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A randomized, double-blind, placebo-controlled trial of antidepressants in Parkinson disease

Autor: I H, Richard, M P, McDermott, R, Kurlan, J M, Lyness, P G, Como, N, Pearson, S A, Factor, J, Juncos, C, Serrano Ramos, M, Brodsky, C, Manning, L, Marsh, L, Shulman, H H, Fernandez, K J, Black, M, Panisset, C W, Christine, W, Jiang, C, Singer, S, Horn, R, Pfeiffer, D, Rottenberg, J, Slevin, L, Elmer, D, Press, H C, Hyson, W, McDonald, Katie, Kompoliti

Publikováno v: Neurology. 78:1229-1236

Objective: To evaluate the efficacy and safety of a selective serotonin reuptake inhibitor (SSRI) and a serotonin and norepinephrine reuptake inhibitor (SNRI) in the treatment of depression in Parkinson disease (PD). Methods: A total of 115 subjects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47bf5e71f642d58c1ccba36919ef5f6
https://doi.org/10.1212/wnl.0b013e3182516244

Cerebrolysin in Alzheimer's disease: a randomized, double-blind, placebo-controlled trial with a neurotrophic agent

Autor: Manfred Windisch, H. Moessler, M. Panisset, Serge Gauthier

Publikováno v: Journal of Neural Transmission. 109:1089-1104

Cerebrolysin (Cere) is a compound with neurotrophic activity. It has been shown to be effective in the treatment of Alzheimer's disease (AD) in earlier trials. In this multicenter, randomized, double-blind, placebo-controlled, parallel-group study, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92f54b94017bdfaf4ddf5089e207136
https://doi.org/10.1007/s007020200092

R1514Q substitution in Lrrk2 is not a pathogenic Parkinson's disease mutation

Autor: Karen Williams, Carolyn Peterson, S. Narayan, Margaret F. Turk, Julie H. Carter, C. Schell, Carlos Singer, Chad W. Christine, Paul J. Tuite, Robyn Schacherer, J. Whetteckey, S. Phipps, Diane K. Marek, William C. Nichols, John M. Bertoni, A. H. Rajput, Kenneth Marek, An Tran, P. Ryan, J. Hevezi, Joan Werner, Kelvin L. Chou, S. Chouinard, James Sutton, Margaret C. Lannon, T. Ajax, Joan Young, Deborah Judd, L. Zelaya, David Grimes, Magali Fernandez, Theresa A. Zesiewicz, Mark Stacy, Peggy Gray, Debra Berry, Michael J. Aminoff, C. Horn, C. Costan-Toth, J. Mannetter, Patricia Simpson, Susan Rolandelli, Tatiana Foroud, T. Tra, S. Wilson, Judith Dobson, Nestor Galvez-Jimenez, Donna Schwieterman, Shirley Uy, K. Price, J. Wojcieszek, Anette Nieves, Paul Atchison, Susan Bennett, L. Klassen, A. Podichetty, Vincent Calabrese, Becky Dunlop, D. Kamp, Holly Delgado, Sandra Roque, Maureen A. Leehey, Richard Camicioli, Julie So, Jayaraman Rao, Kelly E. Lyons, Kapil D. Sethi, A. Wang, Lynn Marlor, David Oakes, S. Culver, Juan Sanchez-Ramos, L. Woodward, J. Danielson, Jeannine Petit, Joann Belden, E. Licari, M. Meacham, Deborah Fontaine, Sharon Evans, C. Stone, S. Morehouse, Christopher F. O'Brien, G. Podskalny, J. Fraser, Anthony E. Lang, W.R. Wayne Martin, Carmen Serrano, H. Poiffaut, Stewart A. Factor, Joanne Wojcieszek, S. Belber, L. Davis, C. Allen, J. Hall, Judy Richman, Joseph Jankovic, Carson Reider, Stephen G. Reich, Stephanie Thomas, Kathy Davis, Richard B. Dewey, Karen Marder, T. Demarcaida, A. Kaczmarek, Lauren Seeberger, C. Halter, Mary Lou Klimek, Donald S. Higgins, Miodrag Velickovic, Joanna Hamann, Eric Siemers, E. Ohmann, C. Dingmann, Galit Kleiner-Fisman, Shari Niswonger, Theresa Derian, Maryan DeAngelis, Aileen Shinaman, Tilak Mendis, M. Rundle, Susan Mendick, L. Giffin, Karen Blindauer, Paul Gordon, Andrew Feigin, L. Shulman, Maureen Cook, Brian Wulbrecht, Rajesh Pahwa, T. Foroud, Un Jung Kang, Arthur Watts, Oksana Suchowersky, C. Joubert, J. Vo, Mandar Jog, M. Panisset, Roberta Winnick, Ronald F. Pfeiffer, Barbara Shannon, Jean P. Hubble, Clifford W. Shults, T. Gales, Tanya Simuni, M. Wolff, Hubert H. Fernandez, Pam Andrews, Karyn Boyar, Brad A. Racette, Vicki Hunt, Christine Hunter, Daniel D. Truong, L. Good, Robert L. Rodnitzky, P. Rodriguez, Sandra K. Kostyk, T. Shirley, Cheryl Halter, Peter A LeWitt, W. Weiner, Ryan J. Uitti, Lisa Scollins, Marc L. Gordon, J. Carpenter, Alice Rudolph, Lewis Sudarsky, Robert A. Hauser, Cliff Shults, Bala V. Manyam, Francis O. Walker, Juliette Harris, Marguerite Wieler, K. Dustin, Kelli Williamson, Brenda Pfeiffer, William C. Koller, Frederick J. Marshall, V. Hagen, A. Campbell, B. Hutchinson, L. Elmer, Anja Rudolph, K. Haas, Tori Ross, Rachel Saunders-Pullman, Nathan Pankratz, E. Aiken, Mariann DiMinno, Peggy Roberge, Arif Dalvi, B. Hayward, Mayank Pathak, David Simon, Michael W. Pauciulo, Holly A. Shill, M. Marotta-Kollarus, K. Ligon, Alok Sahay, Joseph H. Friedman, Neal Hermanowicz, E. Julian-Baros, Irenita Gardiner, N. Luong, Danna Jennings, R. Kurlan, P. M. Conneally

Publikováno v: Movement Disorders. 22:254-256

Mutations in LRRK2 were first reported as causing Parkinson's disease (PD) in late 2004. Since then, approximately a dozen LRRK2 substitutions have been identified that are believed to be pathogenic mutations. The substitution of adenine for guanine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c48f0117672933936e1f3bb8ac731d4
https://doi.org/10.1002/mds.21233

Visuo-spatial dysgnosia and Balint's syndrome as major symptoms of probable Alzheimer's disease

Autor: F. Boiler, M. Agostini, M. Panisset, P. Davous

Publikováno v: European Journal of Neurology. 3:519-527

We describe three patients, respectively 57-, 54- and 55-years-old at onset of the disease, who developed over many years a progressive cortical visual dysfunction without overt dementia. At onset, the visual symptoms were mainly a visuo-spatial dysg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::023e82a3b17d0f0dd9d21aeaf29d612d
https://doi.org/10.1111/j.1468-1331.1996.tb00267.x