Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M, Higginbotham"'
Autor:
M Higginbotham, Rebekah Molyneux
Publikováno v:
Journal of Kidney Care. 4:306-312
Over the last 5 years, there has been a rapid increase in the incidence of infection and colonisation by multi-drug resistant carbapenemase-producing organisms in the UK. Renal patients are especially susceptible to infection. This article describes
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Publikováno v:
Current Protocols in Stem Cell Biology
Reprogramming somatic cells to generate induced pluripotent stem cells (iPSCs) has presented the biomedical community with a powerful platform to develop new models for human disease. To fully realize the promise of this technology in cell therapy an
Autor:
Steven E Spencer, James K. Aden, Stephanie E Giancola, John M Higginbotham, Alice E Barsoumian, Deena E Sutter
Publikováno v:
Family Practice.
Background Acute uncomplicated cystitis is one of the most common diagnoses for which antibiotic treatment is prescribed in the outpatient setting. Despite the availability of national guidelines, there remains a wide pattern in prescriber choices fo
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Publikováno v:
Journal of Virology. 89:10260-10272
Adenovirus E4-ORF3 and E1B-55K converge in subverting critical overlapping cellular pathways to facilitate virus replication. Here, we show that E1B-55K and E4-ORF3 induce sumoylation and the assembly of SUMO2/3 viral genome replication domains. Usin
Autor:
Andreas Troester, Lorna Kennedy, Mari C. M. Higginbotham, Anita G. Lindsay, Magnus W. P. Bebbington
Publikováno v:
Tetrahedron. 71(4):727-737
Six-membered cyclic sulfamidates are prepared in high yields by treatment of allenic sulfamates with readily available Ph3PAuNTf2. The reaction enables formation of N-substituted quaternary centres in high yields. The relative stereochemistry has bee
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 26(9)
Revealing the spatial arrangement of molecules within a tissue through immunohistochemistry (IHC) is an invaluable tool in biomedical research and clinical diagnostics. Choosing both the appropriate antibody and amplification system is paramount to t
Autor:
Li Huang, Suzette Farber-Katz, Layton H. Smith, John R. Cashman, Alice Kiselyuk, Friedhelm Schroeder, Paul J. Bushway, Yong Cang, Seung-Hee Lee, Mark Mercola, Benjamin Spangler, Heather A. Hostetler, Fred Levine, Jennifer M. Higginbotham, Pamela Itkin-Ansari, Sonalee Athavankar, Hudson H. Freeze, Adam D. Richardson, Mingjun Zhang, Anthony B. Pinkerton, Tom Cohen, Mao Ye, Mariam Rodriguez-Lee, Marcia I. Dawson
Publikováno v:
Chemistry & Biology. 19:806-818
SummaryHepatocyte nuclear factor (HNF)4α is a central regulator of gene expression in cell types that play a critical role in metabolic homeostasis, including hepatocytes, enterocytes, and pancreatic β cells. Although fatty acids were found to occu
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