Zobrazeno 1 - 10
of 90
pro vyhledávání: '"M, Hinchcliffe"'
Autor:
A.M. Cheff, S.J. Warwood, J.P. Stenz, Charles Richardson, S.D. Klas, C.L. Olds, Marlene S. Williams, C.R. Petrie, M. Hinchcliffe, S. Wimer
Publikováno v:
Vaccine. 26:5494-5502
Here we confirm that intranasal (IN) dry powder anthrax vaccine formulations are able to protect rabbits against aerosol challenge 9 weeks after a single immunization. The optimum dose of rPA in our dry powder anthrax vaccine formulation in rabbits w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17314f3db95b5fd1a16f909ac2564de7
https://doi.org/10.1016/j.vaccine.2008.07.062
https://doi.org/10.1016/j.vaccine.2008.07.062
Autor:
Ramzi T Younis, Annette M. Hinchcliffe, Ann K. White, Jay N. Dolitsky, Kelvin C. Lee, Eric L. Mansfield, John P. Bent
Publikováno v:
Ear, Nose & Throat Journal. 83:4-13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b7f01a424eb6418ae257ac9da1045f8
https://doi.org/10.1177/014556130408303s02
https://doi.org/10.1177/014556130408303s02
Publikováno v:
Pharmaceutical Research. 20:1474-1484
Purpose. Investigate the effect of blood sampling site and physicochemical characteristics of drugs on the pharmacokinetic (PK) parameters obtained after intravenous and nasal administration in sheep and compare results with computer simulations. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ad41d4afb956d344f2629e931d30f9
https://doi.org/10.1023/a:1025722614154
https://doi.org/10.1023/a:1025722614154
Autor:
H. Norbury, Inderjit Jabbal-Gill, Stanley Stewart Davis, Lisbeth Illum, M Hinchcliffe, R. Nankervis, Watts Peter, A. N. Fisher
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 301:391-400
Morphine administered nasally to humans as a simple solution is only absorbed to a limited degree, with a bioavailability of the order of 10% compared with intravenous administration. This article describes the development of novel nasal morphine for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7668cbefcb0060d16a17e76db6e8da6f
https://doi.org/10.1124/jpet.301.1.391
https://doi.org/10.1124/jpet.301.1.391
Autor:
Inderjit Jabbal-Gill, Watts Peter, A. M. Dyer, R Nankervis, Lisbeth Illum, M Hinchcliffe, J. Castile, Alan Smith
Publikováno v:
Pharmaceutical Research. 19:998-1008
Purpose. To investigate whether the widely accepted advantages associated with the use of chitosan as a nasal drug delivery system, might be further improved by application of chitosan formulated as nanoparticles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a41c2d00a7fee233c38c6f38288ed2b
https://doi.org/10.1023/a:1016418523014
https://doi.org/10.1023/a:1016418523014
Publikováno v:
Advanced Drug Delivery Reviews. 51:81-96
A variety of different types of nasal vaccine systems has been described to include cholera toxin, microspheres, nanoparticles, liposomes, attenuated virus and cells and outer membrane proteins (proteosomes). The present review describes our work on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23412a5ce220fb20457d0cccdd1cd8b
https://doi.org/10.1016/s0169-409x(01)00171-5
https://doi.org/10.1016/s0169-409x(01)00171-5
Publikováno v:
International Journal of Pharmaceutics. 217:183-191
This paper describes the clearance characteristics of two bioadhesive nasal delivery systems in the form of chitosan microspheres and chitosan solution, from the nasal cavity of conscious sheep. The pattern of deposition and clearance of the nasal do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33028c0f92084c7a1af6a3bbbaee044
https://doi.org/10.1016/s0378-5173(01)00602-0
https://doi.org/10.1016/s0378-5173(01)00602-0
Publikováno v:
Journal of Pharmacy and Pharmacology. 53:33-39
The gastrointestinal transit of liquid, pellet and tablet formulations was measured under fasted conditions in the domestic pig (n = 4) using the technique of gamma scintigraphy. The mean times for 50% gastric emptying for liquid and pellet systems w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae9951d8b83cf6f8bfe29c77dd17070
https://doi.org/10.1211/0022357011775163
https://doi.org/10.1211/0022357011775163
Autor:
Mohamed Lachab, A. Giles Davies, Subhasish Chakraborty, Edmund H. Linfield, Nicholas M. Hinchcliffe, Suraj P. Khanna
Publikováno v:
Physica E: Low-dimensional Systems and Nanostructures. 40:1859-1861
Results are presented for two GaAs/AlGaAs quantum cascade laser (QCL) structures that emit at frequencies of 2.59 and 2.75 THz. Both structures have a nominally identical, bound-to-continuum active region design, and the difference between their emis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb5d99857a0104ae3f7c2fbe05b85303
https://doi.org/10.1016/j.physe.2007.08.126
https://doi.org/10.1016/j.physe.2007.08.126
Autor:
Alexander Giles Davies, Robert W. Kelsall, Suraj P. Khanna, Paul Harrison, C. A. Evans, Paul Dean, N. M. Hinchcliffe, Zoran Ikonic, Edmund H. Linfield, L. Lever
Publikováno v:
Optics express. 17(22)
Terahertz frequency quantum cascade lasers (THz QCLs) are compact solid-state sources of terahertz radiation that were first demonstrated in 2002. They have a broad range of potential applications ranging from gas sensing and non-destructive testing,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6418ea8c866432214168264eeac7e0e
https://pubmed.ncbi.nlm.nih.gov/19997216
https://pubmed.ncbi.nlm.nih.gov/19997216