Parental perspectives on the awareness and delivery of preconception care

Autor: M. Poels, M. P. H. Koster, A. Franx, H. F. van Stel

Publikováno v: BMC Pregnancy and Childbirth, Vol 17, Iss 1, Pp 1-9 (2017)

Abstract Background The attention for Preconception Care (PCC) has grown substantially in recent years, yet the implementation of PCC appears challenging as uptake rates remain low. The objective of this study was to assess parental perspectives on h

Externí odkaz: https://doaj.org/article/8a29ffbfe10e44fcbdf8410c044ffa9c

MicroRNA-216a is essential for cardiac angiogenesis

Autor: Rio P. Juni, Jordy M.M. Kocken, Ricardo C. Abreu, Lara Ottaviani, Tim Davalan, Burcu Duygu, Ella M. Poels, Aliaksei Vasilevich, Jana C. Hegenbarth, Mahesh Appari, Nicole Bitsch, Serve Olieslagers, Dorien M. Schrijvers, Monika Stoll, Joerg Heineke, Jan de Boer, Leon J. de Windt, Paula A. da Costa Martins

Publikováno v: Juni, R P, Kocken, J M M, Abreu, R C, Ottaviani, L, Davalan, T, Duygu, B, Poels, E M, Vasilevich, A, Hegenbarth, J C, Appari, M, Bitsch, N, Olieslagers, S, Schrijvers, D M, Stoll, M, Heineke, J, de Boer, J, de Windt, L J & da Costa Martins, P A 2023, ' MicroRNA-216a is essential for cardiac angiogenesis ', Molecular Therapy, vol. 31, no. 6, pp. 1807-1828 . https://doi.org/10.1016/j.ymthe.2023.04.007
Molecular Therapy, 31(6), 1807-1828. Nature Publishing Group

While it is experimentally supported that impaired myocardial vascularization contributes to a mismatch between myocardial oxygen demand and supply, a mechanistic basis for disruption of coordinated tissue growth and angiogenesis in heart failure rem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4cdfbed4c34e65e260ef80ffb25f52
https://research.vumc.nl/en/publications/afc667a8-f509-4264-b38a-61a3f329b22d

The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload

Autor: G J du Marchie Sarvaas, Ella M. Poels, Paula A. da Costa Martins, Rudolphus Berger, Lara Ottaviani, C Dos Remedios, F S De Man, L. J. de Windt, Anne-Marie C. Koop, André Lourenço, K W Van De Kolk, Diana S. Nascimento, Jordy M. M. Kocken, Raquel Figuinha Videira, P. Mendes-Ferreira, Aida Llucià-Valldeperas, Inês Falcão-Pires

Publikováno v: Cardiovascular Research, 118(12), 2688-2702. Oxford University Press
Videira, R F, Koop, A M C, Ottaviani, L, Poels, E M, Kocken, J M M, Dos Remedios, C, Mendes-Ferreira, P, van de Kolk, K W, du Marchie Sarvaas, G J, Lourenço, A, Llucià-Valldeperas, A, Nascimento, D AS, de Windt, L J, de Man, F S, Falcão-Pires, I, Berger, R M F & da Costa Martins, P A 2022, ' The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload ', Cardiovascular Research, vol. 118, no. 12, pp. 2688-2702 . https://doi.org/10.1093/cvr/cvab299, https://doi.org/10.1093/cvr/cvab299

Aims Research on the pathophysiology of right ventricular (RV) failure has, in spite of the associated high mortality and morbidity, lagged behind compared to the left ventricle (LV).Previous work from our lab revealed that the embryonic basic helix-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca90fa70a91fff405ab555b55989501f
https://doi.org/10.1093/cvr/cvab299

Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice.

Autor: Ella M Poels, Nicole Bitsch, Jos M Slenter, M Eline Kooi, Chiel C de Theije, Leon J de Windt, Vanessa P M van Empel, Paula A da Costa Martins

Publikováno v: PLoS ONE, Vol 9, Iss 4, p e92983 (2014)

Pulmonary hypertension and subsequent right ventricular (RV) failure are associated with high morbidity and mortality. Prognosis is determined by occurrence of RV failure. Currently, adequate treatment for RV failure is lacking. Further research into

Externí odkaz: https://doaj.org/article/e968aad005734b4081a442f1c9d50075

P4996The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload

Autor: L. J. de Windt, Lara Ottaviani, Rudolphus Berger, Anne-Marie C. Koop, K W Van De Kolk, André Lourenço, Ella M. Poels, P.A. da Costa Martins, Raquel Figuinha Videira, Diana S. Nascimento, Inês Falcão-Pires

Publikováno v: European Heart Journal. 40

Introduction Heart and neural crest derivatives expressed-2 (Hand2) has been identified as an important embryonic basic helix-loop-helix-transcription factor, with different functions in the development of the first and second heart field, from which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfe92b4d0051ada0e5fa528e3ba5591c
https://doi.org/10.1093/eurheartj/ehz746.0174