Zobrazeno 1 - 10
of 48
pro vyhledávání: '"M, Pausa"'
Publikováno v:
Molecular Immunology. 36:261-268
The function of the endothelial cells can be modulated by humoral factors present in the circulation and in the extravascular fluid, including proteins of the complement system. This review examines the multiple interactions between the complement sy
Publikováno v:
The Journal of Experimental Medicine
The terminal components of the complement system contribute to host defense by forming the multiprotein membrane attack complex (MAC) which is responsible for cell lysis and several noncytotoxic effects. Most of the complement proteins are synthesize
Autor:
Alberto Mantovani, Luca De Gioia, Barbara Bottazzi, Valérie Vouret-Craviari, Giuseppe Peri, Martino Introna, Elisabetta Gianazza, Mario Salmona, Francesco Tedesco, Cinzia D'Ettorre, Antonio Bastone, Cristian Matteucci, Aldo Tagliabue, Fabio Spreafico, M. Pausa
Publikováno v:
Journal of Biological Chemistry. 272:32817-32823
PTX3 is a prototypic long pentraxin consisting of a C-terminal 203-amino acid pentraxin-like domain coupled with an N-terminal 178-amino acid unrelated portion. The present study was designed to characterize the structure and ligand binding propertie
Autor:
Tom Eirik Mollnes, Leprini A, Arcangelo Nocera, Sergio Barocci, M. Pausa, Francesco Tedesco, O Radillo, M Pocecco, Umberto Valente, C. Betterle
Publikováno v:
Clinical Immunology and Immunopathology. 79:217-223
Forty-one sera of patients with IDDM (insulin-dependent diabetes mellitus) containing complement-fixing islet cell antibodies were analyzed for their ability to activate TCC (terminal complement complex). Eighteen sera were found to promote depositio
To investigate the effect of the terminal complement complex (TCC) on the central nervous system, we injected both the cytolytically active and the inactive complexes into the lateral ventricle of rats. Both complexes promoted accumulation of leukocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea2a1fe7e244d571d86002da53e06f1
https://hdl.handle.net/11368/1701723
https://hdl.handle.net/11368/1701723
Autor:
Francesco Tedesco, Elena Vecile, Roberta Bulla, Aldo Dobrina, Elisabetta Ferrero, Alberto Mantovani, Fabio Fischetti, M. Pausa
Publikováno v:
Blood. 99(1)
Intravital microscopy was used to monitor leukocyte traffic across rat mesenteric postcapillary venules induced by the inactive terminal complement (C) complex (iTCC) topically applied to ileal mesentery. Leukocytes started rolling within 15 minutes
Autor:
G, Barbano, F, Cappa, I, Prigione, F, Tedesco, M, Pausa, R, Gugliemino, V, Pistoia, R, Gusmano, F, Perfumo
Publikováno v:
Advances in peritoneal dialysis. Conference on Peritoneal Dialysis. 15
The CD59 membrane protein confers protection from C5b-9-mediated cell lysis. Because evidence exists for complement (C) activation and generation of C5b-9 in the peritoneal cavity during chronic peritoneal dialysis (CPD), we investigated, on mesothel
SUMMARYThe level of the terminal complement components secreted by human umbilical vein endothelial cells (HUVEC) was measured by a sensitive ELISA which allows the detection of 30–50 pg/ml of these components. C7 was the only terminal component de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087ce45263a677baea0b3efbed8fca78
http://hdl.handle.net/11368/1701715
http://hdl.handle.net/11368/1701715
Publikováno v:
Recenti progressi in medicina. 88(9)
The mother establishes with the fetus a special interaction in pregnancy allowing his normal survival in spite of the different HLA antigens. The main factors contributing to these favourable conditions for the fetus are an efficient local immunosupp
Autor:
B, Bottazzi, V, Vouret-Craviari, A, Bastone, L, De Gioia, C, Matteucci, G, Peri, F, Spreafico, M, Pausa, C, D'Ettorre, E, Gianazza, A, Tagliabue, M, Salmona, F, Tedesco, M, Introna, A, Mantovani
Publikováno v:
The Journal of biological chemistry. 272(52)
PTX3 is a prototypic long pentraxin consisting of a C-terminal 203-amino acid pentraxin-like domain coupled with an N-terminal 178-amino acid unrelated portion. The present study was designed to characterize the structure and ligand binding propertie