Zobrazeno 1 - 10
of 55
pro vyhledávání: '"M, Mannesse"'
Autor:
H. M. Verheij, Henri A. M. Pepermans, M. L. M. Mannesse, A. Groenewegen, M. R. Egmond, Cornelis W. Hilbers, Jeanine J. Prompers, B. Van Noorloos
Publikováno v:
Biochemistry, 38(19), 5982-5994. American Chemical Society
The backbone dynamics of Fusarium solani pisi cutinase in complex with a phosphonate inhibitor has been studied by a variety of nuclear magnetic resonance experiments to probe internal motions on different time scales. The results have been compared
Autor:
M. L. M. Mannesse, Hubertus M. Verheij, G.H. de Haas, Maarten R. Egmond, Christian Cambillau, Sonia Longhi, E. Knoops-Mouthuy
Publikováno v:
Protein Science. 6:275-286
Cutinase from Fusarium solani is a lipolytic enzyme that hydrolyses triglycerides efficiently. All the inhibited forms of lipolytic enzymes described so far are based on the use of small organophosphate and organophosphonate inhibitors, which bear li
Autor:
G.H. de Haas, Maarten Robert Egmond, H. T. W. M. van der Hijden, A.T. Slotboom, M. L. M. Mannesse, J.-W.P. Boots, R. Dijkman, Hubertus M. Verheij
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1259:56-64
1,2-Dioctylcarbamoylglycero-3-O-p-nitrophenyl alkylphosphonates, with alkyl being methyl or octyl, were synthesised and tested as irreversible inhibitors of cutinase from Fusarium solani pisi and Staphylococcus hyicus lipase. Rapid inactivation of th
Autor:
G.H. de Haas, J. De Vlieg, Bart C. Koops, H. T. W. M. Van Der Hijden, Maarten Robert Egmond, Hubertus M. Verheij, Ruud C. Cox, M. L. M. Mannesse
Publikováno v:
Biochemistry. 34:6400-6407
Triglyceride analogues were synthesized in which one of the primary acyl ester functions has been replaced by an alkyl group and the secondary acyl ester bond has been replaced by an acyl amino bond. The chain length at either position was varied, an
Autor:
J. Zuidema, M. Mannesse
Publikováno v:
Engineering Fracture Mechanics. 40:105-117
Fatigue tests with constant Δk and R were performed on specimens of 2024-T351 Al alloy. Fatigue crack growth starts in the tensile mode, but shear lips soon develop if Δk is high enough. Three properties of these shear lips are described: the trans
Autor:
Hubertus M. Verheij, Gerard H. de Haas, Maurice L. M. Mannesse, Dietmar A. Lang, Bauke W. Dijkstra
Publikováno v:
European Journal of Biochemistry, 254(2), 333-340. Blackwell Publishing Ltd
To investigate the enantioselectivity of Pseudomonas cepacia lipase, inhibition studies were performed with S(c)-and R(c)-(R(p),S(p))-1,2-dialkylcarbamoylglycero-3-O-p-nitrophenyl alkylphosphonates of different alkyl chain lengths. P. cepacia lipase
Autor:
G.H. de Haas, Hubertus M. Verheij, Maarten Robert Egmond, H. T. W. M. van der Hijden, M. L. M. Mannesse
Publikováno v:
Biochemical Society transactions. 25(1)
Autor:
S, Longhi, M, Mannesse, H M, Verheij, G H, De Haas, M, Egmond, E, Knoops-Mouthuy, C, Cambillau
Publikováno v:
Protein science : a publication of the Protein Society. 6(2)
Cutinase from Fusarium solani is a lipolytic enzyme that hydrolyses triglycerides efficiently. All the inhibited forms of lipolytic enzymes described so far are based on the use of small organophosphate and organophosphonate inhibitors, which bear li
Publikováno v:
Development (Cambridge, England). 110(2)
Recently, we presented evidence that protein kinase C (PKC) is involved in mediating the endogenous signals that induce competent Xenopus ectoderm to differentiate to neural tissue. We report here that PKC is already strongly activated in neural-indu
Autor:
J. Zuidema, M. Mannesse
Publikováno v:
Engineering Fracture Mechanics. 34:445-456
Constant Δ K tests on specimens of 2024-T351 A1 alloy have been performed. Fatigue crack growth starts in the tensile mode, but then shear lips are developed if ΔK is high enough. The crack growth rate of the unstable tensile mode at the start of t