Zobrazeno 1 - 10
of 2 604
pro vyhledávání: '"M, Magnani"'
Autor:
Joanna Zikos, Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko, Ala M. Shaqra, Celia A. Schiffer, Koen K. A. Van Rompay, Jonah B. Sacha, Diogo M. Magnani
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Prenatal administration of monoclonal antibodies (mAbs) is a strategy that could be exploited to prevent viral infections during pregnancy and early life. To reach protective levels in fetuses, mAbs must be transported across the placenta, a selectiv
Externí odkaz:
https://doaj.org/article/c3903556c3ab42faabeedc9cf418281c
Publikováno v:
European Psychiatry, Vol 67, Pp S695-S695 (2024)
Introduction The single-injection start regimen for aripiprazole once-monthly 400 mg (AOM 400) in patients with schizofrenia requires a single intramuscular injection in the gluteal or deltoid site and 14 days of concurrent oral therapy. Based on a
Externí odkaz:
https://doaj.org/article/34fc78113d45455da32e31f702c04693
Autor:
Matthew S. Sutton, Allison N. Bucsan, Chelsea C. Lehman, Megha Kamath, Supriya Pokkali, Diogo M. Magnani, Robert Seder, Patricia A. Darrah, Mario Roederer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Understanding the immunological control of pathogens requires a detailed evaluation of the mechanistic contributions of individual cell types within the immune system. While knockout mouse models that lack certain cell types have been used to help de
Externí odkaz:
https://doaj.org/article/95faee24c36f4d139c41cce54445ee40
Autor:
Sedem Dankwa, Christina Kosman, Maria Dennis, Elena E Giorgi, Kenneth Vuong, Ioanna Pahountis, Ashley Garza, Christian Binuya, Janice McCarthy, Bryan T Mayer, Julia T Ngo, Chiamaka A Enemuo, Diane G Carnathan, Sherry Stanfield-Oakley, Stella J Berendam, Carolyn Weinbaum, Kathleen Engelman, Diogo M Magnani, Cliburn Chan, Guido Ferrari, Guido Silvestri, Rama R Amara, Ann Chahroudi, Sallie R Permar, Genevieve G Fouda, Ria Goswami
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0312411 (2024)
To eliminate vertical HIV transmission and achieve therapy-free viral suppression among children living with HIV, novel strategies beyond antiretroviral therapy (ART) are necessary. Our group previously identified a triple broadly neutralizing antibo
Externí odkaz:
https://doaj.org/article/67249a617a5941c98087a2a5528cf93f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Stable walking relies critically on motor responses to signals of head motion provided by the vestibular system, which are phase-dependent and modulated differently within each muscle. It is unclear, however, whether these vestibular contrib
Externí odkaz:
https://doaj.org/article/dcd87e350a264bfaab6b969dd9dd2ab3
Autor:
Xiao L. Chang, Gabriela M. Webb, Helen L. Wu, Justin M. Greene, Shaheed Abdulhaqq, Katherine B. Bateman, Jason S. Reed, Cleiton Pessoa, Whitney C. Weber, Nicholas Maier, Glen M. Chew, Roxanne M. Gilbride, Lina Gao, Rebecca Agnor, Travis Giobbi, Jeffrey Torgerson, Don Siess, Nicole Burnett, Miranda Fischer, Oriene Shiel, Cassandra Moats, Bruce Patterson, Kush Dhody, Scott Kelly, Nader Pourhassan, Diogo M. Magnani, Jeremy Smedley, Benjamin N. Bimber, Nancy L. Haigwood, Scott G. Hansen, Timothy R. Brown, Lishomwa C. Ndhlovu, Jonah B. Sacha
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
CCR5 is a co-receptor for many transmitted HIV strains. Here, the authors show that biweekly injection of the CCR5-specific antibody Leronlimab protects rhesus macaques against infection following repeated intrarectal challenges of a CCR5-tropic SHIV
Externí odkaz:
https://doaj.org/article/e057d02dc1bf44278b9075dfe29c62e7
Autor:
Cássia G. T. Silveira, Diogo M. Magnani, Priscilla R. Costa, Vivian I. Avelino-Silva, Michael J. Ricciardi, Maria do Carmo S. T. Timenetsky, Raphaella Goulart, Carolina A. Correia, Mariana P. Marmorato, Lilian Ferrari, Zelinda B. Nakagawa, Claudia Tomiyama, Helena Tomiyama, Jorge Kalil, Ricardo Palacios, Alexander R. Precioso, David I. Watkins, Esper G. Kallás
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An effective vaccine against the dengue virus (DENV) should induce a balanced, long-lasting antibody (Ab) response against all four viral serotypes. The burst of plasmablasts in the peripheral blood after vaccination may reflect enriched vaccine-spec
Externí odkaz:
https://doaj.org/article/f79ebe28522144e8bb445ccb7d47e353
Autor:
Nuria Pedreño-Lopez, Christine M. Dang, Brandon C. Rosen, Michael J. Ricciardi, Varian K. Bailey, Martin J. Gutman, Lucas Gonzalez-Nieto, Matthias G. Pauthner, Khoa Le, Ge Song, Raiees Andrabi, Kim L. Weisgrau, Nicholas Pomplun, José M. Martinez-Navio, Sebastian P. Fuchs, Jens Wrammert, Eva G. Rakasz, Jeffrey D. Lifson, Mauricio A. Martins, Dennis R. Burton, David I. Watkins, Diogo M. Magnani
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 16, Iss , Pp 225-237 (2020)
Structural characterization of the HIV-1 Envelope (Env) glycoprotein has facilitated the development of Env probes to isolate HIV-specific monoclonal antibodies (mAbs). However, preclinical studies have largely evaluated these virus-specific mAbs aga
Externí odkaz:
https://doaj.org/article/583e2f5e1bdc4c94b11792ddc7103b3a
Autor:
Andrew R. Crowley, Nana Yaw Osei-Owusu, Gillian Dekkers, Wenda Gao, Manfred Wuhrer, Diogo M. Magnani, Keith A. Reimann, Seth H. Pincus, Gestur Vidarsson, Margaret E. Ackerman
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering e
Externí odkaz:
https://doaj.org/article/624dbe4963b94790af2f76bded8b1288
Autor:
Miriam Manook, Walter J. Flores, Robin Schmitz, Zachary Fitch, Janghoon Yoon, Yeeun Bae, Brian Shaw, Allan Kirk, Melissa Harnois, Sallie Permar, Alton B. Farris, Diogo M. Magnani, Jean Kwun, Stuart Knechtle
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundIn transplantation, plasmapheresis and IVIg provide the mainstay of treatment directed at reducing or removing circulating donor-specific antibody (DSA), yet both have limitations. We sought to test the efficacy of targeting the IgG recycli
Externí odkaz:
https://doaj.org/article/1f0e067ea29d456693bbacb7f1722d6b