The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells

Autor: Rob C. Hoeben, Martijn J. W. E. Rabelink, W.J.F. van der Vijgh, M A I Abou El Hassan, M Heijn, Aalt Bast

Publikováno v: Abou El Hassan, MA, Heijn, M, Rabelink, MJ, van der Vijgh, W J F & Hoeben, RC 2003, ' The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells. ', Cancer Gene Therapy, vol. 10, no. 4, pp. 270-7 . https://doi.org/10.1038/sj.cgt.7700564
Cancer Gene Therapy, 10(4), 270-7. Nature Publishing Group
Cancer Gene Therapy, 10(4), 270-277. Nature Publishing Group

The protective effect of cardiac gene transfer of CuZn-sod in comparison with the cardioprotector monohydroxyethylrutoside against doxorubicin-induced cardiotoxicity in cultured cells.Abou El Hassan MA, Heijn M, Rabelink MJ, van der Vijgh WJ, Bast A,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aea922a0a6828a24b9c769f343594e6
https://research.vumc.nl/en/publications/50936e98-9a5b-432e-bd1b-f0ae23434943

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies

Autor: G L, Scheffer, M, Kool, M, Heijn, M, de Haas, A C, Pijnenborg, J, Wijnholds, A, van Helvoort, M C, de Jong, J H, Hooijberg, C A, Mol, M, van der Linden, J M, de Vree, P, van der Valk, R P, Elferink, P, Borst, R J, Scheper

Publikováno v: Cancer research. 60(18)

Tumor cells may display a multidrug resistance phenotype by overexpression of ATP binding cassette transporter genes such as multidrug resistance (MDR) 1 P-glycoprotein (P-gp) or the multidrug resistance protein 1 (MRP1). MDR3 P-gp is a close homolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7ad3f3eca287171f5e83e051df87f576
https://pubmed.ncbi.nlm.nih.gov/11016657

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione

Autor: C C, Paulusma, M A, van Geer, R, Evers, M, Heijn, R, Ottenhoff, P, Borst, R P, Oude Elferink

Publikováno v: The Biochemical journal. 338

The canalicular multispecific organic anion transporter (cMOAT), a member of the ATP-binding cassette transporter family, mediates the transport of a broad range of non-bile salt organic anions from liver into bile. cMOAT-deficient Wistar rats (TR-)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0ce7f57727cf63eca27b3f448ea3cd8
https://pubmed.ncbi.nlm.nih.gov/10024515

Redistribution of canalicular organic anion transport activity in isolated and cultured rat hepatocytes

Autor: H, Roelofsen, C T, Bakker, B, Schoemaker, M, Heijn, P L, Jansen, R P, Elferink

Publikováno v: Hepatology (Baltimore, Md.). 21(6)

The hepatocanalicular transport of a large number of organic anions, such as bilirubin glucuronides and glutathione conjugates in the rat, is mediated by an adenosine triphosphate (ATP)-dependent transport system, which is termed canalicular multispe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4c406a3e6be481a4b092fa244df15dc6
https://pubmed.ncbi.nlm.nih.gov/9021974

Accumulation of organic anion in intracellular vesicles of cultured rat hepatocytes is mediated by the canalicular multispecific organic anion transporter

Autor: Roelof Ottenhoff, Esther Middelkoop, Conny T. M. Bakker, Han Roelofsen, M Heijn, Ronald P.J. Oude Elferink, Peter L.M. Jansen

Publikováno v: Hepatology (Baltimore, Md.), 17(3), 434-444. John Wiley and Sons Ltd

Transport of organic anions within hepatocytes and the possible involvement of intracellular vesicles were studied with fluorescence microscopy. For this purpose monochlorobimane, a nonfluorescent hydrophobic compound that readily permeates into cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1273a141dabb29c0bd306fe8a81cc84b
https://pure.amc.nl/en/publications/accumulation-of-organic-anion-in-intracellular-vesicles-of-cultured-rat-hepatocytes-is-mediated-by-the-canalicular-multispecific-organic-anion-transporter(98b4b845-5357-43b5-86e4-5952eb27b612).html