Zobrazeno 1 - 10
of 2 156
pro vyhledávání: '"M, McNamara"'
Autor:
Dennis M. McNamara, Leslie T. Cooper, Yaron Arbel, Arvind Bhimaraj, Edimar Bocchi, Matthias G. Friedrich, Matthieu Kerneis, Peter Liu, Andrea B. Parker, Eldon R. Smith, W. H. Wilson Tang, Guillermo Torre‐Amione, Carsten Tschöpe, ARCHER Study Group
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 3416-3424 (2024)
Abstract Aims Acute myocarditis, although a rare disease, can be associated with sudden cardiac death or the need for transplantation in both children and young adults. To date, there is no definitive evidence to support the routine use of immunosupp
Externí odkaz:
https://doaj.org/article/31deb9cc7adf4749a23a3d02a5ba63f7
Autor:
Jia Li, Alan J. Simmons, Caroline V. Hawkins, Sophie Chiron, Marisol A. Ramirez-Solano, Naila Tasneem, Harsimran Kaur, Yanwen Xu, Frank Revetta, Paige N. Vega, Shunxing Bao, Can Cui, Regina N. Tyree, Larry W. Raber, Anna N. Conner, Jennifer M. Pilat, Justin Jacobse, Kara M. McNamara, Margaret M. Allaman, Gabriella A. Raffa, Alain P. Gobert, Mohammad Asim, Jeremy A. Goettel, Yash A. Choksi, Dawn B. Beaulieu, Robin L. Dalal, Sara N. Horst, Baldeep S. Pabla, Yuankai Huo, Bennett A. Landman, Joseph T. Roland, Elizabeth A. Scoville, David A. Schwartz, M. Kay Washington, Yu Shyr, Keith T. Wilson, Lori A. Coburn, Ken S. Lau, Qi Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Crohn’s disease (CD) is a complex chronic inflammatory disorder with both gastrointestinal and extra-intestinal manifestations associated immune dysregulation. Analyzing 202,359 cells from 170 specimens across 83 patients, we identify a di
Externí odkaz:
https://doaj.org/article/0ba81d63e38741479e8c66302f19cf18
Autor:
Agnes Koczo, Deeksha Acharya, Benay Ozbay, Rami Alharethi, Michael M. Givertz, Uri Elkayam, Erik B. Schelbert, Dennis M. McNamara, Timothy C. Wong
Publikováno v:
American Heart Journal Plus, Vol 48, Iss , Pp 100484- (2024)
Background: Peripartum cardiomyopathy (PPCM) is associated with significant morbidity and mortality. Recent studies show recovery of left ventricular ejection fraction (LVEF) can still be associated with longitudinal adverse clinical outcomes. Cardia
Externí odkaz:
https://doaj.org/article/df87d94d213a4c8d89fa9fe59060c612
Autor:
Yvonne L. Latour, Kara M. McNamara, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Mohammad Asim, Kamery J. Williams, Caroline V. Hawkins, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The intestinal immune response is crucial in maintaining a healthy gut, but the enhanced migration of macrophages in response to pathogens is a major contributor to disease pathogenesis. Integrins are ubiquitously expressed cellular receptor
Externí odkaz:
https://doaj.org/article/fb0bf8276c3646598c802c501115e29e
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114043- (2024)
Summary: Bone is highly susceptible to cancer metastasis, and both tumor and bone cells enable tumor invasion through a “vicious cycle” of biochemical signaling. Tumor metastasis into bone also alters biophysical cues to both tumor and bone cells
Externí odkaz:
https://doaj.org/article/be86c3ad2f6a474f92ba5cc633e4825d
Autor:
Md Asad Rahman, Chunhui Cai, Na Bo, Dennis M. McNamara, Ying Ding, Gregory F. Cooper, Xinghua Lu, Jinling Liu
Publikováno v:
BMC Genomics, Vol 23, Iss S5, Pp 1-15 (2023)
Abstract Background Genomic variants of the disease are often discovered nowadays through population-based genome-wide association studies (GWAS). Identifying genomic variations potentially underlying a phenotype, such as hypertension, in an individu
Externí odkaz:
https://doaj.org/article/a813ca4909ff442692ff81de67d41f10
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Optogenetic tools can provide fine spatial and temporal control over many biological processes. Yet the development of new light-switchable protein variants remains challenging, and the field still lacks general approaches to engineering or
Externí odkaz:
https://doaj.org/article/b4e2ac9c372d43eea2bd320ea8fbd09b
Autor:
Yvonne L. Latour, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Kamery J. Williams, Kara M. McNamara, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, Shilin Zhao, Alain P. Gobert, Keith T. Wilson
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTPathogenic enteric Escherichia coli present a significant burden to global health. Food-borne enteropathogenic E. coli (EPEC) and Shiga toxin-producing E. coli (STEC) utilize attaching and effacing (A/E) lesions and actin-dense pedestal forma
Externí odkaz:
https://doaj.org/article/f9ea48e1d73a40c2ba5b50cc0608468a
Autor:
Q. Chen, J. A. Mirrielees, S. Thanekar, N. A. Loeb, R. M. Kirpes, L. M. Upchurch, A. J. Barget, N. N. Lata, A. R. W. Raso, S. M. McNamara, S. China, P. K. Quinn, A. P. Ault, A. Kennedy, P. B. Shepson, J. D. Fuentes, K. A. Pratt
Publikováno v:
Atmospheric Chemistry and Physics, Vol 22, Pp 15263-15285 (2022)
Sea salt aerosols play an important role in the radiation budget and atmospheric composition over the Arctic, where the climate is rapidly changing. Previous observational studies have shown that Arctic sea ice leads are an important source of sea sa
Externí odkaz:
https://doaj.org/article/332a52e36d664e2784f5bcf0364248e7
Autor:
K. D. Kulju, S. M. McNamara, Q. Chen, H. S. Kenagy, J. Edebeli, J. D. Fuentes, S. B. Bertman, K. A. Pratt
Publikováno v:
Atmospheric Chemistry and Physics, Vol 22, Pp 2553-2568 (2022)
The atmospheric multiphase reaction of dinitrogen pentoxide (N2O5) with chloride-containing aerosol particles produces nitryl chloride (ClNO2), which has been observed across the globe. The photolysis of ClNO2 produces chlorine radicals and nitrogen
Externí odkaz:
https://doaj.org/article/d84e89df4e3a4616ac03be353d33c881