Zobrazeno 1 - 10
of 258
pro vyhledávání: '"M, Nabholz"'
Publikováno v:
Label-free Biomedical Imaging and Sensing (LBIS) 2023.
A 1000-fold purification of human T-cell growth factor (TCGF) was achieved starting from supernatants of human spleen cells stimulated with phytohaemagglutinin (PHA) in culture medium containing 0.5% serum. The purification scheme involved precipitat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1838cbddbb119ae57521b9afa97bfb36
https://doi.org/10.1016/0022-1759(82)90236-8
https://doi.org/10.1016/0022-1759(82)90236-8
Autor:
M. Nabholz, M Cianfriglia, H Pohlit, Oreste Acuto, Andreas Conzelmann, Werner Haas, H von Boehmer, H R McDonald, Judy Johnson
Following the demonstration that hybrids between normal B-lymphocytes and myeloma cell lines continue to secrete antibodies with the same specificity as those produced by the parental B-cells1, many groups have tried to use this approach to obtain ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a886f40df4d0795ec2fa86a869ce2d20
https://ora.ox.ac.uk/objects/uuid:84d2ea3d-55cc-48c3-9712-a63f401c7fd3
https://ora.ox.ac.uk/objects/uuid:84d2ea3d-55cc-48c3-9712-a63f401c7fd3
Publikováno v:
International Journal of Cancer. 53:161-177
Publikováno v:
Genetica. 83:51-60
In order to improve the methods for the cytogenetic analysis of small rodents with regard to metaphase number, quality of chromosome resolution and duration of cultivation, a short-term culture technique from spleen cells, based on the capacity of Co
Publikováno v:
The Journal of Immunology. 145:3340-3347
We have analyzed the mechanisms by which IL-1, IL-2, and TNF regulate expression of IL-2R alpha chain in a rodent T cell line. All three cytokines induce detectable IL-2R alpha mRNA by themselves, but there is strong synergy between IL-1 or TNF, on t
Publikováno v:
The EMBO Journal. 9:929-937
We have analysed the enhancer activity and the interleukin 1 (IL1) responsiveness of individual motifs of the SV40 enhancer in an immature rodent T cell line, PC60. Transient transfection assays showed that tetramers of GT-I plus GT-IIC motifs, the T
Autor:
A L, Ducrest, M, Amacker, Y D, Mathieu, A P, Cuthbert, D A, Trott, R F, Newbold, M, Nabholz, J, Lingner
Publikováno v:
Cancer research. 61(20)
Telomerase is required for the complete replication of chromosomal ends. In tumors, the human telomerase reverse transcriptase subunit (hTERT) is up-regulated, thereby removing a critical barrier for unlimited cell proliferation. To understand more a
Publikováno v:
The Journal of biological chemistry. 276(9)
STAT transcription factors are expressed in many cell types and bind to similar sequences. However, different STAT gene knock-outs show very distinct phenotypes. To determine whether differences between the binding specificities of STAT proteins acco
Autor:
P, Sperisen, S M, Wang, E, Soldaini, M, Pla, C, Rusterholz, P, Bucher, P, Corthésy, P, Reichenbach, M, Nabholz
Publikováno v:
The Journal of biological chemistry. 270(18)
We have shown that interleukin-1 (IL-1) and IL-2 control IL-2 receptor alpha (IL-2R alpha) gene transcription in CD4-CD8- murine T lymphocyte precursors. Here we map the cis-acting elements that mediate interleukin responsiveness of the mouse IL-2R a