Zobrazeno 1 - 10
of 3 369
pro vyhledávání: '"M, Pederson"'
Autor:
Erin Sheffels PhD, Mariam Khalil BS, Kristen Hutchison BS, Nicole J. Hardy MS, Ranita Tarchand MS, John M. Pederson BS, Anjani Parikh MPH, Michael Blauth MD, PhD
Publikováno v:
Geriatric Orthopaedic Surgery & Rehabilitation, Vol 15 (2024)
Introduction Femoral neck fractures (FNF) represent a significant challenge in orthopedic practice, demanding prompt intervention to restore function and mobility in affected individuals. Numerous surgical interventions have been developed to address
Externí odkaz:
https://doaj.org/article/8d015c5e728043528f02de2d3f3fa014
Autor:
Leila Hosseinzadeh, Zoya Kikhtyak, Geraldine Laven-Law, Stephen M. Pederson, Caroline G. Puiu, Clive S. D’Santos, Elgene Lim, Jason S. Carroll, Wayne D. Tilley, Amy R. Dwyer, Theresa E. Hickey
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-28 (2024)
Abstract Background The androgen receptor (AR) is a tumor suppressor in estrogen receptor (ER) positive breast cancer, a role sustained in some ER negative breast cancers. Key factors dictating AR genomic activity in a breast context are largely unkn
Externí odkaz:
https://doaj.org/article/d7b51d564a0b4733aace68da8648cf13
Autor:
Jonghoo Sung, Kate R. Barratt, Stephen M. Pederson, Chantal Chenu, Ines Reichert, Gerald J. Atkins, Paul H. Anderson, Peter J. Smitham
Publikováno v:
Bone & Joint Research, Vol 12, Iss 10, Pp 657-666 (2023)
Aims: Impaired fracture repair in patients with type 2 diabetes mellitus (T2DM) is not fully understood. In this study, we aimed to characterize the local changes in gene expression (GE) associated with diabetic fracture. We used an unbiased approach
Externí odkaz:
https://doaj.org/article/744044a5c9934d508ce9a8976a417233
Autor:
Lachlan Baer, Karissa Barthelson, John H Postlethwait, David L Adelson, Stephen M Pederson, Michael Lardelli
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 2, p e1011868 (2024)
In comparisons between mutant and wild-type genotypes, transcriptome analysis can reveal the direct impacts of a mutation, together with the homeostatic responses of the biological system. Recent studies have highlighted that, when the effects of hom
Externí odkaz:
https://doaj.org/article/d9c21ff053ad40258f64fe602bea9ede
Autor:
Ruijia Chen, Jingxuan Wang, Annie M. Pederson, Aric A. Prather, Andrew K. Hirst, Sarah Ackley, Emily Hokett, Kristen M. George, Dan Mungas, Elizabeth Rose Mayeda, Paola Gilsanz, Sebastien Haneuse, Rachel A. Whitmer, M. Maria Glymour
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION The prevalence of poor sleep quality and sleep apnea differs by race and ethnicity and may contribute to racial disparities in cognitive aging. We investigated whether sleep quality and sleep apnea risk were associated with cogn
Externí odkaz:
https://doaj.org/article/68ac5a47f0b84adabe15e655dc8e2d7b
Autor:
Ying Y. Wong, Jessica E. Harbison, Christopher M. Hope, Batjargal Gundsambuu, Katherine A. Brown, Soon W. Wong, Cheryl Y Brown, Jennifer J. Couper, Jimmy Breen, Ning Liu, Stephen M. Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C. Barry
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Epigenetic features such as DNA accessibility dictate transcriptional regulation in a cell type- and cell state- specific manner, and mapping this in health vs. disease in clinically relevant material is opening the door to new mechanistic i
Externí odkaz:
https://doaj.org/article/a56eda72cadc4472b5afe216794b04ff
Autor:
Aaron E. Casey, Wenjun Liu, Leanne K. Hein, Timothy J. Sargeant, Stephen M. Pederson, Ville-Petteri Mäkinen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Autophagy is an intracellular recycling process that degrades harmful molecules and enables survival during starvation, with implications for diseases including dementia, cancer and atherosclerosis. Previous studies demonstrate how a limited
Externí odkaz:
https://doaj.org/article/fdb2a38e9a854cb4ab315aec591c7e90
Autor:
Sebastian Sanchez, Meredith Hickerson, Rishi R. Patel, Dana Ghazaleh, Ranita Tarchand, Geeta S. Paranjape, Holly Pope, Santiago Ortega‐Gutierrez, John M. Pederson, David Hasan, Madhavan L. Raghavan, Edgar A. Samaniego
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 2 (2023)
Background It is unclear what morphological features of brain aneurysms are better at predicting risk of rupture. We conducted a meta‐analysis to analyze the best morphological determinants of rupture status. Methods The Nested Knowledge platform w
Externí odkaz:
https://doaj.org/article/5ed7226ff996462a89c3b59cb110aec2
Autor:
Christopher Leibold, DO, Ryan Falbo, DO, Anil Gupta, MD, Richard Miller, DO, John M. Pederson, BS, Manashree Malpe, PhD
Publikováno v:
OTA International, Vol 5, Iss 3, p e204 (2022)
Abstract. Objective:. To compare technical, clinical, and safety outcomes among hip fracture patients treated with procedures supplemented by general anesthesia (GA) or spinal/regional anesthesia (S/R). Data sources:. We searched for original studies
Externí odkaz:
https://doaj.org/article/46cd561f28ed477eb4cccac4d1c73055
Autor:
David Kudrow, Roger K. Cady, Brent Allan, Susan M. Pederson, Joe Hirman, Lahar R. Mehta, Barbara A. Schaeffler
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody recently approved in the United States for preventive treatment of migraine in adults, was found to be well tolerated in double-blind, placebo-controlled stu
Externí odkaz:
https://doaj.org/article/7ae3b25ea70f489ca35e15e25c6fbe79