Zobrazeno 1 - 10
of 80
pro vyhledávání: '"M, Maler"'
Autor:
Philipp Spitzer, Roland Lang, Timo J. Oberstein, Piotr Lewczuk, Natalia Ermann, Hagen B. Huttner, Ilias Masouris, Johannes Kornhuber, Uwe Ködel, Juan M. Maler
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
A reduced concentration of Aβ1−42 in CSF is one of the established biomarkers of Alzheimer's disease. Reduced CSF concentrations of Aβ1−42 have also been shown in multiple sclerosis, viral encephalitis and bacterial meningitis. As neuroinflamma
Externí odkaz:
https://doaj.org/article/e171ea72a63647559dd777a9a9272aed
Autor:
Arkady M. Maler
Publikováno v:
Almanac “Essays on Conservatism”. 29:131-138
The article shows the development of the concept of personality in the history of philosophy as the key value of European civilization. The main problem of understanding personality is that this concept arose exclusively in the context of the formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce12b688979bbf62e0a3cac652135809
https://doi.org/10.24030/24092517-2019-0-3-131-138
https://doi.org/10.24030/24092517-2019-0-3-131-138
Autor:
M. Maler, J. Kornhuber, P. Lewczuk, M. Bibl, H. Esselmann, Hans-Wolfgang Klafki, Jens Wiltfang
Publikováno v:
Nervenheilkunde. 26:861-866
ZusammenfassungDie vorliegende Arbeit soll eine Übersicht über innovative diagnostische Ansätze der Neurochemischen Demenzdiagnostik (NDD) geben. Eine verbesserte Früh- und Differenzialdiagnostik demenzieller Erkrankungen ist unter dem Aspekt sic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0882ad5e3a8f35532b0873c2e7f0bac0
https://doi.org/10.1055/s-0038-1626937
https://doi.org/10.1055/s-0038-1626937
Autor:
M. Maler, Jens Wiltfang, Hans-Wolfgang Klafki, H. Esselmann, M. Bibl, J. Kornhuber, P. Lewczuk
Publikováno v:
Nervenheilkunde. 26:853-860
ZusammenfassungDie vorliegende Arbeit soll eine Übersicht über das sich schnell entwickelnde Gebiet der Neurochemischen Demenzdiagnostik (NDD) geben, wobei der Schwerpunkt auf Anwendungen liegen soll, die zwischenzeitlich bereits Eingang in die Rou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d9d50e808bcc2d752b2877474a93473
https://doi.org/10.1055/s-0038-1626936
https://doi.org/10.1055/s-0038-1626936
Publikováno v:
Fortschritte der Neurologie · Psychiatrie. 71:36-44
Glutamate is the neurotransmitter at the majority of excitatory synapses in the mammalian CNS. It has been proposed that neurotoxicity linked to chronic alcoholism is mediated primarily by activation of glutamate N-methyl-D-aspartate (NMDA) receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1a7075445981c73b11c96586bf445f
https://doi.org/10.1055/s-2003-40504
https://doi.org/10.1055/s-2003-40504
Autor:
T. Dyrks, S. Paul, Markus Otto, Hans-Wolfgang Klafki, E. Rüther, M. Maler, Mirko Bibl, Bernhard Schmidt, Jens Wiltfang, Hermann Esselmann, M. Bienert, M. Beyermann, Alexandr F Smirnov, Johannes Kornhuber
Publikováno v:
Journal of Neurochemistry. 81:481-496
Human lumbar CSF patterns of Aβ peptides were analysed by urea-based β-amyloid sodium dodecyl sulphate polyacrylamide gel electrophoresis with western immunoblot (Aβ-SDS–PAGE/immunoblot). A highly conserved pattern of carboxyterminally truncated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce073d2cd44dd03e55429a5a8d10f44a
https://doi.org/10.1046/j.1471-4159.2002.00818.x
https://doi.org/10.1046/j.1471-4159.2002.00818.x
Publikováno v:
Fortschritte der Neurologie · Psychiatrie. 69:56-61
Glutamate is the most abundant amino acid in the brain, where it plays an important role as a well-established major excitatory neurotransmitter in the central nervous system. It has been suggested that reduced glutamate neurotransmission may be invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a13e3ece116c867cdd0453b99a03617
https://doi.org/10.1055/s-2001-16531
https://doi.org/10.1055/s-2001-16531
Publikováno v:
Journal of Neural Transmission. 106:857-867
The spectrum of action of flupirtine includes analgesia, muscle relaxation and neuroprotection. N-methyl-D-aspartate (NMDA) receptor antagonism has been discussed as a possible mechanism of action of this compound with little direct evidence. The obj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::288f09c2a1016f4a2caf69682736dc04
https://doi.org/10.1007/s007020050206
https://doi.org/10.1007/s007020050206
Publikováno v:
Fortschritte der Neurologie · Psychiatrie. 67:466-475
The spectrum of action of flupirtine includes analgesic, muscle-relaxant and neuroprotective properties. The substance's mechanism of action has yet to be fully explained. Over the past few years, however, evidence has accumulated that flupirtine int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ac134f0213b5dc0524b7f8ba8430f7
https://doi.org/10.1055/s-2007-994997
https://doi.org/10.1055/s-2007-994997
Autor:
Martin Herrmann, Piotr Lewczuk, Jens Wiltfang, Johannes Kornhuber, Philipp Spitzer, J. M. Maler
Publikováno v:
Molecular Psychiatry. 11:1113-1115
Hematopoietic stem cells contribute to mammalian brain tissue regeneration by transdifferentiation processes. We found decreased counts of circulating CD34+ cells in early Alzheimer's dementia (AD; P = 0.01), which significantly correlated with age (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494ee98e40b0f6c98a7d81a91f0fb395
https://doi.org/10.1038/sj.mp.4001913
https://doi.org/10.1038/sj.mp.4001913