Zobrazeno 1 - 10
of 2 490
pro vyhledávání: '"M, Gorski"'
Autor:
Marie Morimoto, Vikas Bhambhani, Nour Gazzaz, Mariska Davids, Paalini Sathiyaseelan, Ellen F. Macnamara, Jennifer Lange, Anna Lehman, Patricia M. Zerfas, Jennifer L. Murphy, Maria T. Acosta, Camille Wang, Emily Alderman, Undiagnosed Diseases Network, Sara Reichert, Audrey Thurm, David R. Adams, Wendy J. Introne, Sharon M. Gorski, Cornelius F. Boerkoel, William A. Gahl, Cynthia J. Tifft, May Christine V. Malicdan
Publikováno v:
npj Genomic Medicine, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Autophagy regulates the degradation of damaged organelles and protein aggregates, and is critical for neuronal development, homeostasis, and maintenance, yet few neurodevelopmental disorders have been associated with pathogenic variants in g
Externí odkaz:
https://doaj.org/article/26c827d9dfcc46b4ace723c7df39bf58
Autor:
J. S. Gallagher, R. Kotulla, L. Laufman, E. Geist, S. Aalto, N. Falstad, S. König, J. Krause, G. C. Privon, C. Wethers, A. Evans, M. Gorski
Publikováno v:
The Astrophysical Journal Supplement Series, Vol 274, Iss 1, p 3 (2024)
Zw 049.057 is a moderate-mass, dusty, early-type galaxy that hosts a powerful compact obscured nucleus (CON, L _FIR,CON ≥ 10 ^11 L _⊙ ). The resolution of the Hubble Space Telescope enabled measurements of the stellar light distribution and chara
Externí odkaz:
https://doaj.org/article/9c11e293e6964e8685cd25f6fcaa59d3
Autor:
Samuel Knoedler, Dany Y. Matar, Leonard Knoedler, Doha Obed, Valentin Haug, Sabina M. Gorski, Bong-Sung Kim, Martin Kauke-Navarro, Ulrich Kneser, Adriana C. Panayi, Dennis P. Orgill, Gabriel Hundeshagen
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
IntroductionBurn injuries are associated with significant morbidity, often necessitating surgical management. Older patients are more prone to burns and more vulnerable to complications following major burns. While the relationship between senescence
Externí odkaz:
https://doaj.org/article/65447906e1b8428988e14bd5c30039b4
Autor:
Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is as
Externí odkaz:
https://doaj.org/article/a628231eefc547ca89a67c8ce3fcdf31
Autor:
Kevin C. Yang, Sharon M. Gorski
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101283- (2022)
Summary: RNA-sequencing and quantitative proteomic profiling simultaneously measure thousands of molecules and provide opportunities to decipher the transcriptomic and proteomic landscapes of cohort specimens for basic and health research. We present
Externí odkaz:
https://doaj.org/article/4fe8dce9ce3b43f1832816ec18e1139e
Publikováno v:
Frontiers in Environmental Science, Vol 9 (2021)
Topological data analysis (TDA) combines concepts from algebraic topology, machine learning, statistics, and data science which allow us to study data in terms of their latent shape properties. Despite the use of TDA in a broad range of applications,
Externí odkaz:
https://doaj.org/article/23d1921e4c484b01b29adc47cc05ab87
Autor:
D. Bosc, L. Vezenkov, S. Bortnik, J. An, J. Xu, C. Choutka, A. M. Hannigan, S. Kovacic, S. Loo, P. G. K. Clark, G. Chen, R. N. Guay-Ross, K. Yang, W. H. Dragowska, F. Zhang, N. E. Go, A. Leung, N. S. Honson, T. A. Pfeifer, M. Gleave, M. Bally, S. J. Jones, S. M. Gorski, R. N. Young
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-17 (2018)
Abstract The cysteine protease ATG4B is a key component of the autophagy machinery, acting to proteolytically prime and recycle its substrate MAP1LC3B. The roles of ATG4B in cancer and other diseases appear to be context dependent but are still not w
Externí odkaz:
https://doaj.org/article/9a9e47719cda4bf8a6d913a40f60c964
Autor:
Marcin M. Gorski, Anna Lecchi, Eti A. Femia, Silvia La Marca, Andrea Cairo, Emanuela Pappalardo, Luca A. Lotta, Andrea Artoni, Flora Peyvandi
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Primary platelet secretion defects constitute a heterogeneous group of functional defects characterized by reduced platelet granule secretion upon stimulation by different agonists. The clinical and laboratory heterogeneity of primary platelet secret
Externí odkaz:
https://doaj.org/article/b12e8da635254a0ea568052975181374
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Akademický článek
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