Zobrazeno 1 - 10
of 21 313
pro vyhledávání: '"M, Hayashi"'
Autor:
Camille R. Simoneau, Pei-Yi Chen, Galen K. Xing, Jennifer M. Hayashi, Irene P. Chen, Mir M. Khalid, Nathan L. Meyers, Taha Y. Taha, Kristoffer E. Leon, Rahul K. Suryawanshi, Maria McCavitt-Malvido, Tal Ashuach, Krystal A. Fontaine, Lauren Rodriguez, Bastian Joehnk, Keith Walcott, Sreelakshmi Vasudevan, Xiaohui Fang, Mazharul Maishan, Shawn Schultz, Jeroen P. Roose, Michael A. Matthay, Anita Sil, Mehrdad Arjomandi, Nir Yosef, Melanie Ott
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract As SARS-CoV-2 continues to spread worldwide, tractable primary airway cell models that recapitulate the cell-intrinsic response to arising viral variants are needed. Here we describe an adult stem cell-derived human airway organoid model ove
Externí odkaz:
https://doaj.org/article/2b9300e935d0405aa6dbdcaf44fa0f99
Autor:
T. Ono, D. Muraoka, M. Hayashi, M. Yorifuji, A. Dazai, S. Omoto, T. Tanaka, T. Okamura, G. Onitsuka, K. Sudo, M. Fujii, R. Hamanoue, M. Wakita
Publikováno v:
Biogeosciences, Vol 21, Pp 177-199 (2024)
The pH of coastal seawater varies based on several local forcings, such as water circulation, terrestrial inputs, and biological processes, and these forcings are changing along with global climate change. Understanding the mechanism of pH variation
Externí odkaz:
https://doaj.org/article/38c23bde49f54905a27d6a2a978034fc
Autor:
H. Shiogama, H. Tatebe, M. Hayashi, M. Abe, M. Arai, H. Koyama, Y. Imada, Y. Kosaka, T. Ogura, M. Watanabe
Publikováno v:
Earth System Dynamics, Vol 14, Pp 1107-1124 (2023)
Single model initial-condition large ensembles (LEs) are a useful approach to understand the roles of forced responses and internal variability in historical and future climate change. Here, we produce one of the largest ensembles thus far using the
Externí odkaz:
https://doaj.org/article/2c6ab96af2a640308718f0fff7c36942
Autor:
Taha Y. Taha, Irene P. Chen, Jennifer M. Hayashi, Takako Tabata, Keith Walcott, Gabriella R. Kimmerly, Abdullah M. Syed, Alison Ciling, Rahul K. Suryawanshi, Hannah S. Martin, Bryan H. Bach, Chia-Lin Tsou, Mauricio Montano, Mir M. Khalid, Bharath K. Sreekumar, G. Renuka Kumar, Stacia Wyman, Jennifer A. Doudna, Melanie Ott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Although the SARS-CoV-2 Omicron variant (BA.1) spread rapidly across the world and effectively evaded immune responses, its viral fitness in cell and animal models was reduced. The precise nature of this attenuation remains unknown as genera
Externí odkaz:
https://doaj.org/article/49493a60ddbb416184e22cc9169a5aac
Autor:
Makoto Horiuchi, Christian J. Hinderer, Jenny A. Greig, Cecilia Dyer, Elizabeth L. Buza, Peter Bell, Jessica A. Chichester, Peter M. Hayashi, Hanying Yan, Tamara Goode, James M. Wilson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 272-280 (2022)
Gene therapy using neurotropic adeno-associated virus vectors represents an emerging solution for genetic disorders affecting the central nervous system. The first approved central nervous system-targeting adeno-associated virus gene therapy, Zolgens
Externí odkaz:
https://doaj.org/article/47d10615a3624fa0872c118998bf302a
Autor:
