Zobrazeno 1 - 10
of 384
pro vyhledávání: '"M, Jablons"'
Autor:
Johannes R. Kratz, Jack Z. Li, Jessica Tsui, Jen C. Lee, Vivianne W. Ding, Arjun A. Rao, Michael J. Mann, Vincent Chan, Alexis J. Combes, Matthew F. Krummel, David M. Jablons
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Although surgery for early-stage lung cancer offers the best chance of cure, recurrence still occurs between 30 and 50% of the time. Why patients frequently recur after complete resection of early-stage lung cancer remains unclear. Using a l
Externí odkaz:
https://doaj.org/article/da70145a03394c46b36776a49d2c131a
Autor:
P. Jonathan Li, Jessica Tsui, Vivianne W. Ding, Alexis J. Combes, Matthew F. Krummel, David M. Jablons, Johannes R. Kratz
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 86-86 (2023)
OBJECTIVES/GOALS: Smoking is a well-established risk factor for lung cancer, but never smokers account for up to 25% of lung cancer cases. There is mounting evidence that lung cancer in never smokers is biologically distinct. We aim to characterize t
Externí odkaz:
https://doaj.org/article/49bee2f83b1c471abfe2a248884b1ec3
Autor:
Gavitt A. Woodard, Hannah Lee, Daffolyn Rachael Fels Elliott, Kirk D. Jones, Jasmine Wong, David M. Jablons, Kai Ihnken
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 14, Iss 1, Pp 1-4 (2019)
Abstract Introduction Many patients who undergo coronary artery bypass surgery have a prior history of cancer and potentially chest radiation which is a known risk factor for coronary atherosclerosis. Prior radiation increases fibrosis and can make t
Externí odkaz:
https://doaj.org/article/a3c5f45ec066441da814a24787eec590
Autor:
David H. Johnson, Roy S. Herbst, Corey J. Langer, Louis Fehrenbacher, William Novotny, Eric Holmgren, Jacques Gaudreault, John Nemunaitis, David M. Jablons, Fairooz F. Kabbinavar, Russell F. DeVore, Lisa A. Damico
Publikováno v:
Journal of Clinical Oncology. 41:2305-2312
Purpose To investigate the efficacy and safety of bevacizumab plus carboplatin and paclitaxel in patients with advanced or recurrent non-small-cell lung cancer. Patients and Methods In a phase II trial, 99 patients were randomly assigned to bevacizum
Autor:
Lisiena Hysenaj, Samantha Little, Kayla Kulhanek, Melia Magnen, Kriti Bahl, Oghenekevwe M. Gbenedio, Morgan Prinz, Lauren Rodriguez, Christopher Andersen, Arjun Arkal Rao, Alan Shen, Jean-Christophe Lone, Leonard C. Lupin-Jimenez, Luke R. Bonser, Nina K. Serwas, Eran Mick, Mir M. Khalid, Taha Y. Taha, Renuka Kumar, Jack Z. Li, Vivianne W. Ding, Shotaro Matsumoto, Mazharul Maishan, Bharath Sreekumar, Camille Simoneau, Irina Nazarenko, Michael G. Tomlinson, Khajida Khan, Anne von Gottberg, Alex Sigal, Mark R. Looney, Gabriela K. Fragiadakis, David M. Jablons, Charles R. Langelier, Michael Matthay, Matthew Krummel, David J. Erle, Alexis J. Combes, Anita Sil, Melanie Ott, Johannes R. Kratz, Jeroen P. Roose
Publikováno v:
Stem Cell Reports
Stem cell reports, vol 18, iss 3
Stem cell reports, vol 18, iss 3
Ancestral SARS coronavirus-2 (SARS-CoV-2) and variants of concern (VOC) caused a global pandemic with a spectrum of disease severity. The mechanistic explaining variations related to airway epithelium are relatively understudied. Here, we biobanked a
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Sequencing key cancer-driver genes using formalin-fixed, paraffin-embedded (FFPE) cancer tissues is becoming the standard for identifying the best treatment regimen. However, about 25% of all samples are rejected for genetic analyses for rea
Externí odkaz:
https://doaj.org/article/ac0e0e205e9a4dbf83fc291cf8779024
Autor:
Pasi A. Jänne, William G. Richards, Kiara J. Munir, Neal I. Lindeman, Vincent A. Miller, Phil J. Stephens, Lauren Young, Doron Lipson, David M. Jablons, Hidefumi Sasaki, Jhingook Kim, Seung-Il Park, Peter S. Hammerman, Dalia Ercan, Michael E. Dodge, Marzia Capelletti
Table S4. Characteristics of identified genomic rearrangements. The KIF5B-RET and the CD74-NTRK1 cases have been previously published (8, 15).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129024ccbe99f59b5d4e4e070eec4983
https://doi.org/10.1158/1078-0432.22457786
https://doi.org/10.1158/1078-0432.22457786
Autor:
Kathleen M. Giacomini, David M. Jablons, Zhidong Xu, Ligong Chen, Sook Wah Yee, Shuanglian Li, Swati S. More
Picoplatin, a third-generation platinum agent, is efficacious against lung cancers that are otherwise resistant or become refractory during platinum treatment. This effort was aimed at the determination of the influence of organic cation transporters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf799c78f4dcc9ba8e808631dee99f74
https://doi.org/10.1158/1535-7163.c.6531783
https://doi.org/10.1158/1535-7163.c.6531783
Autor:
David M. Jablons, Rafael Rosell, David R. Gandara, Mark Segal, Marcin Skrzypski, Miquel Taron, Biao He, Jae Y. Kim, M. Roshni Ray, Dan J. Raz
Purpose: Clinical staging does not adequately risk stratify patients with early stage non–small cell lung cancer. We sought to generate a real-time PCR (RT-PCR)–based prognostic model in patients with early stage lung adenocarcinoma, the dominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f4145e2527da32fd64413fd4443171
https://doi.org/10.1158/1078-0432.c.6516856.v1
https://doi.org/10.1158/1078-0432.c.6516856.v1
We describe the rational generation of small-molecule agents that suppress tumor cell growth by down-regulating canonical Wnt signaling. We first produced a chemical library of the derivatives of indole-2-ketones and carbinols; we then screened them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d70498a7e03f372ee175ff0c023ff6
https://doi.org/10.1158/1535-7163.c.6531474.v1
https://doi.org/10.1158/1535-7163.c.6531474.v1