Zobrazeno 1 - 10
of 89
pro vyhledávání: '"M, Humeau"'
Autor:
Viviane M. Andrade, Aaron Christensen-Quick, Joseph Agnes, Jared Tur, Charles Reed, Richa Kalia, Idania Marrero, Dustin Elwood, Katherine Schultheis, Mansi Purwar, Emma Reuschel, Trevor McMullan, Patrick Pezzoli, Kim Kraynyak, Albert Sylvester, Mammen P. Mammen, Pablo Tebas, J. Joseph Kim, David B. Weiner, Trevor R. F. Smith, Stephanie J. Ramos, Laurent M. Humeau, Jean D. Boyer, Kate E. Broderick
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-4 (2021)
Abstract Global surveillance has identified emerging SARS-CoV-2 variants of concern (VOC) associated with broadened host specificity, pathogenicity, and immune evasion to vaccine-induced immunity. Here we compared humoral and cellular responses again
Externí odkaz:
https://doaj.org/article/861f6b3de24f4eca965d9adae892bcdd
Autor:
Katherine Schultheis, Holly M Pugh, Janet Oh, Jacklyn Nguyen, Bryan Yung, Charles Reed, Neil Cooch, Jing Chen, Jian Yan, Kar Muthumani, Laurent M. Humeau, David B. Weiner, Kate E. Broderick, Trevor R. F. Smith
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 9, Pp 2165-2175 (2020)
Respiratory Syncytial virus (RSV) is a major threat to many vulnerable populations. There are currently no approved vaccines, and RSV remains a high unmet global medical need. Here we describe the employment of a novel synthetic DNA-encoded antibody
Externí odkaz:
https://doaj.org/article/d9cb672e710345b8835668cbf603e147
Autor:
Ami Patel, Jewell N. Walters, Emma L. Reuschel, Katherine Schultheis, Elizabeth Parzych, Ebony N. Gary, Igor Maricic, Mansi Purwar, Zeena Eblimit, Susanne N. Walker, Diana Guimet, Pratik Bhojnagarwala, Opeyemi S. Adeniji, Arthur Doan, Ziyang Xu, Dustin Elwood, Sophia M. Reeder, Laurent Pessaint, Kevin Y. Kim, Anthony Cook, Neethu Chokkalingam, Brad Finneyfrock, Edgar Tello-Ruiz, Alan Dodson, Jihae Choi, Alison Generotti, John Harrison, Nicholas J. Tursi, Viviane M. Andrade, Yaya Dia, Faraz I. Zaidi, Hanne Andersen, Mohamed Abdel-Mohsen, Mark G. Lewis, Kar Muthumani, J. Joseph Kim, Daniel W. Kulp, Laurent M. Humeau, Stephanie J. Ramos, Trevor R.F. Smith, David B. Weiner, Kate E. Broderick
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100420- (2021)
Summary: Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has had a dramatic global impact on public health and social and economic infrastructures. Here, we assess the immunogenicity and anamnestic protective efficacy in rhesus m
Externí odkaz:
https://doaj.org/article/b251aab9f925454e8c8c047ebbca4faa
Autor:
Jingjing Jiang, Preeti Banglore, Kathleen A. Cashman, Connie S. Schmaljohn, Katherine Schultheis, Holly Pugh, Jacklyn Nguyen, Laurent M. Humeau, Kate E. Broderick, Stephanie J. Ramos
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 9, Pp 2066-2074 (2019)
Lassa virus (LASV) is a hemorrhagic fever virus of the Arenaviridae family with high rates of mortality and co-morbidities, including chronic seizures and permanent bilateral or unilateral deafness. LASV is endemic in West Africa and Lassa fever acco
Externí odkaz:
https://doaj.org/article/1b1f1038310b49d6b16a6be5bb6f7c01
Autor:
Ami Patel, Emma L. Reuschel, Ziyang Xu, Faraz I. Zaidi, Kevin Y. Kim, Dana P. Scott, Janess Mendoza, Stephanie Ramos, Regina Stoltz, Friederike Feldmann, Atsushi Okumura, Kimberly Meade-White, Elaine Haddock, Tina Thomas, Rebecca Rosenke, Jamie Lovaglio, Patrick W. Hanley, Greg Saturday, Kar Muthumani, Heinz Feldmann, Laurent M. Humeau, Kate E. Broderick, David B. Weiner
