Zobrazeno 1 - 10
of 976
pro vyhledávání: '"M, Lipton"'
Autor:
Alyssa L. Kennedy, Kasiani C. Myers, James Bowman, Christopher J. Gibson, Nicholas D. Camarda, Elissa Furutani, Gwen M. Muscato, Robert H. Klein, Kaitlyn Ballotti, Shanshan Liu, Chad E. Harris, Ashley Galvin, Maggie Malsch, David Dale, John M. Gansner, Taizo A. Nakano, Alison Bertuch, Adrianna Vlachos, Jeffrey M. Lipton, Paul Castillo, James Connelly, Jane Churpek, John R. Edwards, Nobuko Hijiya, Richard H. Ho, Inga Hofmann, James N. Huang, Siobán Keel, Adam Lamble, Bonnie W. Lau, Maxim Norkin, Elliot Stieglitz, Wendy Stock, Kelly Walkovich, Steffen Boettcher, Christian Brendel, Mark D. Fleming, Stella M. Davies, Edie A. Weller, Christopher Bahl, Scott L. Carter, Akiko Shimamura, R. Coleman Lindsley
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Understanding the molecular basis of leukaemia predisposition is essential for intervention. The authors here investigate germline genetic leukaemia predisposition by studying Shwachman-Diamond syndrome and report compensatory inactivating mutations
Externí odkaz:
https://doaj.org/article/911d91b30d4548af8f9e72d025592f4b
Autor:
Rameswari Chilamakuri, Danielle C. Rouse, Yang Yu, Abbas S. Kabir, Aaron Muth, Jianhua Yang, Jeffery M. Lipton, Saurabh Agarwal
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101272- (2022)
High-risk neuroblastoma (NB) represents a major clinical challenge in pediatric oncology due to relapse of metastatic, drug-resistant disease, and treatment-related toxicities. An analysis of 1235 primary NB patient dataset revealed significant incre
Externí odkaz:
https://doaj.org/article/876fff3a8ac947789e0b637412ec2d83
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 17801-17817 (2018)
Biomass-burning organic-aerosol (OA) emissions are known to exhibit semi-volatile behavior that impacts OA loading during plume transport. Because such semi-volatile behavior depends in part on OA composition, improved speciation of intermediate and
Externí odkaz:
https://doaj.org/article/021f7486d1334cb3a9710f508b082cae
Autor:
D. Matthew Gianferante, Marcin W. Wlodarski, Evangelia Atsidaftos, Lydie Da Costa, Polyxeni Delaporta, Jason E. Farrar, Frederick D. Goldman, Maryam Hussain, Antonis Kattamis, Thierry Leblanc, Jeffrey M. Lipton, Charlotte M. Niemeyer, Dagmar Pospisilova, Paola Quarello, Ugo Ramenghi, Vijay G. Sankaran, Adrianna Vlachos, Jana Volejnikova, Blanche P. Alter, Sharon A. Savage, Neelam Giri
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Diamond Blackfan anemia (DBA) is predominantly an autosomal dominant inherited red cell aplasia primarily caused by pathogenic germline variants in ribosomal protein genes. DBA due to pathogenic RPL35A variants has been associated with large 3q29 del
Externí odkaz:
https://doaj.org/article/6dcaa279444c45d49f67d28d56e40b5d
Publikováno v:
Cell Reports, Vol 24, Iss 10, Pp 2709-2722 (2018)
Summary: The proper assembly of neural circuits depends on the process of synaptogenesis, or the formation of synapses between partner neurons. Using the dopaminergic PDE neurons in C. elegans, we developed an in vivo system to study the earliest ste
Externí odkaz:
https://doaj.org/article/d5455ed65f9549039c516ff82cb6741a
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-15 (2018)
Abstract Erythropoiesis is a tightly-regulated and complex process originating in the bone marrow from a multipotent stem cell and terminating in a mature, enucleated erythrocyte. Altered red cell production can result from the direct impairment of m
Externí odkaz:
https://doaj.org/article/39bd3718db0848f48345348128bdc362
Publikováno v:
Frontiers in Systems Neuroscience, Vol 13 (2019)
Here, we review the neural circuit bases of habits, compulsions, and addictions, behaviors which are all characterized by relatively automatic action performance. We discuss relevant studies, primarily from the rodent literature, and describe how maj
Externí odkaz:
https://doaj.org/article/aa105ad093e948b4bd4bfb786086a90c
Autor:
Shinsuke Niwa, David M. Lipton, Manatsu Morikawa, Charles Zhao, Nobutaka Hirokawa, Hang Lu, Kang Shen
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2129-2141 (2016)
Kinesin motor proteins transport intracellular cargoes throughout cells by hydrolyzing ATP and moving along microtubule tracks. Intramolecular autoinhibitory interactions have been shown for several kinesins in vitro; however, the physiological signi
Externí odkaz:
https://doaj.org/article/54dfcd7cd3624f62b8129cd2abdf3e49
Autor:
Winfred C. Wang, Ashley Galvin, Maggie Malsch, Rabi Hanna, Kasiani C. Myers, Edie Weller, Leann Mount, Bonnie W Lau, Kelan Queenan, Robert B. Lorsbach, Taizo A. Nakano, Adrianna Vlachos, Shanshan Liu, Mark D. Fleming, Sarah K. Steltz, Stella M. Davies, Jordan Henry Larson, Sara Loveless, Akiko Shimamura, Elissa Furutani, Sioban Keel, Amy E. Geddis, John M. Gansner, Alison A. Bertuch, Jeffrey M. Lipton
Publikováno v:
Blood Advances
Key Points Severe bone marrow failure was primarily observed in early childhood in children with biallelic SBDS mutations.Absolute neutrophil counts were positively associated with age (P < .0001) in patients with biallelic SBDS mutations.
Visua
Visua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e781b5291a00cc8249c1831deb3cc9a
https://doi.org/10.1182/bloodadvances.2021005539
https://doi.org/10.1182/bloodadvances.2021005539
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