Zobrazeno 1 - 10
of 218
pro vyhledávání: '"M, Pützer"'
Autor:
Alf Spitschak, Prabir Dhar, Krishna P. Singh, Rosaely Casalegno Garduño, Shailendra K. Gupta, Julio Vera, Luca Musella, Nico Murr, Anja Stoll, Brigitte M. Pützer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Melanoma is a metastatic, drug-refractory cancer with the ability to evade immunosurveillance. Cancer immune evasion involves interaction between tumor intrinsic properties and the microenvironment. The transcription factor E2F1 is a key driver of tu
Externí odkaz:
https://doaj.org/article/c657325e04404d39822a0b0f1f23ff5d
Publikováno v:
Viruses, Vol 16, Iss 3, p 387 (2024)
Viral vectors are gene transfer tools assembled from the backbones of naturally occurring viruses [...]
Externí odkaz:
https://doaj.org/article/706a0a036d6d40db95c25dfa2ac76a8b
Autor:
Brigitte M. Pützer, Kanaga Sabapathy
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/4c033cdce19346319ba325f65393aa33
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 83 (2022)
Cancer cells have a remarkable ability to evade recognition and destruction by the immune system. At the same time, cancer has been associated with chronic inflammation, while certain autoimmune diseases predispose to the development of neoplasia. Al
Externí odkaz:
https://doaj.org/article/ad0b04cfaba54d56a10813709ec40325
Autor:
Stella Logotheti, Christin Richter, Nico Murr, Alf Spitschak, Stephan Marquardt, Brigitte M. Pützer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The transcription factor p73 is a structural and functional homolog of TP53, the most famous and frequently mutated tumor-suppressor gene. The TP73 gene can synthesize an overwhelming number of isoforms via splicing events in 5′ and 3′ ends and a
Externí odkaz:
https://doaj.org/article/9dc88289fc5d4874883451a05711f46d
Autor:
Stephan Marquardt, Athanasia Pavlopoulou, Işıl Takan, Prabir Dhar, Brigitte M. Pützer, Stella Logotheti
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cancer acquires metastatic potential and evolves via co-opting gene regulatory networks (GRN) of embryonic development and tissue homeostasis. Such GRNs are encoded in the genome and frequently conserved among species. Considering that all metazoa ha
Externí odkaz:
https://doaj.org/article/22f0e2ea2f2e45ff9e50d25d381657fd
Autor:
Christin Richter, Stephan Marquardt, Fanghua Li, Alf Spitschak, Nico Murr, Berdien A. H. Edelhäuser, George Iliakis, Brigitte M. Pützer, Stella Logotheti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Bladder cancer progression has been associated with dysfunctional repair of double-strand breaks (DSB), a deleterious type of DNA lesions that fuel genomic instability. Accurate DSB repair relies on two distinct pathways, homologo
Externí odkaz:
https://doaj.org/article/22f82b4a638340d89026eb39128394df
Autor:
Faiz M. Khan, Stephan Marquardt, Shailendra K. Gupta, Susanne Knoll, Ulf Schmitz, Alf Spitschak, David Engelmann, Julio Vera, Olaf Wolkenhauer, Brigitte M. Pützer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Deregulation of E2F family transcription factors is associated with cancer progression and metastasis. Here, the authors construct a map of the regulatory network around the E2F family, and using gene expression profiles, identify tumour type-specifi
Externí odkaz:
https://doaj.org/article/6feb9a206c964085ae20896ed0722b38
Autor:
Brigitte M. Pützer, Olaf Wolkenhauer, Faiz M. Khan, David Engelmann, Xin Lai, Ulf Schmitz, Julio Vera
PDF file - 106K, Model definition and parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f85546c8ac4b735fc21ea8b4fbe9d3
https://doi.org/10.1158/0008-5472.22397388.v1
https://doi.org/10.1158/0008-5472.22397388.v1
Cancer stem–like cells (CSC) have been proposed to promote cancer progression by initiating tumor growth at distant sites, suggesting that stem-like cell features can support metastatic efficiency. Here, we demonstrate that oncogenic DNp73, a domin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c0e54af99a3ab2dc3486e018508826
https://doi.org/10.1158/0008-5472.c.6507860
https://doi.org/10.1158/0008-5472.c.6507860