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
Emerging coronaviruses from zoonotic reservoirs, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have been
Externí odkaz:
https://doaj.org/article/6a1a7018c4ed4003a8f49aaa184d7f1a
Autor:
Pablo Tebas, ShuPing Yang, Jean D. Boyer, Emma L. Reuschel, Ami Patel, Aaron Christensen-Quick, Viviane M. Andrade, Matthew P. Morrow, Kimberly Kraynyak, Joseph Agnes, Mansi Purwar, Albert Sylvester, Jan Pawlicki, Elisabeth Gillespie, Igor Maricic, Faraz I. Zaidi, Kevin Y. Kim, Yaya Dia, Drew Frase, Patrick Pezzoli, Katherine Schultheis, Trevor R.F. Smith, Stephanie J. Ramos, Trevor McMullan, Karen Buttigieg, Miles W. Carroll, John Ervin, Malissa C. Diehl, Elliott Blackwood, Mammen P. Mammen, Jessica Lee, Michael J. Dallas, Ami Shah Brown, Jacqueline E. Shea, J.Joseph Kim, David B. Weiner, Kate E. Broderick, Laurent M. Humeau
Publikováno v:
EClinicalMedicine, Vol 31, Iss , Pp 100689- (2021)
Background: A vaccine against SARS-CoV-2 is of high urgency. Here the safety and immunogenicity induced by a DNA vaccine (INO-4800) targeting the full length spike antigen of SARS-CoV-2 are described. Methods: INO-4800 was evaluated in two groups of
Externí odkaz:
https://doaj.org/article/a9f1cb97a12243469984e15dede48ebe
Autor:
Ziyang Xu, Megan C. Wise, Neethu Chokkalingam, Susanne Walker, Edgar Tello‐Ruiz, Sarah T. C. Elliott, Alfredo Perales‐Puchalt, Peng Xiao, Xizhou Zhu, Ruth A. Pumroy, Paul D. Fisher, Katherine Schultheis, Eric Schade, Sergey Menis, Stacy Guzman, Hanne Andersen, Kate E. Broderick, Laurent M. Humeau, Kar Muthumani, Vera Moiseenkova‐Bell, William R. Schief, David B. Weiner, Daniel W. Kulp
Publikováno v:
Advanced Science, Vol 7, Iss 8, Pp n/a-n/a (2020)
Abstract Nanotechnologies are considered to be of growing importance to the vaccine field. Through decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit improved humoral immunity. However, significant practical and m
Externí odkaz:
https://doaj.org/article/a5cfd50706de4598866740c702c06b33
Autor:
Sarah T. C. Elliott, Nicole L. Kallewaard, Ebony Benjamin, Leslie Wachter-Rosati, Josephine M. McAuliffe, Ami Patel, Trevor R. F. Smith, Katherine Schultheis, Daniel H. Park, Seleeke Flingai, Megan C. Wise, Janess Mendoza, Stephanie Ramos, Kate E. Broderick, Jian Yan, Laurent M. Humeau, Niranjan Y. Sardesai, Kar Muthumani, Qing Zhu, David B. Weiner
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-9 (2017)
Nucleic acid delivery: Instant, wide-ranging protection against influenza A and B A novel innoculation technique involving the injection of antibody-producing plasmid DNA has shown to be effective against influenza in mice. The flu is responsible for
Externí odkaz:
https://doaj.org/article/eacd8d537f1948d3bf6f77c99669bab8
Autor:
Jingjing Jiang, Stephanie J. Ramos, Preeti Bangalore, Dustin Elwood, Kathleen A. Cashman, Sagar B. Kudchodkar, Katherine Schultheis, Holly Pugh, Jewell Walters, Jared Tur, Jian Yan, Ami Patel, Kar Muthumani, Connie S. Schmaljohn, David B. Weiner, Laurent M. Humeau, Kate E. Broderick
Publikováno v:
Viruses, Vol 13, Iss 3, p 382 (2021)
The emergence of multiple concurrent infectious diseases localized in the world creates a complex burden on global public health systems. Outbreaks of Ebola, Lassa, and Marburg viruses in overlapping regions of central and West Africa and the co-circ
Externí odkaz:
https://doaj.org/article/06292c7bc4954bc78774733aa152463f
Publikováno v:
Journal of Investigative Dermatology. 143:S128