Zobrazeno 1 - 10
of 315
pro vyhledávání: '"M, Goergen"'
Autor:
Huy Quang Quach, Iana H. Haralambieva, Krista M. Goergen, Diane E. Grill, Jun Chen, Inna G. Ovsyannikova, Gregory A. Poland, Richard B. Kennedy
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Older age (≥ 65 years) is associated with impaired responses to influenza vaccination, leading to the preferential recommendation of MF59-adjuvanted (MF59Flu) or high-dose (HDFlu) influenza vaccines for this age group in the United States.
Externí odkaz:
https://doaj.org/article/ce51629654d646adb5d67b575001e389
Autor:
Abigail E. Asangba, Jun Chen, Krista M. Goergen, Melissa C. Larson, Ann L. Oberg, Jvan Casarin, Francesco Multinu, Scott H. Kaufmann, Andrea Mariani, Nicholas Chia, Marina R. S. Walther-Antonio
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Ovarian cancer (OC) is the second most common gynecological malignancy and the fifth leading cause of death due to cancer in women in the United States mainly due to the late-stage diagnosis of this cancer. It is, therefore, critical to iden
Externí odkaz:
https://doaj.org/article/c7bfec31158d4008840d29b28ac570cc
Autor:
Huy Quang Quach, Krista M. Goergen, Diane E. Grill, Iana H. Haralambieva, Inna G. Ovsyannikova, Gregory A. Poland, Richard B. Kennedy
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIn the vaccine era, individuals receive multiple vaccines in their lifetime. Host gene expression in response to antigenic stimulation is usually virus-specific; however, identifying shared pathways of host response across a wide spectrum o
Externí odkaz:
https://doaj.org/article/638ced6cb4414d19b5e35d96ecb3f2e6
Autor:
Ann L. Oberg, Ethan P. Heinzen, Xiaonan Hou, Mariam M. Al Hilli, Rachel M. Hurley, Andrea E. Wahner Hendrickson, Krista M. Goergen, Melissa C. Larson, Marc A. Becker, Jeanette E. Eckel-Passow, Matthew J. Maurer, Scott H. Kaufmann, Paul Haluska, S. John Weroha
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Repeated measures studies are frequently performed in patient-derived xenograft (PDX) models to evaluate drug activity or compare effectiveness of cancer treatment regimens. Linear mixed effects regression models were used to perform statist
Externí odkaz:
https://doaj.org/article/ff6b9ed53489469fac350642c746a06e
Autor:
Iana H. Haralambieva, Huy Quang Quach, Inna G. Ovsyannikova, Krista M. Goergen, Diane E. Grill, Gregory A. Poland, Richard B. Kennedy
Publikováno v:
Viruses, Vol 14, Iss 12, p 2763 (2022)
Older adults experience declining influenza vaccine-induced immunity and are at higher risk of influenza and its complications. For this reason, high dose (e.g., Fluzone) and adjuvanted (e.g., Fluad) vaccines are preferentially recommended for people
Externí odkaz:
https://doaj.org/article/48c0560093984df3a8f765aa03c492ae
Publikováno v:
Frontiers in Aging, Vol 2 (2021)
Introduction: Each year, a disproportionate number of the total seasonal influenza-related hospitalizations (90%) and deaths (70%) occur among adults who are >65 years old. Inflammasome activation has been shown to be important for protection against
Externí odkaz:
https://doaj.org/article/885c07610ddb4c38b9465b2b69e16f91
Autor:
Emily A. Voigt, Inna G. Ovsyannikova, Richard B. Kennedy, Diane E. Grill, Krista M. Goergen, Daniel J. Schaid, Gregory A. Poland
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Sex differences in immune responses to influenza vaccine may impact efficacy across populations.Methods: In a cohort of 138 older adults (50–74 years old), we measured influenza A/H1N1 antibody titers, B-cell ELISPOT response, PBMC tran
Externí odkaz:
https://doaj.org/article/652c6a6c62a84f62b960c39f93f5f2fc
Autor:
Ellen L. Goode, Keith L. Knutson, Lara E. Sucheston, Kunle Odunsi, Roberta B. Ness, Simon A. Gayther, Paul D.P. Pharoah, Georgia Chenevix-Trench, Mary Anne Rossing, Daniel W. Cramer, Celeste Leigh Pearce, Joellen M. Schildkraut, Usha Menon, Susanne K. Kjaer, Douglas A. Levine, Jacek Gronwald, Hoda Anton Culver, Alice S. Whittemore, Beth Y. Karlan, Diether Lambrechts, Nicolas Wentzensen, Jolanta Kupryjanczyk, Jenny Chang-Claude, Elisa V. Bandera, Estrid Hogdall, Florian Heitz, Stanley B. Kaye, Gottfried Konecny, Peter A. Fasching, Ian Campbell, Marc T. Goodman, Tanja Pejovic, Yukie T. Bean, Laura E. Hays, Galina Lurie, Diana Eccles, Alexander Hein, Matthias W. Beckmann, Arif B. Ekici, James Paul, Robert Brown, James