Zobrazeno 1 - 10 of 92 pro vyhledávání: '"M, Jakstadt"'
1
A Pronounced Inflammatory Activity Characterizes the Early Fracture Healing Phase in Immunologically Restricted Patients
Autor: Katharina Schmidt-Bleek, Timo Gaber, Annemarie Lang, Gerhard Schmidmaier, Georg Matziolis, Holger Hoff, Frank Buttgereit, Paula Hoff, M. Jakstadt, Georg N. Duda, Carsten Perka, Eric Röhner, C. Strehl, Gerd-Rüdiger Burmester, Dörte Huscher
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 3, p 583 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 3; Pages: 583
Immunologically restricted patients such as those with autoimmune diseases or malignancies often suffer from delayed or insufficient fracture healing. In human fracture hematomas and the surrounding bone marrow obtained from immunologically restricte
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea1bd84fb60569a490c889f514604ba6
http://europepmc.org/articles/PMC5372599
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2
High-Sensitivity Immunofluorescence Staining: A Comparison of the Liposome Procedure and the FASER Technique on mGR Detection
Autor: Gerd-Rüdiger Burmester, M. Hahne, Cornelia M. Spies, C. Strehl, M. Jakstadt, Alexander Scheffold, Paula Hoff, Frank Buttgereit, Timo Gaber
Publikováno v: Journal of Fluorescence. 23:509-518
Flow cytometry has become a widely-used and powerful tool for the characterization of cells according to their expression of specific proteins. However, sensitivity of this method is still limited since conventionally labeled antibodies can be conjug
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303017cd06cbe824d86a2fa53ffd7e7d
https://doi.org/10.1007/s10895-013-1163-4
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3
Osteoarthritis synovial fluid activates pro-inflammatory cytokines in primary human chondrocytes
Autor: Georg Matziolis, Paula Hoff, Gerd-Rüdiger Burmester, M. Jakstadt, Carsten Perka, Frank Buttgereit, Kristin Andreas, Eric Röhner, Timo Gaber
Publikováno v: International Orthopaedics. 37:145-151
Two of the most common joint diseases are rheumatoid arthritis (RA) and osteoarthritis (OA). Cartilage degradation and erosions are important pathogenetic mechanisms in both joint diseases and have presently gained increasing interest. The aim of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14283ffdf5c0ca7c77b87f2543cdfa7
https://doi.org/10.1007/s00264-012-1724-1
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4
OP0086 Alterations of immune cellular circadian rhythms in rheumatoid arthritis
Autor: Doerte Huscher, M. Jakstadt, Timo Gaber, J. Mazuch, Frank Buttgereit, B. Maier, G.-R. Burmester, N. Soboleva, Cornelia M. Spies, Paula Hoff, A. Kramer, Jacqueline Detert, Cam Loan Tran, A. Stoehr, Monique Fangradt, C. Strehl, Markus Wagegg, M. Hahne
Publikováno v: Annals of the Rheumatic Diseases. 71:82.2-82
Background The circadian variation of clinical symptoms and the underlying variation of cytokine and hormone levels in rheumatoid arthritis (RA) are well described and have already led to the successful application of chronotherapy with prednisone (B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::87000171dde9f1e3da863f96411003de
https://doi.org/10.1136/annrheumdis-2012-eular.1769
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6
THU0119 Impact of Amino-Pva Coated Nanoparticles on Viability and Cytokine Secretion of Human Immune Cells Obtained from Healthy Donors and Patients with Rheumatoid Arthritis
Autor: Heinrich Hofmann, Frank Buttgereit, G.-R. Burmester, Timo Gaber, M. Jakstadt, Lionel Maurizi, M. Hahne, Paula Hoff, C. Strehl
Publikováno v: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, BMJ Publishing Group, 2014, 73 (Suppl 2), pp.219.1-219. ⟨10.1136/annrheumdis-2014-eular.1379⟩
Background Nanotechnology has developed into a key technology of the 21st century. Over the recent years, the number of nanotechnical products has received an enormous boost. Furthermore, nanotechnology in medical applications provides new opportunit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dee6c0f94d58dac7cb01e1937259f4b
https://doi.org/10.1136/annrheumdis-2014-eular.1379
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7
OP0271 Differential regulatory functions of HIF-1α and HIF-2α during angiogenesis of human microvascular endothelial cells (HMECS)
Autor: S. Luetkecosmann, Monique Fangradt, Cam Loan Tran, C. Strehl, G.-R. Burmester, Georg N. Duda, Paula Hoff, Timo Gaber, M. Hahne, M. Jakstadt, Frank Buttgereit
Publikováno v: Annals of the Rheumatic Diseases. 71:148.1-148
Background Hypoxia and angiogenesis are features of inflamed and injured tissues. The transcription factors Hypoxia inducible factor (HIF)-1α and (HIF)-2α control cellular metabolic response to decreased oxygen tension thereby promoting angiogenesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5fec86da05e2628a65f938e43d95191
https://doi.org/10.1136/annrheumdis-2012-eular.1954
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8
AB0026 Pathophysiological hypoxia affects both redox state and il-2 signaling of human cd4+ t cells and concomitantly impairs survival and proliferation
Autor: G.-R. Burmester, Cam Loan Tran, C. Strehl, Frank Buttgereit, Saskia Schellmann, M. Hahne, M. Jakstadt, Timo Gaber
Publikováno v: Annals of the Rheumatic Diseases. 72:A793.3-A793
Background Rheumatoid arthritis (RA) is a chronic inflammatory disease of diarthrodial joints, characterized by the infiltration of immune cells, alterations of cellular redox state and pathophysiological local tissue hypoxia ( 2 ). Objectives We inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::069a5552c240f78f31c43e6b34314610
https://doi.org/10.1136/annrheumdis-2013-eular.2349
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9
THU0088 The Bioenergetic Role of HIF-1 and HIF-2 During Angiogenesis of Human Microvascular Endothelial Cells
Autor: Frank Buttgereit, G.-R. Burmester, M. Hahne, C. Strehl, F. Buttgereit, Timo Gaber, M. Jakstadt, Paula Hoff
Publikováno v: Annals of the Rheumatic Diseases. 72:A192.3-A193
Background Hypoxia and angiogenesis are features of inflamed and injured tissues. The transcription factors Hypoxia inducible factor (HIF)-1 and (HIF)-2 regulate the cellular and metabolic responses to reduced oxygen tensions thereby promoting angiog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::13ff7ee7ec2c7b424e52060707b0a8f0
https://doi.org/10.1136/annrheumdis-2013-eular.616
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10
THU0127 Functional activity of membrane-bound glucocorticoid receptors
Autor: Paula Hoff, M. Jakstadt, Timo Gaber, M. Hahne, C. Strehl, G.-R. Burmester, Frank Buttgereit
Publikováno v: Annals of the Rheumatic Diseases. 71:198.1-198
Background Glucocorticoids are among the most commonly used anti-inflammatory and immunosuppressive drugs in the treatment of rheumatic diseases. They exert their anti-inflammatory and immunosuppressive effects primarily via the cytosolic glucocortic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c5d813c870fedfa5303f53f0504950f
https://doi.org/10.1136/annrheumdis-2012-eular.2092
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