Zobrazeno 1 - 10
of 24
pro vyhledávání: '"M, Nimgaonkar"'
Publikováno v:
Methods in molecular medicine. 7
Hematopoietic stem cells (HSC) provide for contmuous replenishment of the entire immune and hematopoietic systems, and also replenish themselves in a process termed self-renewal (1).The HSCs can be enriched from hematopoietic tissues using MAbs that
Autor:
M. Nimgaonkar, Alfred B. Bahnson, Bora E. Baysal, James T. Dunigan, R W Atchison, John A. Barranger, Edward D. Ball, T. Mohney
Publikováno v:
Journal of Virological Methods. 54:131-143
Centrifugation has been used for many years to enhance infection of cultured cells with a variety of different types of viruses, but it has only recently been demonstrated to be effective for retroviruses (Ho et al. (1993) J. Leukocyte Biol. 53, 208-
Hematopoietic stem cells (HSC) provide for contmuous replenishment of the entire immune and hematopoietic systems, and also replenish themselves in a process termed self-renewal (1).The HSCs can be enriched from hematopoietic tissues using MAbs that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08e9fd31fe9a0c694dbb801f00fa2c3c
https://doi.org/10.1385/0-89603-484-4:249
https://doi.org/10.1385/0-89603-484-4:249
Autor:
J. Lancia, Edward D. Ball, Nobuaki Takiyama, V. Bansal, William P. Swaney, M. Nimgaonkar, M. Beeler, T. Mohney, Alfred B. Bahnson, Mannion-Henderson J, John A. Barranger, M. Eljanne, A. Kemp, James T. Dunigan, Erin Rice, S. Schierer‐Fochler, J. Mierski, S. Lucot
Publikováno v:
Stem Cell Biology and Gene Therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::defb252e7d0fceacaa5060bc54d199d3
https://doi.org/10.1002/0471223956.ch13
https://doi.org/10.1002/0471223956.ch13
Publikováno v:
Journal of hematotherapy. 5(1)
Autologous bone marrow transplantation (ABMT) for acute myeloid leukemia (AML) in first complete remission (CR) results in a prolonged disease-free survival (DFS) of 34%-57%. Relapse of the underlying disease is the major cause for failure of ABMT. R
Autor:
J, Mannion-Henderson, A, Kemp, T, Mohney, M, Nimgaonkar, J, Lancia, M T, Beeler, J, Mierski, A B, Bahnson, E D, Ball, J A, Barranger
Publikováno v:
Experimental hematology. 23(14)
Obtaining efficient transfer of a normal gene and its sustained expression in self-renewing hematopoietic stem cell populations is a central concern for gene therapy initiatives. Potentially, 10(8) to 10(9) CD34+ enriched cells per patient will be re
Autor:
M, Nimgaonkar, J, Mierski, M, Beeler, A, Kemp, J, Lancia, J, Mannion-Henderson, T, Mohney, A, Bahnson, E, Rice, E D, Ball
Publikováno v:
Experimental hematology. 23(14)
As clinical trials for gene therapy in Gaucher disease (GD) begin, questions regarding the biology of the hematopoietic stem cell in this disease remain unanswered. This study demonstrates the ability to mobilize and collect CD34+ cells in three pati
Autor:
M, Nimgaonkar, A, Bahnson, A, Kemp, J, Lancia, J, Mannion-Henderson, S, Boggs, T, Mohney, B, Baysal, J, Dunigan, J A, Barranger
Publikováno v:
Leukemia. 9
Gaucher disease (GD), one of the most common inherited metabolic disorders, is an excellent candidate for gene therapy using hematopoietic stem cells as targets. Animal models have demonstrated the feasibility of introducing the human glucocerebrosid
Autor:
A B, Bahnson, M, Nimgaonkar, Y, Fei, S S, Boggs, P D, Robbins, T, Ohashi, J, Dunigan, J, Li, E D, Ball, J A, Barranger
Publikováno v:
Gene therapy. 1(3)
One promising strategy for gene therapy of Gaucher disease involves ex vivo retroviral transduction of autologous hematopoietic stem cells. Studies in small animals have demonstrated that this approach provides a life-long supply of the glucocerebros
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