Zobrazeno 1 - 10
of 1 565
pro vyhledávání: '"M, STANKOVIC"'
Autor:
Hinnerk Schulz-Hildebrandt, Svetolik Spasic, Fang Hou, Kuan-Chung Ting, Shelley Batts, Guillermo Tearney, Konstantina M. Stankovic
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Sensorineural hearing loss (SNHL) is caused by damage to the mechanosensory hair cells and auditory neurons of the cochlea. The development of imaging tools that can directly visualize or provide functional information about a patient’s cochlear ce
Externí odkaz:
https://doaj.org/article/e60b5c6919524a3ca23c2e1c224b8af8
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1407 (2024)
The inner ear organs responsible for hearing (cochlea) and balance (vestibular system) are susceptible to oxidative stress due to the high metabolic demands of their sensorineural cells. Oxidative stress-induced damage to these cells can cause hearin
Externí odkaz:
https://doaj.org/article/df02e61c57754f34a909e7947e377d71
Autor:
Alfred T. Harding, Karen Ocwieja, Minjin Jeong, Yichen Zhang, Valerie Leger, Nairuti Jhala, Konstantina M. Stankovic, Lee Gehrke
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTCongenital hearing loss is a common chronic condition affecting children in both developed and developing nations. Viruses correlated with congenital hearing loss include human cytomegalovirus (HCMV) and Zika virus (ZIKV), which causes congen
Externí odkaz:
https://doaj.org/article/d952475ee8e2487e8275ecf2a527d2d4
Publikováno v:
The Lancet Regional Health. Americas, Vol 29, Iss , Pp 100659- (2024)
Summary: Background: Tinnitus is a potentially disabling condition with few treatments. We examined the prevalence and characteristics of tinnitus among demographic groups in the United States (US) and assessed associated factors and tinnitus-related
Externí odkaz:
https://doaj.org/article/d53bd1d4909c4b2283e0cb63cb96745e
Autor:
Varun Sagi, Nikitha Kosaraju, Lindsay S. Moore, Jip Y. Mulders, Mehmet Solyali, Xiaojie Ma, Donald P. Regula, Jody E. Hooper, Konstantina M. Stankovic
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Human temporal bones (HTBs) are invaluable resources for the study of otologic disorders and for evaluating novel treatment approaches. Given the high costs and technical expertise required to collect and process HTBs, there has been a decline in the
Externí odkaz:
https://doaj.org/article/76b200e223d44c0a8bc82f3de89c7c52
Autor:
Takeshi Fujita, Richard Seist, Shyan-Yuan Kao, Vitor Soares, Lorena Panano, Radhika S. Khetani, Lukas D. Landegger, Shelley Batts, Konstantina M. Stankovic
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionVestibular schwannoma (VS) is an intracranial tumor that arises on the vestibular branch of cranial nerve VIII and typically presents with sensorineural hearing loss (SNHL). The mechanisms of this SNHL are postulated to involve alteration
Externí odkaz:
https://doaj.org/article/76cfd9b3cd9145bcb672c8c5f1451dce
Autor:
Joel T. Rämö, Tuomo Kiiskinen, Richard Seist, Kristi Krebs, Masahiro Kanai, Juha Karjalainen, Mitja Kurki, Eija Hämäläinen, Paavo Häppölä, Aki S. Havulinna, Heidi Hautakangas, FinnGen, Reedik Mägi, Priit Palta, Tõnu Esko, Andres Metspalu, Matti Pirinen, Konrad J. Karczewski, Samuli Ripatti, Lili Milani, Konstantina M. Stankovic, Antti Mäkitie, Mark J. Daly, Aarno Palotie
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Otosclerosis is a common form of hearing loss, with an unclear genetic etiology. Here, the authors perform a genome-wide association study meta-analysis of otosclerosis identifying 27 genetic loci, pointing to genes involved in bone remodeling, skele
Externí odkaz:
https://doaj.org/article/6c545f6161e84ab58fce429684406cdc
Autor:
Samuel Early, M. Ahsan Saad, Srivalleesha Mallidi, Amer Mansour, Richard Seist, Tayyaba Hasan, Konstantina M. Stankovic
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Cholesteatoma is a potentially serious complication of chronic ear infections and requires surgical intervention for definitive management. Long-term complications include a frequent need for repeat surgical intervention for disease recurren
Externí odkaz:
https://doaj.org/article/d33fcb6f2a3a4b29940274e4d3967439
Autor:
Eva Andres-Mateos, Lukas D. Landegger, Carmen Unzu, Jean Phillips, Brian M. Lin, Nicholas A. Dewyer, Julio Sanmiguel, Fotini Nicolaou, Michelle D. Valero, Kathrin I. Bourdeu, William F. Sewell, Rudolph J. Beiler, Michael J. McKenna, Konstantina M. Stankovic, Luk H. Vandenberghe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Gene therapy using Adeno-associated viral vectors (AAV) rescues hearing and balance deficits in mouse models of human disorders. Here, the authors show that AAVAnc80L65 allows efficient cochlear gene transfer in nonhuman primates, and motivate future
Externí odkaz:
https://doaj.org/article/7e6b7c587b2a4cc9b15c510a61c21f79
Autor:
Minjin Jeong, Karen E. Ocwieja, Dongjun Han, P. Ashley Wackym, Yichen Zhang, Alyssa Brown, Cynthia Moncada, Andrea Vambutas, Theodore Kanne, Rachel Crain, Noah Siegel, Valerie Leger, Felipe Santos, D. Bradley Welling, Lee Gehrke, Konstantina M. Stankovic
Publikováno v:
Communications Medicine, Vol 1, Iss 1, Pp 1-14 (2021)
Plain language summary Coronavirus disease 2019 (COVID-19) is an infectious disease caused by the novel coronavirus SARS-CoV-2. A growing number of sensory symptoms have been linked to this illness. Here, we describe patients with COVID-19 and new-on
Externí odkaz:
https://doaj.org/article/caaa18033e444b8284794201f082d3fe