Zobrazeno 1 - 10
of 5 600
pro vyhledávání: '"M, Rubin"'
Autor:
Alison K. Barrett, Manisha R. Shingare, Andreas Rechtsteiner, Kelsie M. Rodriguez, Quynh N. Le, Tilini U. Wijeratne, Corbin E. Mitchell, Miles W. Membreno, Seth M. Rubin, Gerd A. Müller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Histone deacetylases (HDACs) play a crucial role in transcriptional regulation and are implicated in various diseases, including cancer. They are involved in histone tail deacetylation and canonically linked to transcriptional repression. Pr
Externí odkaz:
https://doaj.org/article/7a712aae55e44cccbb9dbbd6c0a5b6e1
Autor:
Laura C Cappelli, Bernice Kwong, Jarushka Naidoo, Jonathan Leventhal, Mario E Lacouture, Meghan J Mooradian, Douglas B Johnson, Justine Cohen, Aparna Hegde, Steven T Chen, Riley Fadden, Leyre Zubiri, Shawn Kwatra, Ryan J Sullivan, Kerry L Reynolds, Allison Betof Warner, Yevgeniy R Semenov, Nicole R LeBoeuf, Krista M Rubin, Anna K Dewan, Alina Markova, Allireza Alloo, Daniel Q Bach, Amina Bougrine, Leeann Burton, Mariana Castells, Lauren Guggina, Victor Huang, Benjamin Kaffenberger, Daniela Kroshinsky, Cecilia Larocca, Jon McDunn, Jennifer Choi, Vinod Nambudiri, Caroline A Nelson, Anisha B Patel, Julia Pimkina, Johnathan Rine, Maxwell Sauder, Sheila Shaigany, Afreen Shariff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
With an increasing number of patients eligible for immune checkpoint inhibitors, the incidence of immune-related adverse events (irAEs) is on the rise. Dermatologic immune-related adverse events (D-irAEs) are the most common and earliest to manifest,
Externí odkaz:
https://doaj.org/article/0f9ad47d419c4ad4b3131ec90c49be9f
Publikováno v:
Zeitschrift für Medizinische Physik, Vol 33, Iss 3, Pp 309-323 (2023)
The field of super-resolution ultrasound microvascular imaging has been rapidly growing over the past decade. By leveraging contrast microbubbles as point targets for localization and tracking, super-resolution ultrasound pinpoints the location of mi
Externí odkaz:
https://doaj.org/article/950c354182144191a21c04e4642e864a
Autor:
Gerald M Rubin, Yoshinori Aso
Publikováno v:
eLife, Vol 12 (2024)
How memories of past events influence behavior is a key question in neuroscience. The major associative learning center in Drosophila, the mushroom body (MB), communicates to the rest of the brain through mushroom body output neurons (MBONs). While 2
Externí odkaz:
https://doaj.org/article/6f7be72cd7154c64b4779663fd1b0468
Autor:
Omid Hamid, Diwakar Davar, Keisuke Shirai, Benjamin Izar, Charlotte E Ariyan, Michael K Wong, Jason J Luke, Janis M Taube, Anna C Pavlick, Meghan J Mooradian, Douglas B Johnson, Hussein A Tawbi, Tara C Mitchell, Ryan J Sullivan, April KS Salama, Krista M Rubin, Elizabeth I Buchbinder, Sarah A Weiss, Tina J Hieken, Geoffrey T Gibney, Rajan P Kulkarni, J Keith Tolley, Caressa Valdueza
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Since the first approval for immune checkpoint inhibitors (ICIs) for the treatment of cutaneous melanoma more than a decade ago, immunotherapy has completely transformed the treatment landscape of this chemotherapy-resistant disease. Combination regi
Externí odkaz:
https://doaj.org/article/f4721e0504094c6083b6710589696855
Autor:
Joseph R. Ortenero, Cluadine D. Doma, Ron Joshua M. Rubin, Katherine Cecile Kristie Vida R. Reyes, Vergel C. Bungay
Publikováno v:
Chemical Engineering Transactions, Vol 103 (2023)
The utilization of energy continues to increase every year due to urbanization, population growth, and industrial activity. Conventional thermal power plants that operate on fossil fuels supply not less than 80 % of the world’s primary energy. To l
Externí odkaz:
https://doaj.org/article/e4a31f4006ab4b3bb89a17397f5689ab
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
A new analysis of Rosetta mass spectra reveals an ensemble of complex organic molecules with striking similarities to other organic reservoirs in the Solar System, including Saturn’s ring rain material, pointing at a likely joint prestellar history
Externí odkaz:
https://doaj.org/article/f1cebc736f4642bc84c5702bcfd77067
Publikováno v:
Biogeosciences, Vol 19, Pp 2313-2331 (2022)
Anaerobic oxidation of methane (AOM) is among the main processes limiting the release of the greenhouse gas methane from natural environments. Geochemical profiles and experiments with fresh sediments from Lake Kinneret (Israel) indicate that iron-co
Externí odkaz:
https://doaj.org/article/1e96484e752c49aaaa9a905fb31d972b
Autor:
N. Belkin, T. Guy-Haim, M. Rubin-Blum, A. Lazar, G. Sisma-Ventura, R. Kiko, A. R. Morov, T. Ozer, I. Gertman, B. Herut, E. Rahav
Publikováno v:
Ocean Science, Vol 18, Pp 693-715 (2022)
Planktonic food webs were studied contemporaneously in a mesoscale cyclonic (upwelling, ∼ 13 months old) and an anticyclonic (downwelling, ∼ 2 months old) eddy as well as in an uninfluenced background situation in the oligotrophic southeastern Me
Externí odkaz:
https://doaj.org/article/94a5dde2e488440eb1514ce96b173623
Autor:
Geoffrey W Meissner, Aljoscha Nern, Zachary Dorman, Gina M DePasquale, Kaitlyn Forster, Theresa Gibney, Joanna H Hausenfluck, Yisheng He, Nirmala A Iyer, Jennifer Jeter, Lauren Johnson, Rebecca M Johnston, Kelley Lee, Brian Melton, Brianna Yarbrough, Christopher T Zugates, Jody Clements, Cristian Goina, Hideo Otsuna, Konrad Rokicki, Robert R Svirskas, Yoshinori Aso, Gwyneth M Card, Barry J Dickson, Erica Ehrhardt, Jens Goldammer, Masayoshi Ito, Dagmar Kainmueller, Wyatt Korff, Lisa Mais, Ryo Minegishi, Shigehiro Namiki, Gerald M Rubin, Gabriella R Sterne, Tanya Wolff, Oz Malkesman, FlyLight Project Team
Publikováno v:
eLife, Vol 12 (2023)
Precise, repeatable genetic access to specific neurons via GAL4/UAS and related methods is a key advantage of Drosophila neuroscience. Neuronal targeting is typically documented using light microscopy of full GAL4 expression patterns, which generally
Externí odkaz:
https://doaj.org/article/78a91ebc754d4c3798f4ad739340bae0