than the microtubule-inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e0b06cd0c060e113446fb4818a68f5
https://doi.org/10.1158/1535-7163.c.6542727.v1
https://doi.org/10.1158/1535-7163.c.6542727.v1
Autor:
Andrew G. Polson, Peter S. Dragovich, Jack D. Sadowsky, Thomas Pillow, Melissa M. Schutten, Rebecca K. Rowntree, Peter Yan, Kyu Hong, Montserrat Carrasco-Triguero, Fiona Zhong, Helen Booler, Douglas Leipold, Geoffrey del Rosario, Bing Zheng, Donna W. Lee, Shang-Fan Yu
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6caa4c5b88f15663e735cef0c387c4
https://doi.org/10.1158/1535-7163.22520694
https://doi.org/10.1158/1535-7163.22520694
Autor:
Jagath R. Junutula, Paul Polakis, Richard H. Scheller, Mark S. Dennis, Deepak Sampath, Jo-Anne Hongo, Helga Raab, Katherine R. Kozak, Aimee Fourie-O'Donohue, Ron Firestein, Robert Piskol, Eric Cheng, Mary Ann T. Go, Kirsten A. Poon, Fiona Zhong, Rachana Ohri, Coenraad Kuijl, Dongwei Li, Melissa M. Schutten, Meredith Hazen, Yvonne Chen, Lisa M. Crocker, Sunil Bhakta
Luminal A (hormone receptor-positive) breast cancer constitutes 70% of total breast cancer patients. In an attempt to develop a targeted therapeutic for this cancer indication, we have identified and characterized Glial cell line–Derived Neurotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ebbf88322d045b6d0c4b08c2c22021d
https://doi.org/10.1158/1535-7163.c.6537960.v1
https://doi.org/10.1158/1535-7163.c.6537960.v1
Autor:
Thomas H. Pillow, Andrew G. Polson, Peter S. Dragovich, Hans K. Erickson, Pragya Adhikari, John Wai, Zijin Xu, Jinhua Chen, Katherine R. Kozak, Josefa dela Cruz-Chuh, Keyang Xu, Carl Ng, Amrita V. Kamath, Douglas D. Leipold, Shang-Fan Yu, Mary Ann T. Go, Geoffrey del Rosario, Fiona Zhong, Melissa M. Schutten, Chris Frantz, Breanna S. Vollmar
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5429ac6c382f94a2b29d630d8d1ebd26
https://doi.org/10.1158/1535-7163.22522233
https://doi.org/10.1158/1535-7163.22522233
Perspectives on This Article from Chronic Nicotine Consumption Does Not Influence 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone–Induced Lung Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc7fcc7976dc15558627c4f64a734c8
https://doi.org/10.1158/1940-6207.22524494.v1
https://doi.org/10.1158/1940-6207.22524494.v1