Zobrazeno 1 - 10
of 211
pro vyhledávání: '"M, Quintas"'
Autor:
Jacqueline Alves Leite, Elisa Pôças, Gisele Silva Maia, Leandro Barbosa, Luis Eduardo M. Quintas, Elisa Mitiko Kawamoto, Maria Luiza Correia da Silva, Cristoforo Scavone, Luciana E. Drumond de Carvalho
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The Na+/K+-ATPase is an integral membrane ion pump, essential to maintaining osmotic balance in cells in the presence of cardiotonic steroids; more specifically, ouabain can be an endogenous modulator of the Na+/K+-ATPase. Here, we conducted a system
Externí odkaz:
https://doaj.org/article/7fba19639a3945f4b1658006ac628cea
Autor:
M. Quintas-Neves, J. Saraiva
Publikováno v:
AJNR. American journal of neuroradiology. 43(11)
Publikováno v:
Revista Portuguesa de Pneumologia (English Edition), Vol 22, Iss 6, Pp 331-336 (2016)
A worldwide rise in weight and obesity is taking place, associated with an increase in several comorbid conditions, such as Obstructive Sleep Apnea (OSA). Bariatric surgery is an effective treatment approach for obesity, with resultant improvement in
Externí odkaz:
https://doaj.org/article/ad2e6aa79aa94abd8d98e5048eb8d6dd
Autor:
Deyse C. M. Carvalho, Luiz Henrique Agra Cavalcante-Silva, Éssia de A. Lima, José G. F. M. Galvão, Anne K. de A. Alves, Priscilla R. O. Feijó, Luís E. M. Quintas, Sandra Rodrigues-Mascarenhas
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Cardiotonic steroids, such as ouabain and digoxin, are known to bind to Na+/K+-ATPase and to promote several biological activities, including anti-inflammatory activity. However, there are still no reports in the literature about inflammation and mar
Externí odkaz:
https://doaj.org/article/af0f7cf41ce64ca48768df943476bc38
Autor:
Jhonatha Mota Teixeira-Cruz, Marcelo Abrahão Strauch, Marcos Monteiro-Machado, Matheus Silva Tavares-Henriques, João Alfredo de Moraes, Luís Eduardo Ribeiro da Cunha, Rui Seabra Ferreira, Benedito Barraviera, Luis Eduardo M. Quintas, Paulo A. Melo
Publikováno v:
Toxins, Vol 13, Iss 1, p 30 (2021)
Massive, Africanized honeybee attacks have increased in Brazil over the years. Humans and animals present local and systemic effects after envenomation, and there is no specific treatment for this potentially lethal event. This study evaluated the ab
Externí odkaz:
https://doaj.org/article/803f6d5e902344669ec50fa576fdd110
Autor:
Sayonarah C. Rocha, Luis Eduardo M. Quintas, Natasha Paixão, Vanessa Faria Cortes, Gisele Capanema de Oliveira, Silmara L.G. Alves, José A.F.P. Villar, Leandro A. Barbosa, Marco Túlio C. Pessôa, François Noël, Miliane Alves da Silva Lopes
Publikováno v:
The Journal of Membrane Biology. 254:487-497
Na,K-ATPase (NKA) and cardiotonic steroids (CTS) have shown potent cytotoxic and anticancer effects. Here, we have synthesized a series of CTS digoxin derivatives (γ-benzylidene) with substitutions in the lactone ring and evaluated the cytotoxicity
Akademický článek
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Autor:
Paula Fernanda Kinoshita, Jacqueline Alves Leite, Ana Maria Marques Orellana, Andrea Rodrigues Vasconcelos, Luis Eduardo M Quintas, Elisa Mitiko Kawamoto, Cristoforo eScavone
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Decreased Na+,K+-ATPase (NKA) activity causes energy deficiency, which is commonly observed in neurodegenerative diseases. The NKA is constituted of three subunits: α, β and γ, with four distinct isoforms of the catalytic α subunit (α1-4). Genet
Externí odkaz:
https://doaj.org/article/06fa27ff105c41a79529f428e56b0d0a
Autor:
Luciana S. Amaral, Jainne Martins Ferreira, Danilo Predes, José Garcia Abreu, François Noël, Luis Eduardo M. Quintas
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2769 (2018)
Bufadienolides are cardiotonic steroids (CTS) identified in mammals. Besides Na+/K+-ATPase inhibition, they activate signal transduction via protein–protein interactions. Diversity of endogenous bufadienolides and mechanisms of action may indicate
Externí odkaz:
https://doaj.org/article/11c1dbbc33d949d4a15e070d7a64422f
Autor:
Anderson Domingues Corrêa, Rodrigo Siqueira-Batista, Luis Eduardo M. Quintas, Romulo Siqueira-Batista
Publikováno v:
História, Ciências, Saúde: Manguinhos, Vol 13, Iss 1, Pp 13-31 (2006)
O presente texto retoma as discussões iniciadas no artigo "Simila Similibus Curentur: notação histórica da medicina homeopática" (1997), revendo desvios conceituais de outrora e aprofundando o debate histórico sobre as origens da homeopatia. A
Externí odkaz:
https://doaj.org/article/3337dfb082b74d05bd243ad54b17e5c7