Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M, Heidel"'
Autor:
Rachel L Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T Shah, Justin J Miller, Andrew J Jezewski, Marwa O Mikati, Xu Wang, Robert C Brothers, Kenneth M Heidel, Damon M Osbourn, Carey-Ann D Burnham, Sophie Alvarez, Stephanie A Fritz, Cynthia S Dowd, Joseph M Jez, Audrey R Odom John
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1007806 (2020)
Coagulase-positive staphylococci, which frequently colonize the mucosal surfaces of animals, also cause a spectrum of opportunistic infections including skin and soft tissue infections, urinary tract infections, pneumonia, and bacteremia. However, re
Externí odkaz:
https://doaj.org/article/5dc53d519c85411dae65c54b8c5190b9
Autor:
Andrea Barthel, Heiko Vogel, Yannick Pauchet, Gerhard Pauls, Grit Kunert, Astrid T. Groot, Wilhelm Boland, David G. Heckel, Hanna M. Heidel-Fischer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Certain plants in the nightshade family contain withanolides, defensive chemicals known to be harmful to most insect herbivores. Here, Barthel et al. show that a moth species that is a specialist herbivore of these plants benefits from the compounds
Externí odkaz:
https://doaj.org/article/8c44addc612f4cc9bf215a9a07b80019
Autor:
Cynthia S. Dowd, Kenneth M. Heidel
Publikováno v:
Future Med Chem
Phosphonates, often used as isosteric replacements for phosphates, can provide important interactions with an enzyme. Due to their high charge at physiological pH, however, permeation into cells can be a challenge. Protecting phosphonates as prodrugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a149d7eb8911abdc4f85d475f10ab53
https://doi.org/10.4155/fmc-2018-0591
https://doi.org/10.4155/fmc-2018-0591
Autor:
Michael Reichelt, Masashi Murakami, Ai Sato, Heiko Vogel, Yu Okamura, Masami Yokota Hirai, Yuji Sawada, Hanna M. Heidel-Fischer, Natsumi Tsuzuki
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Specialist herbivores have often evolved highly sophisticated mechanisms to counteract defenses mediated by major plant secondary-metabolites. Plant species of the herbivore host range often display high chemical diversity and it is not well understo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722ec016d100fa8e1cd66f03fa73b6d2
http://link.springer.com/article/10.1038/s41598-019-43703-8
http://link.springer.com/article/10.1038/s41598-019-43703-8
Autor:
Marwa O. Mikati, Yasaman Barekatain, Damon M. Osbourn, Carey-Ann D. Burnham, Rachel L. Edwards, Victoria C. Yan, Cynthia S. Dowd, Florian L. Muller, Naomi Ghebremichael, Justin J. Miller, Kenneth M. Heidel, Audrey R. Odom John, Ishaan T. Shah
Publikováno v:
ACS Infect Dis
With the rising prevalence of multidrug-resistance, there is an urgent need to develop novel antibiotics. Many putative antibiotics demonstrate promising in vitro potency but fail in vivo due to poor drug-like qualities (e.g. serum half-life, oral ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da808b9eb618297e0a5c7d55b8690ea8
https://doi.org/10.1101/2020.07.23.214460
https://doi.org/10.1101/2020.07.23.214460
Publikováno v:
Molecular Ecology
Adaptive traits that enable organisms to conquer novel niches and experience subsequent diversification are ecologically and evolutionarily important. The larvae of Pieris butterflies express nitrile-specifier proteins (NSPs), a key innovation for ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223c34406847cdfbd2ddb9ae0c333c07
https://doi.org/10.1101/627182
https://doi.org/10.1101/627182
Autor:
Rachel L. Edwards, Isabel Heueck, Soon Goo Lee, Ishaan T. Shah, Andrew J. Jezewski, Justin J. Miller, Marwa O. Mikati, Xu Wang, Robert C. Brothers, Kenneth M. Heidel, Carey-Ann D. Burnham, Sophie Alvarez, Stephanie A. Fritz, Cynthia S. Dowd, Joseph M. Jez, Audrey R. Odom John
Coagulase-positive staphylococci, which frequently colonize the mucosal surfaces of animals, also cause a spectrum of opportunistic infections including skin and soft tissue infections, urinary tract infections, pneumonia, and bacteremia. However, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e198b917912c8349bb520cae7827e58f
https://doi.org/10.1101/626325
https://doi.org/10.1101/626325
Autor:
David G. Heckel, Natalie Wielsch, Hanna M. Heidel-Fischer, Seung-Joon Ahn, Heiko Vogel, Juergen Kroymann, Michael Reichelt, Roy Kirsch, Simon W. Baxter
Publikováno v:
Molecular Biology and Evolution
Molecular Biology and Evolution, Oxford University Press (OUP), 2019, ⟨10.1093/molbev/msz019⟩
Molecular Biology and Evolution, Oxford University Press (OUP), 2019, ⟨10.1093/molbev/msz019⟩
Antagonistic chemical interactions between herbivorous insects and their host plants are often thought to co-evolve in a stepwise process, with an evolutionary innovation on one side being countered by a corresponding advance on the other. Glucosinol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db16d6f0cdd461672fb8b97484e568ba
https://hal.archives-ouvertes.fr/hal-02104506
https://hal.archives-ouvertes.fr/hal-02104506
Autor:
Hanna M. Heidel-Fischer, Stephen I. Wright, Jocelyn C. Hall, J. Chris Pires, Thomas E. Bureau, Christopher W. Wheat, Ann Smithson, Michael S. Barker, David G. Heckel, Heiko Vogel, Michelle Tang, Patrick P. Edger, M. Eric Schranz, Jadranka Rota, Claude W. dePamphilis, Michaël Bekaert, Adrian E. Platts, Johannes A. Hofberger, Gavin C. Conant, Matthieu Blanchette, Niklas Wahlberg, Joshua P. Der, Eric K. Wafula, Gernot Glöckner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 112 (2015) 27
Proceedings of the National Academy of Sciences of the United States of America, 112(27): 8362–8366
Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8362-8366
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 112(27): 8362–8366
Proceedings of the National Academy of Sciences of the United States of America, 112(27), 8362-8366
Proceedings of the National Academy of Sciences of the United States of America
Coevolutionary interactions are thought to have spurred the evolution of key innovations and driven the diversification of much of life on Earth. However, the genetic and evolutionary basis of the innovations that facilitate such interactions remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58cd97f59479d4543b0671342b23f60d
https://doi.org/10.1073/pnas.1503926112
https://doi.org/10.1073/pnas.1503926112
Autor:
Hanna M. Heidel-Fischer, Heiko Vogel
Publikováno v:
Current Opinion in Insect Science. 8:8-14
During feeding, herbivorous insects are exposed to an array of plant defensive compounds. In this review, we examine molecular mechanisms of insect adaptation to these toxic metabolites. We discuss both the importance of evolutionary variation of exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ba7ccfb8fa9a3a77875971285a2fe9
https://doi.org/10.1016/j.cois.2015.02.004
https://doi.org/10.1016/j.cois.2015.02.004