Zobrazeno 1 - 10
of 191
pro vyhledávání: '"M, Hanocq"'
Publikováno v:
Pharmacy and Pharmacology Communications. 5:575-578
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be9da158d25c99bfa7c5d98cb132be91
https://doi.org/10.1211/146080899128735379
https://doi.org/10.1211/146080899128735379
Autor:
L. Maes, G. Timperman, Jörg Holenz, M. Hanocq, Torsten Geuder, Guido François, G. Bringmann, J. Dubois, L. Ake Assi
Publikováno v:
Annals of Tropical Medicine & Parasitology. 90:115-123
The growth-inhibiting activities of naturally occurring naphthylisoquinoline alkaloids against asexual blood stages of Plasmodium falciparum (NF 54, clone A1A9) and P. berghei (Anka) were studied in vitro. Three of the alkaloids [7-epi-dioncophylline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0365e937b5bb6404b70a13d8a734b70b
https://doi.org/10.1080/00034983.1996.11813035
https://doi.org/10.1080/00034983.1996.11813035
Publikováno v:
Cell biology and toxicology. 14(6)
The effects of a series of bisbenzyldiamine analogs have been tested on P388D1 cell line in vitro. Their effects on cell growth, polyamine oxidase (PAO) activity and intracellular polyamine content were determined. The cytotoxicity tests were perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ef4b4eeef003328828d9565fb41cf4a
https://pubmed.ncbi.nlm.nih.gov/9879934
https://pubmed.ncbi.nlm.nih.gov/9879934
Publikováno v:
Die Pharmazie. 53(1)
In order to regulate simultaneously the biosynthesis and the transport of natural polyamines, the synthesis of a series of N-methylated analogues of N,N1-Bis(benzyl)-alkanediamines (propanediamine and butanediamine) was achieved and the cytotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e1c13b149586993602f0a08b7d8d2ee
https://pubmed.ncbi.nlm.nih.gov/9476255
https://pubmed.ncbi.nlm.nih.gov/9476255
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 693(2)
A reversed-phase HPLC method was developed for the study of isradipine oxidation in vitro. The drug and its main metabolites were determined after extraction from culture media and from h3A4/OR cells having the cytochrome P450 isoenzyme involved in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5c722e9b54e28ed17476470218db9d7
https://pubmed.ncbi.nlm.nih.gov/9210440
https://pubmed.ncbi.nlm.nih.gov/9210440
Publikováno v:
Anticancer research. 17(3C)
This paper reports studies on the influence of multidrug resistance (MDR) on the mechanism of polyamine toxicity. The effects of putrescine (PUT), spermidine (SPD) and spermine (SPM) on morphonuclear parameters and cell cycle were studied by means of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2b6b96e48355d249b0f2ae493a4cb0b
https://pubmed.ncbi.nlm.nih.gov/9216664
https://pubmed.ncbi.nlm.nih.gov/9216664
Publikováno v:
Bulletin et memoires de l'Academie royale de medecine de Belgique. 150(5-6)
The differences between the metabolic schemes of polyamines can be the starting point to investigate the discovery of new antiparasitic or anticancer drugs which would be cell type specific. The studies, which were undertaken with the P388 cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73ae5f157f3def901e01f597e3408128
https://pubmed.ncbi.nlm.nih.gov/8696270
https://pubmed.ncbi.nlm.nih.gov/8696270
Publikováno v:
Journal de pharmacie de Belgique. 48(1)
Absorption and distribution of zinc in 6 dosage forms were determined in 10 subjects by performing a pharmacokinetic study of the serum zinc profile after oral administration of a dose corresponding to 45 mg elemental zinc. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f133c5b4bbc1e11d8aac5a125dd5e39
https://pubmed.ncbi.nlm.nih.gov/8483101
https://pubmed.ncbi.nlm.nih.gov/8483101
Autor:
J, Dubois, R, Arnould, F, Abikhalil, M, Hanocq, G, Atassi, G, Ghanem, A, Libert, F J, Lejeune
Publikováno v:
Anticancer research. 10(3)
The cytotoxicity of hexamethylmelamine (HMM) and its metabolites was investigated in three murine cell lines: one in vitro naturally sensitive to HMM (RC) and two in vivo naturally resistant (P388 and P388D1). The percentage of viable cells was deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12d4baf64cd1c9a2b6997742a495fc4f
https://pubmed.ncbi.nlm.nih.gov/2114821
https://pubmed.ncbi.nlm.nih.gov/2114821