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Baseline gut microbiome alpha diversity predicts chemotherapy-induced gastrointestinal symptoms in patients with breast cancer

Autor: Lauren D. Otto-Dobos, Lindsay D. Strehle, Brett R. Loman, Melina M. Seng, Sagar D. Sardesai, Nicole O. Williams, Margaret E. Gatti-Mays, Daniel G. Stover, Preeti K. Sudheendra, Robert Wesolowski, Rebecca R. Andridge, Michael T. Bailey, Leah M. Pyter

Publikováno v: npj Breast Cancer, Vol 10, Iss 1, Pp 1-12 (2024)

Abstract Chemotherapy frequently causes debilitating gastrointestinal symptoms, which are inadequately managed by current treatments. Recent research indicates the gut microbiome plays a role in the pathogenesis of these symptoms. The current study a

Externí odkaz: https://doaj.org/article/04e252979f9f4ccdb88f619c16922f89

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Akademický článek

Antibiotic treatment inhibits paclitaxel chemotherapy-induced activity deficits in female mice.

Autor: Corena V Grant, Kelley Jordan, Melina M Seng, Leah M Pyter

Publikováno v: PLoS ONE, Vol 18, Iss 5, p e0284365 (2023)

Chemotherapy, a mainstay in the treatment of cancer, is associated with severe and debilitating side effects. Side effects can be physical (e.g., gastrointestinal distress, anemia, and hair loss) or mental (e.g., fatigue, cognitive dysfunction). Chem

Externí odkaz: https://doaj.org/article/6aae541906f64e83b95fed0706129aa4

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Akademický článek

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Ultra-low NA step-index large mode area Yb-doped fiber with a germanium doped cladding for high power pulse amplification

Autor: Serene Huiting Lim, Song Liang Chua, Yongmin Jung, David J. Richardson, Huizi Li, Seongwoo Yoo, Chen Jian Chang, Y. M. Seng, K. J. Lim, Di Lin, Raghuraman Sidharthan

High concentration rare earth doped, large mode area (LMA) step-index fibers, which feature a very high cladding absorption per unit length at the pump wavelength, high efficiency, and excellent beam quality, are ideal for high power pulsed fiber las

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469111491b4e862afcc9fa0329fe7c50
https://eprints.soton.ac.uk/442348/

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A case for Tsai's Modulus, an invariant-based approach to stiffness

Publikováno v: Arteiro, A, Sharma, N, Melo, J D D, Ha, S K, Miravete, A, Miyano, Y, Massard, T, Shah, P D, Roy, S, Rainsberger, R, Rother, K, Cimini, C, Seng, J M, Arakaki, F K, Tay, T E, Lee, W I, Sihn, S, Springer, G S, Roy, A, Riccio, A, Di Caprio, F, Shrivastava, S, Nettles, A T, Catalanotti, G, Camanho, P P, Seneviratne, W, Marques, A T, Yang, H T & Hahn, H T 2020, ' A case for Tsai's Modulus, an invariant-based approach to stiffness ', Composite Structures, vol. 252, 112683 . https://doi.org/10.1016/j.compstruct.2020.112683

For the past six years, we have been benefiting from the discovery by Tsai and Melo (2014) that the trace of the plane stress stiffness matrix ( tr ( Q ) ) of an orthotropic composite is a fundamental and powerful scaling property of laminated compos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ecc8252d99e0c81205e8ac8f58f16c
http://hdl.handle.net/11591/436728

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Low NA Ge-Clad Step-Index Yb-Doped Fiber for High Power Picosecond Laser Pulses

Autor: Seongwoo Yoo, K. J. Lim, Serene Huiting Lim, Raghuraman Sidharthan, Y. M. Seng, Yongmin Jung, Dejiao Lin, Huizi Li, Song-Liang Chua, David J. Richardson, Chen Jian Chang

Publikováno v: 14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020).

We report short absorption length LMA Yb-doped fiber with a low NA (0.04) and the amplification of 190ps pulses to $101 \mu J$ pulse energy with 150W average power and $\gt 70$% slope efficiency using only 0.8 m of the fiber. © 2020 The Author(s)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00140d59ce5b2889ee3a4b137554108a
https://doi.org/10.1364/cleopr.2020.c5h_4

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Photodarkening Suppressed Low Loss Yb:Al:P Doped Fiber by All Solution Doping Technique

Autor: Chen Jian Chang, Y. M. Seng, Huizi Li, Seongwoo Yoo, Song-Liang Chua, Vmh Ng, K. J. Lim, K. Pita, Raghuraman Sidharthan

Publikováno v: 14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020).

We present an all solution doping technique to fabricate step index Yb-doped Aluminophosphosilicate fiber, with P2O5 powder used for incorporating Phosphorous. Low loss (8dB/Km), low NA (0.06) photodarkening suppressed step index fiber is reported.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ea0d4a296e8818e737bc339cf2b4b30
https://doi.org/10.1364/cleopr.2020.c6h_5

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Akademický článek

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Akademický článek

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Total Lymphatic Irradiation as Part of Conditioning in Pediatric Hematopoietic Stem Cell Transplantation: A Single Institution Experience From a Radiation Oncology Perspective

Autor: K. Vijayakumari, W.H. Leung, M. Seng, A. Ong, W.S. Looi, P.R. Iyer, Rajat Bhattacharyya, R.X. Wong, Ah Moy Tan, Mei Yoke Chan, T.N.A. Pham

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 111:e178

Purpose/Objective(s) Total lymphatic irradiation (TLI) is a procedure in which a patient's major lymph nodes and spleen are treated with low doses of radiation for recipient immunosuppression as part of multi-agent conditioning for cardiac, lung or h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b62f944c1c2cb62860256b5fd62c5ebb
https://doi.org/10.1016/j.ijrobp.2021.07.669

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