Zobrazeno 1 - 10
of 1 184
pro vyhledávání: '"M, O'Donovan"'
Autor:
Abdul-rizaq Hamoud, Khaled Alganem, Sean Hanna, Michael Morran, Nicholas Henkel, Ali S. Imami, William Ryan, Smita Sahay, Priyanka Pulvender, Austin Kunch, Taylen O. Arvay, Jarek Meller, Rammohan Shukla, Sinead M. O’Donovan, Robert McCullumsmith
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Protein kinases are critical components of a myriad biological processes and strongly associated with various diseases. While kinase research has been a point of focus in biomedical research for several decades, a large portion of the kinome
Externí odkaz:
https://doaj.org/article/0fe77c7a32824f5db32b05dec26eb13a
Publikováno v:
Journal of Dairy Science, Vol 107, Iss 4, Pp 2231-2240 (2024)
ABSTRACT: Improved nitrogen utilization of dairy production systems should improve not only the economic output of the systems but also the environmental metrics. One strategy to improve efficiency is through breeding programs. Improving a trait thro
Externí odkaz:
https://doaj.org/article/6e3b2c5caa704af4aa41de9366aebe4d
Autor:
Jake Valeri, Charlotte Stiplosek, Sinead M. O’Donovan, David Sinclair, Kathleen A. Grant, Ratna Bollavarapu, Donna M. Platt, Craig A. Stockmeier, Barbara Gisabella, Harry Pantazopoulos
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Contextual triggers are significant factors contributing to relapse in substance use disorders (SUD). Emerging evidence points to a critical role of extracellular matrix (ECM) molecules as mediators of reward memories. Chondroitin sulfate pr
Externí odkaz:
https://doaj.org/article/304450224fd54ef7b09e590ab5499d6c
Autor:
Gabriele Chelini, Hadi Mirzapourdelavar, Peter Durning, David Baidoe-Ansah, Manveen K. Sethi, Sinead M. O’Donovan, Torsten Klengel, Luigi Balasco, Cristina Berciu, Anne Boyer-Boiteau, Robert McCullumsmith, Kerry J. Ressler, Joseph Zaia, Yuri Bozzi, Alexander Dityatev, Sabina Berretta
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114112- (2024)
Summary: Recent findings show that effective integration of novel information in the brain requires coordinated processes of homo- and heterosynaptic plasticity. In this work, we hypothesize that activity-dependent remodeling of the peri-synaptic ext
Externí odkaz:
https://doaj.org/article/21eb77a4d1ef4429b4c1a9780261c8f6
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 12, Pp 8871-8884 (2023)
ABSTRACT: Reducing nitrogen pollution while maintaining milk production is a major challenge of dairy production. One of the keys to delivering on this challenge is to improve the efficiency of how dairy cows use nitrogen. Thus, estimating the nitrog
Externí odkaz:
https://doaj.org/article/f30e99e7f70c48c7b2a8d75da15c144a
Autor:
Smita Sahay, Emily A. Devine, Christina F.-A. Vargas, Robert E. McCullumsmith, Sinead M. O’Donovan
Publikováno v:
Cells, Vol 13, Iss 19, p 1657 (2024)
Schizophrenia is a neuropsychiatric illness characterized by altered neurotransmission, in which adenosine, a modulator of glutamate and dopamine, plays a critical role that is relatively unexplored in the human brain. In the present study, postmorte
Externí odkaz:
https://doaj.org/article/833e0b4929eb46729b2bc3565f62e9f2
Autor:
Smita Sahay, Priyanka Pulvender, Madhu Vishnu Sankar Reddy Rami Reddy, Robert E. McCullumsmith, Sinead M. O’Donovan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8266 (2024)
The disruption of brain energy metabolism, leading to alterations in synaptic signaling, neural circuitry, and neuroplasticity, has been implicated in severe mental illnesses such as schizophrenia, bipolar disorder, and major depressive disorder. The
Externí odkaz:
https://doaj.org/article/3abb94532a054e5a980f16f8626ea399
Publikováno v:
Irish Journal of Agricultural and Food Research, Vol 62, Iss 1, Pp 32-43 (2023)
Little data are currently available on either the dry matter (DM) production of perennial ryegrass (PRG) swards as they age beyond 5 yr (i.e. permanent pasture) or the performance of PRG varieties on commercial grassland farms. Previous work has gene
Externí odkaz:
https://doaj.org/article/2defe16980584f6e8d0b2714be413721
Autor:
Catherine O’Reilly, Ghjuvan M. Grimaud, Mairéad Coakley, Paula M. O’Connor, Harsh Mathur, Veronica L. Peterson, Ciara M. O’Donovan, Peadar G. Lawlor, Paul D. Cotter, Catherine Stanton, Mary C. Rea, Colin Hill, R. Paul Ross
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Nisin is a broad spectrum bacteriocin used extensively as a food preservative that was identified in Lactococcus lactis nearly a century ago. We show that orally-ingested nisin survives transit through the porcine gastrointestinal tract inta
Externí odkaz:
https://doaj.org/article/c093ba8175f84cbda8fecad55b6d5579
Publikováno v:
Cells, Vol 13, Iss 1, p 32 (2023)
Schizophrenia is a devastating neuropsychiatric disorder associated with the dysregulation of glutamate and dopamine neurotransmitter systems. The adenosine system is an important neuroregulatory system in the brain that modulates glutamate and dopam
Externí odkaz:
https://doaj.org/article/ae1650806d634066a95d9383bec7ac6a