Zobrazeno 1 - 10
of 42
pro vyhledávání: '"M, Pawula"'
Publikováno v:
Chromatographia. 47:667-672
The chromatographic behaviour of a series of morphine-based opiates has been investigated using a porous graphitic carbon packing material at acid and alkaline pH. The effects of mobile phase pH, mobile phase organic percentage, column temperature an
Autor:
S.S. Davis, Nidal F. Farraj, Paul N. Shaw, A.N. Fisher, Lisbeth Illum, M. Pawula, David A. Barrett
Publikováno v:
Biopharmaceutics & Drug Disposition. 17:717-724
The pharmacokinetics of morphine-6-glucuronide (M6G) after both intravenous dosing and nasal administration were studied in sheep. The nasal formulation consisted of M6G in combination with an absorption promoting delivery system in the form of chito
Publikováno v:
Scopus-Elsevier
AIMS--To compare the safety and efficacy of two loading doses of diamorphine in 27 ventilated newborn infants in a randomised double blind trial. METHODS--Fifty or 200 mcg/kg were infused intravenously over 30 minutes, followed by a 15 mcg/kg/hour co
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 653:106-111
A rapid and sensitive HPLC method has been developed for the determination of codeine, norcodeine and morphine in small volumes of a biological matrix, using a cyanopropyl column and a combination of coulometric and UV detection. The compounds were i
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 719(1-2)
A sensitive and specific LC–MS–MS assay has been developed and validated for barnidipine (1-benzyl-3-pyrrolidinyl)methyl-2,6-dimethyl-4( m -nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate). The assay involves a simple and rapid solid-phase ext
Publikováno v:
Biopharmaceuticsdrug disposition. 17(8)
The pharmacokinetics of morphine-6-glucuronide (M6G) after both intravenous dosing and nasal administration were studied in sheep. The nasal formulation consisted of M6G in combination with an absorption promoting delivery system in the form of chito
Publikováno v:
Scopus-Elsevier
1. The pharmacokinetics of morphine, morphine-6-glucuronide (M6G) and morphine-3-glucuronide (M3G) were studied in 19 ventilated newborn infants (24-41 weeks gestation) who were given a loading dose of 50 micrograms kg-1 or 200 micrograms kg-1 of dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2659eabf9d45b490b7d8c1155e25a0f
https://europepmc.org/articles/PMC2042627/
https://europepmc.org/articles/PMC2042627/
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 11(4-5)
A new, simple and rapid extraction procedure coupled with a combined coulometric-fluorescence HPLC assay is described for the simultaneous determination of morphine (M) and morphine-3-glucuronide (M3G), morphine-6-glucuronide (M6G), and normorphine (
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