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Non-vitamin K antagonist oral anticoagulants (NOACs) attenuate valvular calcification in patients with severe aortic stenosis

Autor: M Kopytek, J Tarasiuk, S Wronski, A Undas, J Natorska

Publikováno v: European Heart Journal. 43

Background In vitro studies has demonstrated that non-vitamin K antagonist oral anticoagulants (NOACs) down-regulated the expression of proteins responsible for valve calcification and inflammation in valve interstitial cells (VICs) cultures. Aims Ou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1e41b62ff3e052c08e04e00092c417d
https://doi.org/10.1093/eurheartj/ehac544.3002

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An association of low-density lipoproteins and fibrinolysis in patients with severe aortic stenosis- valvular expression of fibrinolytic proteins

Autor: M Kopytek, A Undas, J Natorska

Publikováno v: European Heart Journal. 42

Background Aortic stenosis (AS) is associated with hyperlipidemia and hypofibrinolysis. The contribution of serum lipids to the valvular expression of fibrinolytic proteins is not known. Aims To evaluate whether fibrinolytic factors are present withi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3804555855107e1f40f4158436a26914
https://doi.org/10.1093/eurheartj/ehab724.1680

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Rivaroxaban attenuates valvular inflammation and tissue remodeling in patients with severe aortic stenosis

Autor: M Kopytek, M Zabczyk, A Undas, J Natorska

Publikováno v: European Heart Journal. 42

Background It has been demonstrated in a mouse model of atherosclerosis that non-vitamin K antagonist oral anticoagulants (NOACs) attenuate atherosclerotic plaque progression. However, it is not known whether NOACs can inhibit aortic stenosis (AS) pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a16751f868b5cbff09332627fba39054
https://doi.org/10.1093/eurheartj/ehab724.1681

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Rivaroxaban attenuates valvular calcification in patients with severe aortic stenosis

Autor: M. Zabczyk, M. Kopytek, J. Tarasiuk, S. Wronski, A. Undas, J. Natorska

Publikováno v: Atherosclerosis. 355:14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dd25df61c4d172f3988162014b236a8
https://doi.org/10.1016/j.atherosclerosis.2022.06.126

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Effects of direct oral anticoagulants on thromboelastographic parameters and fibrin clot properties in patients with venous thromboembolism

Autor: M, Kopytek, M, Zabczyk, J, Natorska, K P, Malinowski, A, Undas

Publikováno v: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 71(1)

Data concerning the impact of direct oral anticoagulants (DOACs) on the thromboelastography (TEG) indices in venousthromboembolism (VTE) patients are limited. The goal of this study was to compare the impact of DOACs on clot properties measured in wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a75bffd478dd98930f39e55194cacdc7
https://pubmed.ncbi.nlm.nih.gov/32350148

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Viscoelastic properties of plasma fibrin clots are similar in patients on rivaroxaban and vitamin K antagonists

Autor: M, Kopytek, M, Zabczyk, J, Natorska, J, Siudut, K P, Malinowski, P, Ptaszek, A, Glajcar, T, Goralczyk, A, Undas

Publikováno v: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 70(1)

Unfavorable fibrin clot features have been observed in patients with venous thromboembolism (VTE). We investigated whether rivaroxaban, a direct factor Xa inhibitor, and vitamin K antagonists (VKAs) can improve plasma clot viscoelastic properties. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8e7e5cec2bd04b65a605a15165e901b3
https://pubmed.ncbi.nlm.nih.gov/31019123

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Influence of Cryopreservation on Structural, Chemical, and Immunoenzymatic Properties of Aortic Valve Allografts

Autor: E. Majewska, L. Rudnicka-Sosin, Małgorzata Mazur, M. Kopytek, Z. Marcinkowska, M. Pawlikowski, R. Pfitzner, D. Barecka

Publikováno v: Transplantation proceedings. 50(7)

Objectives The problems in preparing (including cryopreservation) and implanting aortic valve allografts (AVAs) is widely elaborated, but some issues need explanation. Material and Methods Twenty AVAs cryopreserved in dimethylsulphoxide/RPMI solution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad38f7538c51249d64f51ea6846bcde
https://pubmed.ncbi.nlm.nih.gov/30177135

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