Zobrazeno 1 - 10
of 67
pro vyhledávání: '"M, Schleimer"'
Publikováno v:
Clinical and Experimental Dermatology. 36:18-23
Summary Background. Previous studies have shown that concomitant administration of food may enhance the bioavailability of oral retinoids. Aim. To assess the influence of food on the pharmacokinetics (PK) of alitretinoin after a single oral dose. Met
Autor:
I Meyer, B. Roos, J. Maares, J. Sauer, T. Brown, M. Schleimer, A. H. Schmitt-Hoffmann, E. Weidekamm
Publikováno v:
Clinical and Experimental Dermatology. 36:12-17
Summary Background. Alitretinoin, like all retinoids, is teratogenic, and can only be given to women of childbearing potential if pregnancy is excluded and a strict contraceptive programme is followed. Aim. This study was designed to determine whethe
Autor:
P. T. Leese, J. Sauer, M. Schleimer, J. Maares, E. Weidekamm, B. Roos, A. H. Schmitt-Hoffmann, A. Schoetzau
Publikováno v:
Clinical and Experimental Dermatology. 36:4-11
BACKGROUND: Alitretinoin (9-cis retinoic acid) is currently registered in many European countries and in Canada as the only licensed treatment for severe chronic hand eczema unresponsive to potent topical corticosteroids. Alitretinoin like all retino
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:1105-1111
BAL5788 is a water-soluble prodrug of BAL9141, a new broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- and vancomycin-resistant staphylococci and penicillin-resistant streptococci. In plasma BAL5788 is rapidly co
Publikováno v:
Tetrahedron: Asymmetry. 8:327-335
Only one of the four enantiomers of 5-fluoromethylornithine 1 was an irreversible inhibitor of ornithine aminotransferase. The active enantiomer 1a was synthesized from diaminoadipic acid 2 with a chemical diastereomeric separation and an enantiomeri
Autor:
A H, Schmitt-Hoffmann, B, Roos, J, Sauer, T, Brown, E, Weidekamm, I, Meyer, M, Schleimer, J, Maares
Publikováno v:
Clinical and experimental dermatology. 36
Alitretinoin, like all retinoids, is teratogenic, and can only be given to women of childbearing potential if pregnancy is excluded and a strict contraceptive programme is followed.This study was designed to determine whether alitretinoin in the seme
Publikováno v:
Clinical and experimental dermatology. 36
Previous studies have shown that concomitant administration of food may enhance the bioavailability of oral retinoids.To assess the influence of food on the pharmacokinetics (PK) of alitretinoin after a single oral dose.This was a single-dose, open-l
Autor:
A H, Schmitt-Hoffmann, B, Roos, J, Sauer, M, Schleimer, A, Schoetzau, P T, Leese, E, Weidekamm, J, Maares
Publikováno v:
Clinical and experimental dermatology. 36
Alitretinoin (9-cis retinoic acid) is currently registered in many European countries and in Canada as the only licensed treatment for severe chronic hand eczema unresponsive to potent topical corticosteroids. Alitretinoin, like all retinoids, is ter
Publikováno v:
ChemInform. 28
Only one of the four enantiomers of 5-fluoromethylornithine 1 was an irreversible inhibitor of ornithine aminotransferase. The active enantiomer 1a was synthesized from diaminoadipic acid 2 with a chemical diastereomeric separation and an enantiomeri
Autor:
William H. Pirkle, Christopher J. Welch, J. Andrew Burke, Bo Lamm, Patrick Camilleri, Volker Schurig, M. Jung, S. Mayer, D. Schmalzing, M. Schleimer, Allan Taylor, Catherine A. Blackledge, Jeremy K. Nicholson, David A. R. Williams, Ian D. Wilson, Everardus J. Ariëns
Publikováno v:
Anal. Proc.. 29:225-234