Zobrazeno 1 - 10
of 62
pro vyhledávání: '"M, Haeck"'
Autor:
Satish Rojekar, Anusha R Pallapati, Judit Gimenez-Roig, Funda Korkmaz, Farhath Sultana, Damini Sant, Clement M Haeck, Anne Macdonald, Se-Min Kim, Clifford J Rosen, Orly Barak, Marcia Meseck, John Caminis, Daria Lizneva, Tony Yuen, Mone Zaidi
Publikováno v:
eLife, Vol 12 (2023)
Highly concentrated antibody formulations are oftentimes required for subcutaneous, self-administered biologics. Here, we report the development of a unique formulation for our first-in-class FSH-blocking humanized antibody, MS-Hu6, which we propose
Externí odkaz:
https://doaj.org/article/dbfcd21d71574f6ca1d659719f942a73
Autor:
Clément M. Haeck, Peter Boyd, Nastasia Dimant, Aurélie Barrail-Tran, Hélène Gouget, Roger Le Grand, Delphine Desjardins, R. Karl Malcolm
Publikováno v:
Haeck, C M, Boyd, P, Dimant, N, Barrail-Tran, A, Gouget, H, Le Grand, R, Desjardins, D & Malcolm, R K 2023, ' Preclinical development and pharmacokinetic assessment in macaques of a multipurpose long-acting injectable suspension containing medroxyprogesterone acetate for contraception and rilpivirine for HIV prevention ', Journal of Drug Delivery Science and Technology, vol. 85, 104590 . https://doi.org/10.1016/j.jddst.2023.104590
Depot injections comprising aqueous drug suspensions are widely marketed for long-acting administration of contraceptive progestins and antipsychotics. In recent years, there has been considerable interest in developing similar long-acting injectable
Publikováno v:
Acta gastro-enterologica Belgica. 83(1)
Quality of care is a very timely topic in medicine. We designed a questionnaire to measure perceived quality of care and to explore areas of improvement.In this prospective study a questionnaire was developed and administered to all patients with inf
Publikováno v:
International Journal of Pharmaceutics. 596:120234
Segesterone acetate (SA) is a promising and recently approved drug substance used as a contraceptive. SA has two major polymorphic forms, Form I and II. We have shown through indirect analysis that Form I is the more thermodynamically stable polymorp
Autor:
François Provôt, F. Moulonguet, A. Decaestecker, M. Haeck, M. Ulrich, C. Prouteau, Marc Hazzan, M. Van Triempont
Publikováno v:
Néphrologie & Thérapeutique. 15:356
Introduction Le purpura thrombotique thrombocytopenique acquis (PTTa) est une microangiopathie thrombotique (MAT) pouvant engager le pronostic vital, et dont la mortalite s’eleve a 15 %. Jusqu’en 2018, le traitement standard des patients a la pha
Publikováno v:
Néphrologie & Thérapeutique. 15:355
Introduction La microangiopathie thrombotique (MAT) est une pathologie rare au pronostic severe. Les progres therapeutiques, reposant sur les echanges plasmatiques et l’eculizumab, ont largement ameliore le pronostic. Ce traitement est peu efficace
Autor:
S. Malot, Paul Coppo, Eric Maury, Jean-François Augusto, Jean-Michel Halimi, M. Haeck, Christelle Barbet, François Provôt
Publikováno v:
Néphrologie & Thérapeutique. 15:277
Introduction Nous rapportons ici les premieres donnees d’utilisation en vie reelle du caplacizumab, nanocorps anti-Willebrand, indique dans la prise en charge du purpura thrombotique thrombocytopenique acquis (PTTa). Methodes Etude observationnelle
Publikováno v:
Journal of Psychiatric Research. 47:686-693
Background ECT is a well-established treatment for severe depression. The available data on psychosis are limited, but reliable. Its therapeutic potential relies on the induction of a generalized seizure. Besides other narcotics, methohexital and eto
Publikováno v:
Der Nervenarzt. 83:1468-1476
Die Psychoonkologie befasst sich mit der psychosozialen Betreuung von Patienten mit Krebserkrankungen. Seit wenigen Jahrzehnten werden die Wechselwirkungen zwischen den biologischen, psychischen und sozialen Faktoren vor, wahrend und nach einer Krebs
Autor:
I M Haeck, Marjolein S. de Bruin-Weller, C. A. F. M. Bruijnzeel-Koomen, Ton J. Rouwen, Linda Timmer-de Mik
Publikováno v:
Journal of the American Academy of Dermatology. 64:275-281
Introduction There is concern about the development of glaucoma and cataracts associated with topical corticosteroid use in patients with atopic dermatitis (AD). Objective We evaluated glaucoma and cataract development in patients with AD to determin