M. Hayashi, N. Salvetat, C. Cayzac, F. J. Checa-Robles, C. Lozano, J.-D. Abraham, B. Dubuc, S. Mereuze, J. V. Nani, F. Molina, E. Brietske, D. Weissmann
Publikováno v:
European Psychiatry, Vol 66, Pp S573-S573 (2023)
Introduction Bipolar disorder (BD) is a severe mental disorder associated with functional impairment, high disability and premature mortality. Modifications of editing in mRNA of serotonin receptor subtype 2C (5-HTR2c) was reported by us in depressed
Externí odkaz:
https://doaj.org/article/d2a05c1d3d224aa98d5c71213c737bc6
Publikováno v:
Atmospheric Measurement Techniques, Vol 15, Pp 435-458 (2022)
Using data from the Infrared Atmospheric Sounding Interferometer (IASI) measurements of volcanic ash clouds (VACs) and radiative transfer calculations, we attempt to simulate the measured brightness temperature spectra (BTS) of volcanic ash aerosols
Externí odkaz:
https://doaj.org/article/730971a022b846b5a201b9cd5bf31678
Autor:
Marius Walter, Irene P Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L Lam, Jennifer M Hayashi, Andrew Cruz, Samah Shah, Frank W Soveg, John D Gross, Nevan J Krogan, Keith R Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010811 (2022)
SARS-CoV-2 non-structural protein Nsp14 is a highly conserved enzyme necessary for viral replication. Nsp14 forms a stable complex with non-structural protein Nsp10 and exhibits exoribonuclease and N7-methyltransferase activities. Protein-interactome
Externí odkaz:
https://doaj.org/article/19538024418c4582aee777208e569149
Autor:
Yusuke Matsui, Lin Li, Mary Prahl, Arianna G. Cassidy, Nida Ozarslan, Yarden Golan, Veronica J. Gonzalez, Christine Y. Lin, Unurzul Jigmeddagva, Megan A. Chidboy, Mauricio Montano, Taha Y. Taha, Mir M. Khalid, Bharath Sreekumar, Jennifer M. Hayashi, Pei-Yi Chen, G. Renuka Kumar, Lakshmi Warrier, Alan H.B. Wu, Dongli Song, Priya Jegatheesan, Daljeet S. Rai, Balaji Govindaswami, Jordan Needens, Monica Rincon, Leslie Myatt, Ifeyinwa V. Asiodu, Valerie J. Flaherman, Yalda Afshar, Vanessa L. Jacoby, Amy P. Murtha, Joshua F. Robinson, Melanie Ott, Warner C. Greene, Stephanie L. Gaw
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Pregnancy confers unique immune responses to infection and vaccination across gestation. To date, there are limited data comparing vaccine- and infection-induced neutralizing Abs (nAbs) against COVID-19 variants in mothers during pregnancy. We analyz
Externí odkaz:
https://doaj.org/article/e263e98537e14ce58365d0a07e07c9dc
Autor:
C. M. DeBeer, H. S. Wheater, J. W. Pomeroy, A. G. Barr, J. L. Baltzer, J. F. Johnstone, M. R. Turetsky, R. E. Stewart, M. Hayashi, G. van der Kamp, S. Marshall, E. Campbell, P. Marsh, S. K. Carey, W. L. Quinton, Y. Li, S. Razavi, A. Berg, J. J. McDonnell, C. Spence, W. D. Helgason, A. M. Ireson, T. A. Black, M. Elshamy, F. Yassin, B. Davison, A. Howard, J. M. Thériault, K. Shook, M. N. Demuth, A. Pietroniro
Publikováno v:
Hydrology and Earth System Sciences, Vol 25, Pp 1849-1882 (2021)
The interior of western Canada, like many similar cold mid- to high-latitude regions worldwide, is undergoing extensive and rapid climate and environmental change, which may accelerate in the coming decades. Understanding and predicting changes in co
Externí odkaz:
https://doaj.org/article/946be1658aca485c8322d6862b85c1ab