Zobrazeno 1 - 10
of 273
pro vyhledávání: '"M, Lasker"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 3, Pp 612-624 (2008)
Long-chain 3-hydroxydicarboxylic acids (3-OHDCAs) are thought to arise via β-oxidation of the corresponding dicarboxylic acids (DCAs), although long-chain DCAs are neither readily transported into nor β-oxidized in mitochondria. We thus examined wh
Externí odkaz:
https://doaj.org/article/36b80259ebfc48d88f51150686f0d2be
Publikováno v:
Journal of the Association for Research in Otolaryngology. 18:827-835
Core body temperature has been shown to affect vestibular end-organ and nerve afferents so that their resting discharge rate and sensitivity increase with temperature. Our aim was to determine whether these changes observed in extracellular nerve rec
Autor:
David M. Lasker, László T. Tamás, Dominik Straumann, Béla Büki, Christopher J. Bockisch, Alexander A. Tarnutzer, Konrad P. Weber
Publikováno v:
Ear and Hearing. 38:e193-e199
OBJECTIVES: During head rotations, neuronal firing rates increase in ipsilateral and decrease in contralateral vestibular afferents. At low accelerations, this "push-pull mechanism" is linear. At high accelerations, however, the change of firing rate
Autor:
Jerome M. Lasker
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Journal of the American Medical Directors Association. 19:B15-B16
Publikováno v:
Experimental Brain Research. 230:127-135
The vestibulo-ocular reflex (VOR) acts to maintain images stable on the retina by rotating the eyes in exactly the opposite direction, but with equal magnitude, to head velocity. When viewing a near target, this reflex has an increased response to co
Publikováno v:
Experimental Brain Research. 210:651-660
Unilateral vestibular lesions cause marked asymmetry in the horizontal vestibulo-ocular reflex (VOR) during rapid head rotations, with VOR gain being lower for head rotations toward the lesion than for rotations in the opposite direction. Reducing th
Autor:
Jerome M. Lasker, Judy L. Raucy
Publikováno v:
Current Drug Metabolism. 11:806-814
The screening of new drug candidates for nuclear receptor activation can identify agents with the potential to produce drug-drug interactions or elicit adverse drug effects. The nuclear receptors of interest are those that control the expression of d
Autor:
Lloyd B. Minor, David M. Lasker
Publikováno v:
Journal of Vestibular Research. 19:159-170
Processes of vestibular compensation mediate recovery of many aspects of vestibular dysfunction following unilateral vestibular injury. The VOR in response to high-frequency, high-acceleration head movements, however, retains an enduring asymmetry. H
Publikováno v:
Experimental Brain Research. 200:269-275
The goal of this study was to determine the effect of changes in core body temperature on the resting discharge rate and sensitivity of vestibular-nerve afferents. Extracellular recordings were made from vestibular-nerve afferents innervating the sem