M. Flanagan, Philipp Harter, Andreas du Bois, Ira Schwaab, Claus K. Hogdall, Sara H. Olson, Lene Lundvall, Irene Orlow, Lisa E. Paddock, Anja Rudolph, Petra Seibold, Agnieszka Dansonka-Mieszkowska, Iwona K. Rzepecka, Beata Spiewankiewicz, Louise A. Brinton, Hannah Yang, Montserrat Garcia-Closas, Evelyn Despierre, Sandrina Lambrechts, Ignace Vergote, Christine Walsh, Jenny Lester, Weiva Sieh, Valerie McGuire, Joseph H. Rothstein, Argyrios Ziogas, Jan Lubiński, Cezary Cybulski, Janusz Menkiszak, Allan Jensen, Howard Shen, Brenda Diergaarde, Susan J. Ramus, Aleksandra Gentry-Maharaj, Andrew Berchuck, Anna H. Wu, Malcolm C. Pike, David Van Den Berg, Kathryn L. Terry, Allison F. Vitonis, Starr M. Ramirez, Thomas A. Sellers, Catherine M. Phelan, Jennifer A. Doherty, Sharon E. Johnatty, Anna deFazio, Honglin Song, Jonathan Tyrer, Chen Wang, Kate Lawrenson, Lynn C. Hartmann, Claudia Preston, David N. Rider, Julie M. Cunningham, Brooke L. Fridley, Krista M. Goergen, Matthew J. Maurer, Matthew S. Block, Zachary C. Fogarty, Robert A. Vierkant, Ann L. Oberg, Kimberly R. Kalli, Kirsten B. Moysich, Bridget Charbonneau
PDF file - 157K, Supplemental Table 1. Regulatory T cell genes included in this study (N=25). Supplemental Table 2. Regulatory T cell SNPs included in this study. Supplemental Table 3. Participating invasive epithelial ovarian cancer studies. Supplem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7722e406438cc706f8ada9698d1e052e
https://doi.org/10.1158/2326-6066.22538465
https://doi.org/10.1158/2326-6066.22538465
Autor:
Ellen L. Goode, Keith L. Knutson, Lara E. Sucheston, Kunle Odunsi, Roberta B. Ness, Simon A. Gayther, Paul D.P. Pharoah, Georgia Chenevix-Trench, Mary Anne Rossing, Daniel W. Cramer, Celeste Leigh Pearce, Joellen M. Schildkraut, Usha Menon, Susanne K. Kjaer, Douglas A. Levine, Jacek Gronwald, Hoda Anton Culver, Alice S. Whittemore, Beth Y. Karlan, Diether Lambrechts, Nicolas Wentzensen, Jolanta Kupryjanczyk, Jenny Chang-Claude, Elisa V. Bandera, Estrid Hogdall, Florian Heitz, Stanley B. Kaye, Gottfried Konecny, Peter A. Fasching, Ian Campbell, Marc T. Goodman, Tanja Pejovic, Yukie T. Bean, Laura E. Hays, Galina Lurie, Diana Eccles, Alexander Hein, Matthias W. Beckmann, Arif B. Ekici, James Paul, Robert Brown, James M. Flanagan, Philipp Harter, Andreas du Bois, Ira Schwaab, Claus K. Hogdall, Sara H. Olson, Lene Lundvall, Irene Orlow, Lisa E. Paddock, Anja Rudolph, Petra Seibold, Agnieszka Dansonka-Mieszkowska, Iwona K. Rzepecka, Beata Spiewankiewicz, Louise A. Brinton, Hannah Yang, Montserrat Garcia-Closas, Evelyn Despierre, Sandrina Lambrechts, Ignace Vergote, Christine Walsh, Jenny Lester, Weiva Sieh, Valerie McGuire, Joseph H. Rothstein, Argyrios Ziogas, Jan Lubiński, Cezary Cybulski, Janusz Menkiszak, Allan Jensen, Howard Shen, Brenda Diergaarde, Susan J. Ramus, Aleksandra Gentry-Maharaj, Andrew Berchuck, Anna H. Wu, Malcolm C. Pike, David Van Den Berg, Kathryn L. Terry, Allison F. Vitonis, Starr M. Ramirez, Thomas A. Sellers, Catherine M. Phelan, Jennifer A. Doherty, Sharon E. Johnatty, Anna deFazio, Honglin Song, Jonathan Tyrer, Chen Wang, Kate Lawrenson, Lynn C. Hartmann, Claudia Preston, David N. Rider, Julie M. Cunningham, Brooke L. Fridley, Krista M. Goergen, Matthew J. Maurer, Matthew S. Block, Zachary C. Fogarty, Robert A. Vierkant, Ann L. Oberg, Kimberly R. Kalli, Kirsten B. Moysich, Bridget Charbonneau
The presence of regulatory T cells (Treg) in solid tumors is known to play a role in patient survival in ovarian cancer and other malignancies. We assessed inherited genetic variations via 749 tag single-nucleotide polymorphisms (SNP) in 25 Treg-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::760a314079de9d990758344e53bf99e8
https://doi.org/10.1158/2326-6066.c.6548789.v1
https://doi.org/10.1158/2326-6066.c.6548789.v1
Autor:
Matthew S. Block, Keith L. Knutson, Marshall D. Behrens, Courtney L. Erskine, Kimberly R. Kalli, Krista M. Goergen, Matthew J. Maurer, Aaron M. Carlson
Background: Epithelial ovarian cancer (EOC) is the fifth leading cause of cancer-related death in females and leading gynecologic cause of cancer-related death. Despite the identification of a number of serum biomarkers, methods to identify early-sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569b82f6120a2bc41a4bc8da6f45b3f3
https://doi.org/10.1158/1055-9965.c.6515745.v1
https://doi.org/10.1158/1055-9965.c.6515745.v1