Zobrazeno 1 - 10
of 151
pro vyhledávání: '"M, Mersel"'
Autor:
D. Bochelen, Monika Adamczyk, F. Hor, Keith Langley, M. Mersel, Alexandre Kupferberg, Guy Vincendon
Publikováno v:
Journal of Neuroscience Research. 62:99-111
We have shown previously that 7beta-hydroxycholesterol (7betaOHCH) and 7beta-hydroxycholesteryl-3-oleate (7betaOHCH- 3-OL) are potent inhibitors of lesion-induced astrogliosis in the rat cortex or spinal cord; these substances reduce reactive astrocy
Autor:
Guy Vincendon, M. Mersel, Anant N. Malviya, Pascal Köppler, Jacques Vignon, Jean-Paul Humbert
Publikováno v:
Biochemistry. 35:5481-5487
Inositol 1,3,4,5-tetrakisphosphate (InsP4) mediates nuclear calcium signalling [Koppler P., Matter, N., Malviya A.N. (1993) J. Biol. Chem. 268, 26248-26252], and a distinct high affinity InsP4 binding site is identified with rat liver nuclei [Koppler
Autor:
A Legrand, N.-U. Rajaofetra, Alain Privat, M Giménez y Ribotta, Gérard Alonso, Françoise Sandillon, M. Mersel, C Morin-Richaud, D. Bochelen
Publikováno v:
Journal of Neuroscience Research. 41:79-95
In the present study, following previous experience with electrolytic lesion of the rat brain, and subsequent reduction of reactive gliosis with 7 beta-hydroxycholesterol derivatives (Bochelen et al.: Neuroscience 51:827-834, 1992), we have performed
Publikováno v:
Neuroscience. 51:827-834
Electrolytic lesions performed in brain cortex of six-day-old or adult rats resulted in the appearance of many reactive astrocytes around the injury site after a postoperative delay of eight days. They were revealed by immunohistochemistry using anti
Autor:
Patrick Behr, Paul-Francis Urban, M. Mersel, Laurence Schellenbaum, Claude Leray, Guy Vincendon, Alexandre Kupferberg
Publikováno v:
FEBS Letters. 313:151-154
Incubation of spontaneous transformed cells derived from astrocyte primary cultures with 30 microM 7 beta-hydroxycholesterol (7 beta-OH-CH) which is lethal to the cells or with 150 microM isoproterenol reduces the intracellular level of cAMP (4- and
Publikováno v:
Pigment cell research. 13(3)
The effects of calcium D-pantetheine-S-sulfonate (PaSSO3Ca) on human pigmentation were examined by in vitro assays using two types of human melanocytes: normal adult melanocytes (HNM) and M4Be melanoma cells. The compound, when added to a culture med
Publikováno v:
Journal of neuroscience research. 53(1)
We previously demonstrated that oxysterols inhibit the growth of experimental glioblastoma induced in the rat brain cortex. Mechanism of action of these compounds remains obscure. In this study, we investigated the effect of 7β-hydroxycholesterol (7
Publikováno v:
Neuroscience letters. 209(1)
The solubilisation of the γ-hydroxybutyrate (GHB) receptors from rat brain membranes was undertaken as the first step for their molecular characterisation and purification. Treatment of crude brain membranes with high concentrations of NaCl and Trit
Publikováno v:
Journal of neurochemistry. 65(5)
We have reported previously that oxysterols inhibit astrogliosis and intracranial glioblastoma growth. To elucidate the mechanism of action of these molecules in vivo, we have investigated their effect on the cholesterol biosynthesis in the injured b
Autor:
M, Giménez y Ribotta, N, Rajaofetra, C, Morin-Richaud, G, Alonso, D, Bochelen, F, Sandillon, A, Legrand, M, Mersel, A, Privat
Publikováno v:
Journal of neuroscience research. 41(1)
In the present study, following previous experience with electrolytic lesion of the rat brain, and subsequent reduction of reactive gliosis with 7 beta-hydroxycholesterol derivatives (Bochelen et al.: Neuroscience 51:827-834, 1992), we have performed