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of 5 235
pro vyhledávání: '"M, Lawn"'
Autor:
John F. Oram, Richard M. Lawn
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 8, Pp 1173-1179 (2001)
It is widely believed that HDL functions to transport cholesterol from peripheral cells to the liver by reverse cholesterol transport, a pathway that may protect against atherosclerosis by clearing excess cholesterol from arterial cells. A cellular A
Externí odkaz:
https://doaj.org/article/043540628582412fa786ed1b1c16156a
Autor:
Matthias Schneider, Joseph L. Witztum, Stephen G. Young, Erwin H. Ludwig, Elizabeth R. Miller, Sotirios Tsimikas, Linda K. Curtiss, Santica M. Marcovina, John M. Taylor, Richard M. Lawn, Thomas L. Innerarity, Robert E. Pitas
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 769-778 (2005)
Efforts to elucidate the role of lipoprotein [a] (Lp[a]) in atherogenesis have been hampered by the lack of an animal model with high plasma Lp[a] levels. We produced two lines of transgenic mice expressing apolipoprotein [a] (apo[a]) in the liver an
Externí odkaz:
https://doaj.org/article/c7cddf410c7d4802996d9f55cdd11fad
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 11, Pp 2039-2048 (2003)
Liver X receptor (LXR) ligands are currently being evaluated as potential therapeutic agents for the treatment of low HDL. The LXR ligand T0901317 elevates ATP binding cassette transporter A1 (ABCA1) and HDL levels in animal models and induces modera
Externí odkaz:
https://doaj.org/article/06e47c732d934c9789fa8c4449e3b9a6
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 12, Pp 2263-2267 (1994)
Elevated levels of apolipoprotein[a] (apo[a]) and apolipoprotein A-I (apoA-I) are associated, respectively, with increased and decreased atherosclerosis risk, in both humans and transgenic mice. To investigate the interactions of these two important
Externí odkaz:
https://doaj.org/article/e194990353ce4ec0a81302e5254efe18
Akademický článek
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Publikováno v:
QJM: An International Journal of Medicine. 110:735-739
Background The NICE guidelines for blood transfusion and the patient blood management recommendations state that a single unit of red cells should be the standard dose for patients with stable anaemia who are not bleeding. Studies have shown that cha
Autor:
Stephan Wolf, J. Uprichard, M. Lawn, K. Feane, K. Kennedy, Anne Weaver, Shubha Allard, Joan K. Morris, T. Mcloughlin, Laura E. Green
Publikováno v:
Transfusion Medicine. 28:56-59
SUMMARYBackground Haemorrhage is the leading cause of mortality during trauma. In 2012, London's Air Ambulance introduced Blood on Board (BOB), transfusing group O red cells (RBC) to trauma patients at the scene. Objectives This study assessed the im
Publikováno v:
International Journal of Research in Medical Sciences. 9:325
Background: Endourology which includes lower urinary tract (LUT) endoscopy, is an important component of standard urological practice worldwide. The objective of our study was to audit the LUT endoscopic procedures performed in Borno, a state in nort
Publikováno v:
Future Oncology. 9:1425-1431
Evaluation of: Dings PJ, Elferink MA, Strobbe LJ, de Wilt JH. The prognostic value of lymph node ratio in node-positive breast cancer: a Dutch nationwide population-based study. Ann. Surg. Oncol. 20(8), 2607–2614 (2013). Breast cancer (BC) is the m