Zobrazeno 1 - 10
of 1 143
pro vyhledávání: '"M, Grayson"'
Autor:
Jason M. Grayson, Samantha M. Short, C. Jiah Lee, Nuri Park, Caitlyn Marsac, Alessandro Sette, Cecillia S. Lindestam Arlehamn, Xiaoyan I. Leng, Samuel N. Lockhart, Suzanne Craft
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Studies over the last 100 years have suggested a link between inflammation, infectious disease, and Alzheimer’s Disease (AD). Understanding how the immune system changes during the development of AD may facilitate new treatments. Here, we
Externí odkaz:
https://doaj.org/article/7324af31cb764696a74e89527ea98bdb
Autor:
I. Whitehead, G. W. Irwin, F. Bannon, C. E. Coles, E. Copson, R. I. Cutress, R. V. Dave, M. D. Gardiner, M. Grayson, C. Holcombe, S. Irshad, C. O’Brien, R. L. O’Connell, C. Palmieri, A. M. Shaaban, N. Sharma, J. K. Singh, S. Potter, S. A. McIntosh, on behalf of the NeST Study Research Collaborative
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Neoadjuvant systemic therapy (NST) is increasingly used in the treatment of breast cancer, yet it is clear that there is significant geographical variation in its use in the UK. This study aimed to examine stated practice across U
Externí odkaz:
https://doaj.org/article/3196506ac10e4a249fd5b755392b4528
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 1, Pp 86-90 (2020)
In 2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid, C8H14O4, the carboxyl group occupies an equatorial position on the 1,3-dioxane ring. In the crystal, O—H...O hydrogen bonds form chains of molecules, which are linked into a three-dimensional networ
Externí odkaz:
https://doaj.org/article/32f446df29c548f8ab08ee0c3d3efb8b
Autor:
Kelly L. Weaver, Catherine B. Blackwood, Alexander M. Horspool, Gage M. Pyles, Emel Sen-Kilic, Emily M. Grayson, Annalisa B. Huckaby, William T. Witt, Megan A. DeJong, M. Allison Wolf, F. Heath Damron, Mariette Barbier
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Over two decades ago acellular pertussis vaccines (aP) replaced whole cell pertussis vaccines (wP) in several countries. Since then, a resurgence in pertussis has been observed, which is hypothesized to be linked, in part, to waning immunity. To bett
Externí odkaz:
https://doaj.org/article/b03e1b6f45e14762b9f792aee88a0445
Autor:
J. Peng, I. Witting, N. Geisendorfer, M. Wang, M. Chang, A. Jakus, C. Kenel, X. Yan, R. Shah, G. J. Snyder, M. Grayson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Flexible thermoelectric composite threads are reported for wearable thermal energy harvesting platforms where rigid materials lack compatibility. Thermoelectric thread modules are demonstrated, and pressure-dependence shows thread compression to be e
Externí odkaz:
https://doaj.org/article/ff93eae3bec0439e9dcc710367388bba
Autor:
Wayne O. Hemphill, Sean R. Simpson, Mingyong Liu, Freddie R. Salsbury, Thomas Hollis, Jason M. Grayson, Fred W. Perrino
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Mutations in the TREX1 3’ → 5’ exonuclease are associated with a spectrum of autoimmune disease phenotypes in humans and mice. Failure to degrade DNA activates the cGAS-STING DNA-sensing pathway signaling a type-I interferon (IFN) response that
Externí odkaz:
https://doaj.org/article/6b112cac40a84ca48d20a8c220831359
Autor:
Jason M Grayson, Mildred D Perez, Rebecca Blevins, Benjamin N Coe, Michael R Detty, Zachariah A McIver
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234778 (2020)
Acute graft-versus-host-disease (GVHD), limits the use of hematopoietic cell transplant (HCT) to treat a variety of malignancies. Any new therapeutic approach must satisfy three requirements: 1) Prevent GVHD, 2) Maintain anti-pathogen immunity, and 3
Externí odkaz:
https://doaj.org/article/da710e4d070245cb8aa84ba01ac71515
Autor:
Stephen L. Rego, Scott Harvey, Sean R. Simpson, Wayne O. Hemphill, Zachariah A. McIver, Jason M. Grayson, Fred W. Perrino
Publikováno v:
Autoimmunity, Vol 51, Iss 7, Pp 333-344 (2018)
Anaemia is commonly observed in chronic inflammatory conditions, including systemic lupus erythematosus (SLE), where ∼50% of patients display clinical signs of anaemia. Mutation at the aspartate residue 18 of the three prime repair exonuclease 1 (T
Externí odkaz:
https://doaj.org/article/06dec58f951b405fb83abbad7386c8f4
Publikováno v:
ACS Polymers Au. 3:70-81