Zobrazeno 1 - 10
of 217
pro vyhledávání: '"M, Maral Mouradian"'
Autor:
Ahmad Almelegy, Srujanesh Gunda, Steven Buyske, Marc Rosenbaum, Sepehr Sani, Mitra Afshari, Leo V. Metman, Christopher G. Goetz, Deborah Hall, M. Maral Mouradian, Gian Pal
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 4, Pp 899-904 (2024)
Abstract Objective Mutations in the glucocerebrosidase (GBA1) gene and subthalamic nucleus deep brain stimulation (STN‐DBS) are independently associated with cognitive dysfunction in persons with Parkinson's disease (PwP). We hypothesized that PwP
Externí odkaz:
https://doaj.org/article/3ca10e22374e402a83dbc53cebc9f07c
Autor:
Robert C. Griggs, M. Maral Mouradian
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00385- (2024)
Externí odkaz:
https://doaj.org/article/5a0101ea07cf453ca53bc231af2bcedc
Autor:
Tae Hwan Shin, Balachandran Manavalan, Da Yeon Lee, Shaherin Basith, Chan Seo, Man Jeong Paik, Sang-Wook Kim, Haewoon Seo, Ju Yeon Lee, Jin Young Kim, A Young Kim, Jee Min Chung, Eun Joo Baik, Seong Ho Kang, Dong-Kug Choi, Yup Kang, M. Maral Mouradian, Gwang Lee
Publikováno v:
Particle and Fibre Toxicology, Vol 18, Iss 1, Pp 1-24 (2021)
Abstract Background Nanoparticles have been utilized in brain research and therapeutics, including imaging, diagnosis, and drug delivery, owing to their versatile properties compared to bulk materials. However, exposure to nanoparticles leads to thei
Externí odkaz:
https://doaj.org/article/5a3f65fab7ff4f3ea7bfc98a0d28a485
Autor:
Yanying Huo, Akshada Sawant, Yongmei Tan, Amar H Mahdi, Tao Li, Hui Ma, Vrushank Bhatt, Run Yan, Jake Coleman, Cheryl F Dreyfus, Jessie Yanxiang Guo, M Maral Mouradian, Eileen White, Bing Xia
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010138 (2022)
The PALB2 tumor suppressor plays key roles in DNA repair and has been implicated in redox homeostasis. Autophagy maintains mitochondrial quality, mitigates oxidative stress and suppresses neurodegeneration. Here we show that Palb2 deletion in the mou
Externí odkaz:
https://doaj.org/article/a14fbad6b37441618cc40a94f6c51743
Autor:
Lauren B. Reoma, Ania Busza, M. Maral Mouradian, Petra Kaufmann, Erika F. Augustine, Samuel Frank, Thomas P. Sutula, Andrew J. Cole, Heather D. Fitter, William Meurer, Avindra Nath, Robert C. Griggs
Publikováno v:
Annals of Neurology. 93:427-430
The subspecialty of Experimental Neurotherapeutics trains neurologists in discovering and developing new treatments for neurologic diseases. Based on development of exciting new treatments for genetic and inflammatory diseases, we predict that there
Autor:
Stephanie E. Oh, Hye-Jin Park, Liqiang He, Catherine Skibiel, Eunsung Junn, M. Maral Mouradian
Publikováno v:
Redox Biology, Vol 19, Iss , Pp 62-73 (2018)
DJ-1 is a highly conserved protein that protects neurons against oxidative stress and whose loss of function mutations are linked to recessively inherited Parkinson's disease (PD). While a number of signaling pathways have been shown to be regulated
Externí odkaz:
https://doaj.org/article/a6deec5a17154d2bbe465d90849ce83a
Autor:
Stephanie E. Oh, M. Maral Mouradian
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 211-217 (2018)
DJ-1 is a highly conserved multifunctional protein linked to both neurodegeneration and neoplasia. Among its various activities is an antioxidant property leading to cytoprotection under oxidative stress conditions. This is associated with the abilit
Externí odkaz:
https://doaj.org/article/3a4dff679c5c4cb8883c9091c7373af3
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 8, Pp 1560-1561 (2021)
Externí odkaz:
https://doaj.org/article/f2b410965de8450e95ece5a997c9d601
Autor:
Gian Pal, Laura Bennett, Jason Roy, Abner Nyandege, M. Maral Mouradian, Tobias Gerhard, Daniel Horton
Publikováno v:
Monday, April 24.
Autor:
Gian Pal, Graziella Mangone, Emily J. Hill, Bichun Ouyang, Yuanqing Liu, Vanessa Lythe, Debra Ehrlich, Rachel Saunders‐Pullman, Vicki Shanker, Susan Bressman, Roy N. Alcalay, Priscilla Garcia, Karen S. Marder, Jan Aasly, M. Maral Mouradian, Samantha Link, Marc Rosenbaum, Sharlet Anderson, Bryan Bernard, Robert Wilson, Glenn Stebbins, William C. Nichols, Marie‐Laure Welter, Sepehr Sani, Mitra Afshari, Leo Verhagen, Rob M.A. Bie, Tom Foltynie, Deborah Hall, Jean‐Christophe Corvol, Christopher G. Goetz
Publikováno v:
Annals of neurology, 91(3), 424-435. John Wiley and Sons Inc.
Objective: This study was undertaken to compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and noncarriers with and without subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson disease. Methods: Cl